The Drosophila aryl hydrocarbon receptor ortholog, spineless, modulates survival and reproduction [0.03%]
拟南芥芳香烃受体直向同源基因spineless调控生存和繁殖
Shelton G Swint,Shengshuai Shan,Jessica M Hoffman
Shelton G Swint
The aryl hydrocarbon receptor (AhR) is a highly conserved, ligand-activated transcription factor in mammals involved in multiple physiological processes, including development, xenobiotic detoxification, and potentially aging, and some of t...
The DExD-box RNA helicase Dbp7 unwinds short double-stranded RNAs [0.03%]
DExD-box RNA解旋酶Dbp7能够解开短双链RNA
Julia Contreras,Régine Capeyrou,Yves Henry et al.
Julia Contreras et al.
DExD-box proteins are ATP-dependent enzymes that unwind double-stranded RNAs in a non-processive manner, often initiating strand separation from 5'- or 3'-single-stranded overhangs. Dbp7, a member of this family, is required for yeast ribos...
The hills are alive with the sound of venom: Clinical implications of intraspecific variations in Factor Va mediated activations of Factor VII and Factor X in Swiss populations of Vipera aspis (Asp Viper) [0.03%]
毒蛇出没，音符缭绕：欧洲鳞头 viper（Vipera aspis）种群中瑞士人群血管反应素介导的活化 VII 和 X 因子的临床意义
Katrina Kempson,Patrick S Champagne,Lorenzo Seneci et al.
Katrina Kempson et al.
This study investigated the individual variation in the procoagulant toxicity of Vipera aspis venoms collected from multiple Swiss localities, in addition to the neutralisation capacity of three currently available antivenoms. Functional co...
A non-canonical, moonlighting Acinetobacter baumannii glyceraldehyde-3-phosphate dehydrogenase (GAPDH/GapA) promotes iron acquisition from heme, transferrin and lactoferrin [0.03%]
一种非典型的人源鲍曼不动杆菌甘油醛-3-磷酸脱氢酶（GAPDH/GapA）促进血红素、转铁蛋白和乳铁蛋白的铁获取作用
Anjali Kumari,Zahid Gani,Nimma Ramesh et al.
Anjali Kumari et al.
Acinetobacter baumannii (A. baumannii) has emerged a priority pathogen due the rapid spread of multi-drug resistant strains. Despite this, a number of metabolic pathways of this pathogen remain uncharacterized and are inferred from studies ...
Pre-Amplified dsDNA-Tag Lateral Flow Assay for Highly Sensitive Point-of-Care Detection of Influenza A H1N1 [0.03%]
用于高灵敏度护理点检测甲型H1N1流感的预放大的dsDNA-标签侧向流动测定法
Lingling Wang,Hongyu Zhou,Shengjun Bu et al.
Lingling Wang et al.
The current immediate detection of influenza A (H1N1) virus faces the dual challenges of insufficient sensitivity and the risk of amplification contamination. Here, we developed a novel lateral flow nucleic acid biosensor using pre-amplifie...
Purification and functional characterization of two basic proteases of South American Bromelia antiacantha fruit [0.03%]
南美洲菠萝蜜果实两种碱性蛋白酶的分离纯化和功能表征
Diego Vallés,Carolina Villadóniga,Ana M B Cantera
Diego Vallés
Proteolytic enzymes from the bromeliad family are valuable biocatalysts with a broad range of biotechnological applications, thanks to their stability and broad substrate specificity. In this study, two novel cysteine proteases, AntB and An...
Characterization of the sweetness of natural plant-derived sweeteners mogroside IV and V and their interactions with human sweet taste receptor [0.03%]
罗汉果苷IV和V的甜味特征及其与人甜味受体的相互作用
Binbin Yao,Cunli Dou,Yuyu Zhang et al.
Binbin Yao et al.
Mogrosides are an important type of natural plant-derived sweeteners, which are used in foods and medicines. However, their sweetness and structure-activity relationship, especially those for the representative members mogrosides IV and V, ...
MicroRNA-mediated regulation of hypoxic kidney adaptation in naked mole-rats (Heterocephalus glaber) [0.03%]
裸鼹鼠(Heterocephalus glaber)缺氧条件下microRNA介导的肾脏适应性调控
Yasser Attaie,Sarah A Breedon,Saif Rehman et al.
Yasser Attaie et al.
MicroRNAs play crucial roles in post-transcriptional regulation during environmental stress, yet their contribution to hypoxia adaptation in naturally hypoxia-tolerant species remains poorly understood. Here, we characterized the miRNA expr...
Comparison of proteomes and biofunctional properties of male and female common adder (Vipera berus) venoms [0.03%]
雄性与雌性蛇毒蛋白组及生物功能的比较研究
Lennart Schulte,Miguel Engelhardt,Johanna Eichberg et al.
Lennart Schulte et al.
Snake venom is an ecologically critical functional trait, primarily applied for foraging and accordingly shaped by selective pressures. Recent insights underpinned the high variability of snake venoms down to the intraspecific level, with r...
Dioclea violacea Lectin Preserves Brain Mitochondrial Function and Prevents Oxidative Damage after Ischemia/Reperfusion [0.03%]
Dioclea violacea lectin保护缺血再灌注后线粒体功能并预防氧化损伤的作用
Pedro Lourenzo Oliveira Cunha,Maria Stella Batista de Freitas Neta,Ludmila Araújo de Lima et al.
Pedro Lourenzo Oliveira Cunha et al.
Ischemic brain damage is characterized by mitochondrial dysfunction and oxidative stress. Mitochondrial reactive oxygen species induce cellular damage during reperfusion. Dysregulated mitochondrial calcium influx triggers the opening of the...