A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation
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RNA polymerase II (RNAPII) pausing immediately downstream of the transcription start site is a critical rate-limiting step for the expression of most metazoan genes. During pause release, RNAPII encounters a highly conserved +1 H2A.Z nucleosome, yet how this h... ...
