Modulatory role of the mPFC orexin-2 receptors in the acquisition and expression in two paradigms of the natural- and drug-induced conditioned place preference in the rats [0.03%]
mPFC orexin-2受体在大鼠自然和药物诱导的两类条件位置偏爱建立与表现中的调制作用
Shole Jamali,Mahboobeh Mirmohammadi,Ronak Azizbeigi et al.
Shole Jamali et al.
The neuropeptide orexin/hypocretin regulates adaptive behaviors needed for survival, including food intake, sleep-wake regulation, mating, and maternal behavior. However, the orexinergic system plays a critical role in addictive behavior an...
Gray Matter Volume Alterations in Generalized Anxiety Disorder and Major Depressive Disorder [0.03%]
焦虑症和抑郁症的灰质体积变化
Jiakuai Yu,Shunshun Cui,Qinghong Hu et al.
Jiakuai Yu et al.
Background: Generalized anxiety disorder (GAD) and major depressive disorder (MDD) are highly comorbid and clinically overlapping, but their shared and differential structural brain alterations remain unclear. This study ...
Corrigendum to "Behavioral characterization of bulbar sensorimotor function in a rat model of Alexander disease" [Behav. Brain Res. 514 (2026) 116359] [0.03%]
“帕金森病大鼠模型中球状区传感器灵功能的行为特征”一文的勘误(2026年发表于Behavioral Brain Research杂志第514卷116359页)
Jared S Cullen,John A Russell,Cynthia A Kelm-Nelson et al.
Jared S Cullen et al.
Published Erratum
Behavioural brain research. 2026 Aug 8:116412. DOI:10.1016/j.bbr.2026.116412 2026
Akkermansia muciniphila gavage alleviates depression-like behaviors in female A53T α-synuclein transgenic mice [0.03%]
口服定植粘液乳杆菌改善A53Tα-突触核蛋白转基因小鼠的抑郁样行为
Shuyu Li,Xingkun Chu,Rui Deng et al.
Shuyu Li et al.
Parkinson's disease (PD) is characterized not only by progressive motor deficits but also by non-motor symptoms, such as depression, which often emerge during the prodromal stage and significantly impair quality of life. While Akkermansia m...
Differential association of high- and low-frequency rat vocalizations with breathing and locomotion during social interactions [0.03%]
高频和低频大鼠叫声与社交互动期间呼吸和运动的关联性不同
Yizhaq Goussha,Noemi Foà,Rishika Tiwari et al.
Yizhaq Goussha et al.
Rodents, including rats, utilize vocalizations as a primary mode of social communication. While high-frequency ultrasonic vocalizations (USVs) have been extensively explored in laboratory rats, low-frequency (
Creatine preserves mitochondrial integrity and ameliorates early epileptiform activity and cognitive impairment via regulation of Na⁺,K⁺-ATPase in adolescent rats with severe traumatic brain injury [0.03%]
肌酸通过调节Na⁺,K⁺-ATP酶来维持线粒体的完整性，并改善青少年重型创伤性脑损伤的大鼠早期癫痫样放电和认知障碍
Luiz Fernando Freire Royes,Guilherme Lago Busanello,Douglas Buchmann Godinho et al.
Luiz Fernando Freire Royes et al.
In this study, we demonstrate for the first time that post-injury creatine supplementation (300 mg/kg, p.o.) administered for two weeks attenuates blood-brain barrier disruption, cortical lesion volume (by ∼60%), spatial memory deficits (r...
Developmental differences in broad versus selective approach responses to ultrasonic vocalizations in rats: involvement of amygdala and nucleus accumbens activity [0.03%]
大鼠超声波发声的广谱式反应和选择式反应的发育差异：杏仁核和伏隔核活动的参与作用
Yumi Saito,Kazuo Okanoya
Yumi Saito
Rats emit ultrasonic vocalizations (USVs) that function as affective and social acoustic cues. In adults, 50-kHz USVs are associated with appetitive states, whereas 22-kHz USVs are associated with aversive or defensive contexts. However, de...
Huiling Cai,Qinglu Suo,Qiuyin Li et al.
Huiling Cai et al.
Personality disorders (PDs) are increasingly recognized and highly prevalent, yet remarkably poorly understood, diagnosed and treated mental conditions. Common PDs include antisocial, avoidant, borderline, dependent, histrionic, narcissisti...
Falls induced by optogenetic inhibition of basal forebrain cholinergic neurons after dorsomedial striatal dopamine depletion in a dual disruption model of falling vulnerability in Parkinson's disease [0.03%]
帕金森病双重损伤跌倒模型中纹状体多巴胺耗竭后基底前脑胆碱能神经元光遗传抑制诱发的跌倒
Aaron Kucinski
Aaron Kucinski
Falls are a common and debilitating feature of Parkinson's Disease (PD) patients. Prefrontal acetylcholine (ACh) deficits, as well as nigrostriatal dopamine deficits, are implicated in vulnerability to falls. PD patients with loss of cortic...
Disrupted Multi-frequency Topological Properties of Brain Functional Networks in Attention Networks after Repetitive Subconcussion [0.03%]
重复亚脑震荡后注意网络脑功能网络的多频拓扑性质改变
Chengfang Wang,Jian Song,Shuochen Wang et al.
Chengfang Wang et al.
Attention impairment constitutes a primary cognitive deficit following subconcussive head impacts. However, the underlying neural mechanisms remain unclear. This study investigated neural alterations in attention networks associated with re...