Synthesis of Benzarsoles by Arsenic Cation-Mediated Formal [3 + 2]-Cycloaddition with Alkynes [0.03%]
由砷介导的炔烃[3+2]环加成反应合成苯并苊烯化合物
Hiroki Iwamoto,Kazutoshi Nishimura,Kosuke Yasui et al.
Hiroki Iwamoto et al.
A Tf2O-mediated formal [3 + 2]-cycloaddition of phenylarsine oxide and internal alkynes has been developed. An initially formed arsenic dication undergoes disproportionation to form key arsenic cation species, which are then coupled with al...
Stereospecific Coupling of Alcohols and Carbanion Nucleophiles through a Circular P(V) Activation Manifold [0.03%]
通过圆形P(V)活化体系实现醇和碳负离子亲核试剂的立体专一性偶联反应
Isabel L Wood,Stephen P Argent,Ross M Denton
Isabel L Wood
We report a method for the stereospecific construction of sp3-sp3 carbon-carbon bonds using alcohols and carbanion nucleophiles. The process is based on a circular phosphorus(V) manifold which starts and ends with triphenylphosphine oxide. ...
N-Annulated Indenofluorene: An Isomeric Motif for N-Annulated Perylene [0.03%]
N-嵌吲哚荧烯：N-稠合perylenes同分异构体基元
Hemonta Kumar Saha,Tarun,Dibyendu Mallick et al.
Hemonta Kumar Saha et al.
N-Annulated indenofluorene (NIF), a structural isomer of the well-known N-annulated perylene (NP), has been synthesized. While the band gap of NP is larger than that of perylene, the band gap of NIF (1.40 eV) is smaller than that of parent ...
Radical-Polar Crossover Enabled Photoredox 1,2-Carbosulfinylation of Alkenes with N-Sulfinyltritylamine [0.03%]
光红氧化还原环化反应制备α-亚磺基酮类化合物
Wei Hu,Li Zhao,Yahan Zhang et al.
Wei Hu et al.
The alkylation of N-sulfinylamines has emerged as a straightforward and promising platform for the construction of sulfinamides. Nevertheless, extant strategies─whether through two-electron nucleophilic addition or single-electron radical ...
Sequential Gold and Organocatalyzed Bicyclization for Asymmetric Construction of Contiguous Tetrasubstituted Carbon Stereocenters [0.03%]
序贯金和有机催化双环化反应构建连续四取代碳立体中心的不对称合成方法研究
Jie Wang,Yi Gao,Xin-Zhe Niu et al.
Jie Wang et al.
Employing a sequential gold and organocatalytic system, we have achieved a one-pot double annulation of versatile 1,3-dicarbonyl compounds bearing a 3-butynoic acid moiety. This process proceeds through a gold-catalyzed 5-endo-dig cyclizati...
Stereochemical Reassignment by Total Synthesis of an Ocular Pyridinium Bisretinoid of Retinal Pigment Epithelium Lipofuscin: iiso-A2E Is i-A2E [0.03%]
视网膜色素上皮脂褐素的眼内吡啶𬭩双维甲醇 Stereochemical Reassignment by Total Synthesis of an Ocular Pyridinium Bisretinoid of Retinal Pigment Epithelium Lipofuscin: iiso-A2E Is i-A2E
Brais Vidal,Oscar Iglesias-Menduiña,Belén Vaz et al.
Brais Vidal et al.
The stereoselective synthesis of recently discovered lipofuscin fluorophore iiso-A2E, a C3,C4-bis-polyenylpyridinium salt derived from all-trans-retinal, which has been detected in human, pig, mouse, and bovine eyes, has been completed. The...
Silicon-Assisted Ferrier Rearrangement in Preparation of C3-Silyl Glycosides [0.03%]
含硅辅剂的费里尔重排反应在C3-硅基糖苷制备中的应用研究
Pradip Das,Satya Ravi Teja Miriyala,D Srinivasa Reddy
Pradip Das
Herein, we report a Lewis acid catalyzed Ferrier rearrangement glycosylation strategy using the α-effect of C3-silylated glucal donors. The dimethylphenylsilyl group at the C3 position promotes the reaction where the unactivated free hydro...
Synthesis and Properties of Medium-Sized cis,trans-Cycloocta-1,3-diene-Pt(II) Complexes [0.03%]
中等大小的顺式、反式环辛烷-1,3-二烯基铂(II)配合物的合成与性能研究
Hayate Kinouchi,Tomohiro Ito,Aki Kohyama et al.
Hayate Kinouchi et al.
cis,trans-Cycloocta-1,3-dienes (TCODs) are highly strained and elusive due to rapid 4π-electrocyclization. Here, we report the first stable isolation of cis,trans-cycloocta-1,3-dienes as Pt(II) complexes. X-ray crystallography revealed mar...
Synthesis of Keto Hexafluoro Alkyl Sulfonyl Amides Via Radical Ring-Opening Polymerization of Aryl-Substituted Vinyl Cyclohexafluoropropane-1,3-bis(sulfonyl)amides Followed by Hydrolysis [0.03%]
通过自由基开环聚合及水解合成酮亚氨基六氟异亚丙基磺酰胺类化合物
Takuji Kawamoto,Moeri Terauchi,Tetsushi Yamasaki et al.
Takuji Kawamoto et al.
The radical reaction of aryl-substituted vinyl cyclohexafluoropropane-1,3-bis(sulfonyl)amides (c-HFSI) followed by hydrolysis affords novel fluoroalkyl compounds. The key process in this reaction is the radical addition of c-HFSI to vinyl t...
Catalytic Asymmetric Benzoin Condensation for the Synthesis of Natural Products and Their Analogs [0.03%]
用于天然产物及其类似物合成的苯偶姻缩合反应的不对称催化合成方法研究进展
Hikaru Abe,Kazushige Sasaki,Chiharu Sakashita et al.
Hikaru Abe et al.
Catalytic enantioselective benzoin condensation conditions that are potentially useful for the total synthesis of cycloimidamicins and structure-activity relationship studies of these natural products were developed. A triazole-based NHC ca...