Mitochondria-controlled neuropeptide release induces oxidative stress resistance [0.03%]
线粒体控制的神经肽释放诱导氧化应激抵抗
Florian Ullrich
Florian Ullrich
Tristan I Croll,Kay Diederichs,Florens Fischer et al.
Tristan I Croll et al.
Structural biology plays a crucial role in the fight against COVID-19, permitting us to ‘see’ and understand SARS-CoV-2. However, the macromolecular structures of SARS-CoV-2 proteins that were solved with great speed and urgency can conta...
A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation [0.03%]
H2A.Z.1在调节RNA聚合酶II转录起始和延伸动力学中的双重作用
Constantine Mylonas,Choongman Lee,Alexander L Auld et al.
Constantine Mylonas et al.
RNA polymerase II (RNAPII) pausing immediately downstream of the transcription start site is a critical rate-limiting step for the expression of most metazoan genes. During pause release, RNAPII encounters a highly conserved +1 H2A.Z nucleo...
Helen M Berman
Helen M Berman
Art as a tool for science [0.03%]
艺术作为科学的工具
David S Goodsell
David S Goodsell
Publisher Correction: A systems view of spliceosomal assembly and branchpoints with iCLIP [0.03%]
出版更正：使用 iclip 从系统角度审视剪接体的组装和分支点
Michael Briese,Nejc Haberman,Christopher R Sibley et al.
Michael Briese et al.
Published Erratum
Nature structural & molecular biology. 2021 May;28(5):455. DOI:10.1038/s41594-021-00595-5 2021
How to build a proteasome [0.03%]
如何构建蛋白酶体
Edward P Morris,Paula C A da Fonseca
Edward P Morris
Marco Igor Valencia-Sánchez,Stephen Abini-Agbomson,Miao Wang et al.
Marco Igor Valencia-Sánchez et al.
Certain large DNA viruses, including those in the Marseilleviridae family, encode histones. Here we show that fused histone pairs Hβ-Hα and Hδ-Hγ from Marseillevirus are structurally analogous to the eukaryotic histone pairs H2B-H2A and...
Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins [0.03%]
靶向尼帕病毒和亨德拉病毒融合糖蛋白的广谱中和抗体鸡尾酒疗法
Ha V Dang,Robert W Cross,Viktoriya Borisevich et al.
Ha V Dang et al.
Hendra virus (HeV) and Nipah virus (NiV) are henipaviruses (HNVs) causing respiratory illness and severe encephalitis in humans, with fatality rates of 50-100%. There are no licensed therapeutics or vaccines to protect humans. HeV and NiV u...