Atg4B-Activated Near-Infrared Nanoprobe for Precise Imaging of Autophagy In Vivo [0.03%]
一种活体精准成像自噬的ATG4B激活型近红外纳米探针
Xiaotong Cheng,Tiantian Xia,Guowei Liang et al.
Xiaotong Cheng et al.
Autophagy plays a crucial role in maintaining cellular homeostasis, and its dysregulation is implicated in various diseases. High-precision imaging of autophagy activity in deep tissues is vital for elucidating the mechanisms of autophagy-r...
Hydrogen Bonding-Based SERS Method for the Ultrahigh-Sensitive Detection of Nanoplastics in Water [0.03%]
基于氢键的SERS方法用于水中共聚物纳米塑料的超灵敏检测
Jun-Jie Yu,Cheng-Ye Xi,Han-Bin Xu et al.
Jun-Jie Yu et al.
Surface-enhanced Raman spectroscopy (SERS) has emerged as a promising analytical tool for environmental risk assessment in recent years. However, it is still a challenge to achieve ultrahigh sensitive detection of nanoplastics. Herein, we p...
Self-On Aptasensor Based on Interface Oxidation-Induced H2O2 Etching Strategy for Ultrasensitive Detection of Myogenin [0.03%]
基于界面氧化诱导H2O2刻蚀策略的自开aptasensor超灵敏检测肌源性蛋白质(Myogenin)
Yating Su,Xianzhen Song,Jia Wang et al.
Yating Su et al.
Rhabdomyosarcoma (RMS), a highly malignant tumor that is more common in children, has a high mortality rate. So far, there have been few reports on the early diagnosis of RMS. As an effective biomarker for RMS, the serum level of myoglobin ...
Unveiling the Neglected Role of Silver Ions' Leaching for Recovered Functionality of Carboxylate SAMs on Ag [0.03%]
揭示银离子溶出对羧酸盐自组装单分子层在银表面重构作用的 neglected 作用
Bohan Shan,Yunhan Hu,Tongzhou Xu et al.
Bohan Shan et al.
The full release of surface-enhanced Raman spectroscopy (SERS) potential relies on modification of the substrate surface. However, chemical functionalization on silver substrates has, in some cases, resulted in anomalous behaviors that are ...
UCL-MetIsoLib: A Public High-Resolution Tandem Mass Spectrometry Library for HILIC-Based Isomer-Resolved Profiling of Glycolysis, Central Carbon Metabolism, and Beyond in Urine, Plasma, Tissues, Cells, and Patient-Derived Organoids [0.03%]
UCL-异构体库：用于基于亲水作用色谱法（HILIC）解析尿液、血浆、组织、细胞和患者衍生器官中糖酵解、中心碳代谢及更多代谢产物的高分辨率串联质谱库
Kristian Serafimov,Maria Virginia Giolito,Sébastien Ibanez et al.
Kristian Serafimov et al.
We present UCL-MetIsoLib, a publicly accessible high-resolution tandem mass spectrometry (HRMS/MS) library developed for HILIC-based, ion-pairing-free, isomer-resolved metabolomics using a bioinert UHPLC system and the Acquity Premier BEH A...
Mousumi Saha,Lingqi Qiu,Stefan Kraft et al.
Mousumi Saha et al.
The mutagenic potential of N-nitrosamines has heightened regulatory scrutiny and prompted numerous drug recalls due to their formation as impurities during pharmaceutical manufacturing. However, the simultaneous and rapid analysis of multip...
Multisignal Amplification On-Off-On Strategy via Integrating the Pore Release of Polymetallic MOFs with Perovskite QDs to Induce Dual Photocurrent Polarity Reversals for an Ultrasensitive and Wide-Range Photoelectrochemical Precise Assay [0.03%]
通过将多金属配位聚合物MOFs的孔释放与钙钛矿量子点结合实现多重信号放大的“开-关-开”策略，以引起光电流双极性倒置从而进行超灵敏和广范围的光致电化学精准分析
Weikang Wan,Jiuying Cui,Xin Xiang et al.
Weikang Wan et al.
A multisignal amplification on-off-on strategy was designed to facilitate a swift and accurate photoelectrochemical (PEC) assay of cardiac troponin I (cTnI), a biomarker universally acknowledged as the "gold standard" for diagnosing acute m...
Not Just Better Resolution: A Detailed Study of the Signal Distribution in Mid-Infrared Optical Photothermal Imaging [0.03%]
不仅仅是更好的分辨率：中红外光学光热成像信号分布的详细研究
Elisabeth Holub,Nikolaus Hondl,Sebastian Wöhrer et al.
Elisabeth Holub et al.
The spatial resolution of an imaging system is generally evaluated by analysis of the point spread function (PSF), that is, the system response to a point source in the object plane. The PSF, albeit a fundamental concept in light microscopy...
Active Radicals Enriched by the Nanoconfinement Effect Synergistically Enhance Electrochemiluminescence with a Co-Reaction Accelerator for Zearalenone Detection [0.03%]
纳米限域效应活化 radicals与共反应加速剂协同增强电致化学发光用于玉米赤霉烯酮检测
Lihui Xu,Xuena Mei,Shuang Zhou et al.
Lihui Xu et al.
The inferior electron transfer efficiency and energy dissipation during mass transport processes constitute the fundamental limitations responsible for diminished electrochemiluminescence (ECL) efficiency. To address this critical issue, a ...
Cross-wavelength Hierarchical Metamaterials-Enabled SERS-Terahertz Dual-Modal Sensor for Multipesticide Detection [0.03%]
用于多种农药检测的基于超材料的表面增强拉曼散射-太赫兹双模传感器
Lixin Ma,Ruiyun Zhou,Xiaonan Yang et al.
Lixin Ma et al.
Surface-enhanced Raman scattering (SERS) technique offers detailed chemical structure information on molecules and has been widely applied in the detection of chemical pesticide molecules. The molecular structures of different pesticides va...