Regulation of lipid metabolism by epigenetic mechanisms. Application to microalgae [0.03%]
表观遗传调控油脂代谢的机制及微藻应用研究进展
Elisa Rek,Anthony Kwasiborski,Martine Côme et al.
Elisa Rek et al.
Microalgae are emerging as valuable model systems for studying epigenetic regulation in unicellular eukaryotes and as promising platforms for biotechnological lipid production. In these organisms, DNA and RNA methylation, histone modificati...
Xin Yuan,Jingjing Wang,Baoyu Sun et al.
Xin Yuan et al.
Acinetobacter baumannii is a major nosocomial pathogen, and its increasing multidrug-resistant and pandrug-resistant profiles pose a serious challenge to anti-infective therapy. In recent years, heteroresistance to multiple antibiotics in A...
Altered plasma omega-3 fatty acids and nutritional status are associated with SARC-F based sarcopenia risk assessment in cardiovascular disease [0.03%]
心血管疾病患者血浆ω-3脂肪酸和营养状况与SARC-F介导的肌少症风险评估相关性研究
Khadijetou Bowbe,Sounira Mehri,Hayet M&#x;hamdi et al.
Khadijetou Bowbe et al.
This study aimed to assess nutritional status, analyze fatty acid profile, evaluate oxidative stress markers, and examine their associations with sarcopenia in patients with cardiovascular disease. Ninety-five adults over 60 years old with ...
Selenium Nanoparticle Synthesis in Stenotrophomonas maltophilia: Mutagenesis and Molecular Mechanisms [0.03%]
不动杆菌门无乳链球菌硒纳米粒子的合成：诱变及分子机制研究
Fan Wan,Yujie Wang,Xinyao Wang et al.
Fan Wan et al.
Biosynthetic selenium nanoparticles (SeNPs) exhibit superior bioavailability and detoxification potential compared to inorganic selenium forms. In this study, the strain Stenotrophomonas maltophilia SE5, isolated from the feces of piglets (...
Differential cardiac microRNA expression in anoxic Trachemys scripta elegans turtles [0.03%]
密闭状态下红耳滑龟心脏微小核糖核酸的差异表达研究
Tighe Bloskie,Olawale O Taiwo,William G Willmore et al.
Tighe Bloskie et al.
Red-eared slider turtles (Trachemys scripta elegans) possess exceptional tolerance to prolonged periods of anoxia, surviving seasonally in oxygen-deprived environments without apparent cardiac damage. This resilience is supported by deep me...
Renal failure-driven luminal ammonia production impairs gut barrier function in CKD [0.03%]
慢性肾脏病患者肠道屏障功能损害新的机制：肾衰驱动的肠腔内氨生成
Patricia Pereira Almeida,Elsa Hoibian,Milena Barcza Stockler-Pinto et al.
Patricia Pereira Almeida et al.
Chronic kidney disease (CKD) is often associated with increased intestinal permeability, commonly referred to as "leaky gut." This study aimed to investigate how uremic conditions affect gut barrier integrity using in vitro, ex vivo, and in...
Conditional Knockout of Indoleamine 2, 3-Dioxygenase-1 in Osteoprogenitor Cells in Mice Results in Sex-dependent Differences in Bone Mass [0.03%]
条件性敲除小鼠成骨前体细胞中的吲哚胺2，3-双加氧酶1导致性别依赖性的骨量差异
Baolin Kang,Wendy B Bollag,Diego Buxeda et al.
Baolin Kang et al.
Tryptophan is an essential amino acid metabolized in the body primarily through enzymatic degradation involving indoleamine and tryptophan 2,3-dioxygenase (IDO and TDO), generating kynurenine as the initial step, and ultimately leads to mul...
Sedentariness disrupts, while exercise restores, thermogenic and metabolic plasticity in inguinal adipose tissue of mice [0.03%]
久坐行为会破坏但运动会恢复小鼠腹股沟脂肪组织的生热和代谢可塑性
Bijayashree Sahu,Unmod Senapati,Punyadhara Pani et al.
Bijayashree Sahu et al.
Inguinal WAT (IngWAT) quickly adapts its metabolism to body energy status variations, including uncoupling protein 1 (UCP1) expression. However, its long-term metabolic response to long-term sedentary and exercise training has not been full...
Chrononutrition as a modulator of retinal metabolic resilience: A translational framework linking circadian biology to ocular disease [0.03%]
chrono营养学作为视网膜代谢韧性的调节因子：一个连接昼夜生物学和眼部疾病的转化框架
D Alemán-González-Duhart,L Mandujano-Ferrer
D Alemán-González-Duhart
Chrononutrition-the alignment of feeding-fasting cycles with endogenous circadian rhythms-has emerged as a key determinant of systemic metabolic homeostasis. However, its relevance in ocular biology and retinal disease remains insufficientl...
Heterologous Expression, Purification, and Biophysical Characterisation of the Cobalt-Dependent Nitrile Hydratase from Rhodococcus rhodochrous ATCC BAA-870 [0.03%]
来自Rhodococcus rhodochrous ATCC BAA-870的依赖于钴的氰基水合酶的异源表达、纯化及生物物理性质表征
Ateret Ben-David,Olalekan Onisuru,Blessing Oyiogu et al.
Ateret Ben-David et al.
Nitrile hydratases (NHases) are cobalt-dependent metalloenzymes that catalyse the hydration of nitriles to amides and are widely employed as industrial biocatalysts in the sustainable production of pharmaceuticals, polymers, and fine chemic...