Evanescent Wave-Based Photonic Biosensors for the Design and Evaluation of Advanced Cancer Immunotherapies [0.03%]
基于倏逝波的光子生物传感器在先进癌症免疫疗法的设计和评估中的应用
César S Huertas,Laura M Lechuga,Maria Soler
César S Huertas
Personalized immunotherapies hold great promise for correcting cellular dysfunction, inhibiting tumor growth, and even achieving durable cancer eradication. However, conventional analytical methods used to design and evaluate immunotherapie...
Real-Time Compositional Monitoring of Sputtered Li3PO4 Electrolyte Films via In Situ Optical Emission Spectroscopy [0.03%]
基于原位光学发射光谱的磁控溅射固态电解质Li3PO4薄膜实时成分监测研究
Susumu Imashuku
Susumu Imashuku
Lithium phosphate (Li3PO4) is a key solid electrolyte for all-solid-state thin-film batteries. Although sputtering enables high-throughput film deposition, precise compositional control is essential because ionic conductivity is highly sens...
Feedback-Guided SERS-Photothermal Patch for Maintaining Redox Homeostasis in Diabetic Foot Ulcers [0.03%]
基于反馈的SERS-光热贴片以维持糖尿病足溃疡氧化还原稳态
Jun Cao,Wen-Tao Yang,Dan Cao et al.
Jun Cao et al.
Excessive oxidative stress and chronic inflammation are key obstacles to diabetic foot ulcer (DFU) healing. However, indiscriminate scavenging of reactive oxygen species (ROS) can disrupt physiological redox signaling that supports tissue r...
High-Throughput In Situ Total Internal Reflection Imaging for Visualizing, Qualitatively Screening, and Quantitatively Evaluating Hydrogen Evolution Catalysts [0.03%]
高通量原位全内反射成像技术可视化、定性筛选及量化评估析氢催化剂
Hao Lin,Zixin Wu,Qi Yang et al.
Hao Lin et al.
The advancement of hydrogen energy is an urgent necessity for the global energy transition and the realization of carbon neutrality. In water electrolysis, the development of novel catalysts is pivotal, while continued innovation in in situ...
YOLO-PeakDetect: A Convolutional Neural Network for Automatic Analysis of Irregular Bands in Gel Electrophoresis [0.03%]
基于卷积神经网络的凝胶电泳不规则条带自动分析方法_YOLO-PeakDetect
Shuai Qi,Yaoguo Wang,Yuxing Wang et al.
Shuai Qi et al.
Gel electrophoresis (GE) is a critical tool in the fields of molecular biology and biopharmaceuticals. However, the current analysis software requires extensive manual adjustments and cannot accurately determinate particle-like bands of vir...
Zhijin Shang,Yashan Fan,Shuai Shi et al.
Zhijin Shang et al.
A dual-path excitation multiquartz-enhanced photoacoustic spectroscopy (DE-M-QEPAS) sensor was reported for trace gas detection. The system employs a custom multipass cell (MPC) with a pentagonal star-shaped spot pattern, creating dual acou...
LCMS-Net: Deep Learning for Raw High Resolution Mass Spectrometry Data Applied to Forensic Cause-of-Death Screening [0.03%]
基于深度学习的 raw 高分辨质谱数据法医死因筛查方法研究-LCMS-Net
Lisa M Menacher,Liam J Ward,Fredrik Heintz et al.
Lisa M Menacher et al.
Current preprocessing workflows for untargeted metabolomics using liquid chromatography-high resolution mass spectrometry (LC-HRMS) are time-consuming and require significant domain knowledge. Furthermore, they lack reproducibility or may f...
Quantitative and Visual Detection of Pseudouridine at Specific Sites Using Bisulfite-Assisted Rolling Circle Amplification [0.03%]
利用焦磷酸测序和环介导等温扩增技术特定位点假尿嘧啶的定量及可视化检测
Xiumin Liu,Jiehua Li,Xiaoyang Duan et al.
Xiumin Liu et al.
Pseudouridine (Ψ) is a prevalent RNA modification whose site-resolved quantification is critical for understanding epitranscriptomic regulation. We present pseU-SCOPE, a ligation-assisted rolling circle amplification (RCA) assay that conve...
Development of an Anti-Immunocomplex Antibody and Non-competitive Immunoassay for the Detection of Testosterone [0.03%]
一种用于检测睾丸激素的抗免疫复合物抗体和非竞争性免疫测定法的发展
Ida Bäckström,Urpo Lamminmäki,Etvi Juntunen et al.
Ida Bäckström et al.
Accurate and sensitive quantification of testosterone using simple, high-throughput, and low-cost methods has remained a longstanding analytical challenge, despite the issue being highlighted by the endocrinology community more than a decad...
Laser-Induced Graphite Multi-Ion Sensor for Real-Time Assessment of Fucoxanthin Therapy in Alcoholic Liver Disease [0.03%]
激光诱导石墨多离子传感器实时评估褐藻素治疗酒精性肝病的效果
Xu Zhong,XiaoBo Liu,Bing Yin et al.
Xu Zhong et al.
Oxidative stress has been recognized as a pivotal mechanism for disrupting cellular ion homeostasis and contributes to the pathogenesis of associated conditions, including alcoholic liver disease (ALD). The real-time and accurate detection ...