Exploring γ-Nitroketones as 1,4-Dicarbonyl Precursors for Annulation to Pyridazines through Interrupted Nef Reaction
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A practical approach toward pyridazine synthesis has been realized by exploring an interrupted Nef reaction strategy using a combination of sulfur and hydrazine. The access to pyridazine was accomplished through a challenging 1,4-dicarbonyl intermediate throug... ...