Triflic Anhydride-Mediated Cycloacylation of [60]Fullerene with 1-Naphthoic Acids: Synthesis and Derivatization of [60]Fullerene-Fused Dihydrophenalenones [0.03%]
Xinmin Huang,Zhiwei Xu,Wen-Jie Qiu et al.
Xinmin Huang et al.
An efficient triflic anhydride-mediated synthesis of [60]fullerene (C60)-fused dihydrophenalenones from C60 and 1-naphthoic acids has been developed, representing the first one-step construction of C60-fused polyaromatic ketones under metal...
Visible-Light-Induced Bi2O3 Catalysis toward 2-fold gem-Difluoroalkylation of Quinoxalinones [0.03%]
Karunamayee Mondal,Karthikeyan Jayabalan,Mahima Pilania et al.
Karunamayee Mondal et al.
A 2-fold gem-difluoroalkylation of quinoxalinones with exclusive C3 and C5 position selectivity is reported using inexpensive semiconductor Bi2O3 as a photocatalyst under visible-light irradiation. The protocol is distinguished by its uncon...
Tetrasargltones A and B, Fully Helically Polymerized Lindenane Sesquiterpenoid Tetramers from Sarcandra glabra [0.03%]
Danyang Zhang,Yu Zhao,Zhiqi Xiao et al.
Danyang Zhang et al.
Tetrasargltones A and B (1 and 2, respectively), representing the first examples of lindenane sesquiterpenoid (LS) tetramers, were isolated from Sarcandra glabra. Their structures were fully elucidated via HR-MS and NMR, with their authenti...
A Catalyst-Free, Tyrosine-Selective Bioconjugation Strategy via Triazine-Pyridine Chemistry for Antibodies [0.03%]
Shanyue Zheng,Chaoming Wang,Yifan Wang et al.
Shanyue Zheng et al.
A catalyst-free, tyrosine-selective bioconjugation strategy was successfully developed by utilizing triazine-pyridine chemistry. This approach employs 1,3,5-triazine-pyridinium probes to achieve efficient and selective modification of tyros...
Exploring γ-Nitroketones as 1,4-Dicarbonyl Precursors for Annulation to Pyridazines through Interrupted Nef Reaction [0.03%]
通过中断的Nef反应探索γ-硝基酮作为并环吡啶𬭩合成中1,4-二羰基前体的应用研究
Hitesh Kumar Labana,Shubham Tiwari,Ankush Gupta et al.
Hitesh Kumar Labana et al.
A practical approach toward pyridazine synthesis has been realized by exploring an interrupted Nef reaction strategy using a combination of sulfur and hydrazine. The access to pyridazine was accomplished through a challenging 1,4-dicarbonyl...
Liu Yang,Jie Li,Wanxiang Zhao
Liu Yang
Transition-metal-catalyzed asymmetric hydroboration of alkenes has emerged as a powerful tool for constructing chiral boronates, yet asymmetric hydroboration of functionalized alkenes remains underdeveloped. Herein, we report a cobalt-catal...
Difunctionalization of Aldehydes via Electrophilic Acylation: Access to α-Acyloxyphosphonium Salts and Subsequent Diversely Substituted Enol Esters [0.03%]
醛的亲电酰基化反应：α-酯氧磷盐及多取代烯醇酯的合成
Yuting Zhang,Lu Sun,Wenjuan Mao et al.
Yuting Zhang et al.
The synthesis of sterically hindered α-functionalized phosphonium salts is of significant interest yet remains challenging. This work presents a difunctionalization of aldehydes with electrophilic acylphosphonium salts to access α-acyloxy...
N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Inherently Chiral Pillar[5]arenes [0.03%]
手性氮杂环卡宾催化内固有手性的柱芳烃的不对称合成
Yinsheng Qi,Xuange Cui,Xiyu Li et al.
Yinsheng Qi et al.
Catalytic asymmetric synthesis of inherently chiral pillar[5]arene derivatives is promising in materials science, chemical biology, and host-guest chemistry due to their unique pillar structure. In this work, we developed an N-heterocyclic ...
Electrochemical Chemo- and Regioselective Reduction of Vicinal Diketones to α-Hydroxy Ketones [0.03%]
邻二酮的电化学高立体/区域选择性还原生成α-羟基酮
Yinfeng Zhang,Shilong Cao,Duanyang Kong
Yinfeng Zhang
α-Hydroxy ketones are valuable motifs in bioactive molecules and versatile synthetic intermediates, yet their selective preparation from vicinal diketones remains challenging due to issues of chemoselectivity, regioselectivity, and sustain...
Photoinduced TBADT-Catalyzed Alkylation of Alkyl (E)-3-(2-Methacrylamidoaryl)acrylates to Access 3,4-Dihydroquinolin-2-(1 H)-ones [0.03%]
光诱导TBADT催化下(E)-3-(2-丙烯酰胺基芳基)丙烯酸烷基酯的烷基化反应以合成3,4-二氢异喹啉-2(1H)-酮类化合物
Sadu Thirumala Rao,Gedu Satyanarayana
Sadu Thirumala Rao
Herein, we present a sustainable photochemical approach for the synthesis of 3,4-dihydroquinolin-2-(1H)-ones via TBADT (hydrogen-atom transfer) catalyst-mediated radical cascade cyclization of alkyl (E)-3-(2-methacrylamidoaryl)acrylates wit...