Single-cell transcriptomic profiling reveals distinct tumor microenvironments in HPV-associated penile squamous cell carcinoma [0.03%]
单细胞转录组分析揭示了与HPV相关的阴茎鳞状细胞癌的不同肿瘤微环境
Lianbang Zhu,Deyun Shen,Jiahao Zhou et al.
Lianbang Zhu et al.
Background: Penile squamous cell carcinoma (PSCC) is a rare yet potentially lethal malignancy, often resulting in devastating disfigurement, with a 5-year survival rate of only ∼50%. Human papillomavirus (HPV) infection ...
HPV-associated squamous cell carcinoma in situ arising from urethral caruncle: A case of the unusual occurrence in the common urogenital lesion [0.03%]
与人乳头瘤病毒相关的尿道息肉原位鳞状细胞癌一例罕见的泌尿生殖系统常见病变中的异常情况报告
Jungsup Byun,Nora Jee-Young Park,An Na Seo et al.
Jungsup Byun et al.
Introduction and importance: Urethral caruncle is one of the most prevalent urethral inflammatory disease in postmenopausal females. Although urethral caruncle is neither neoplastic nor preneoplastic, there have been rare...
Assessment of Nectin4-Expression in Vulvar Squamous Cell Carcinomas (VSCC): correlation with HPV-associated and HPV-independent Molecular Subtypes [0.03%]
评估外阴鳞状细胞癌(VSCC)中nectin4的表达：与HPV相关和非HPV独立分子亚型的相关性
Anne Kathrin Höhn,Grit Gesine Ruth Hiller,Benjamin Wolf et al.
Anne Kathrin Höhn et al.
Background: The development of antibody-drug conjugates (ADC) for cancer treatment has achieved promising results in different solid tumors and targets. Enfortumab-Vedotin (EV), a humanised anti-Nectin4-IgG1 monoclonal an...
Synchronous yet distinct HPV-associated sinonasal carcinomas on an immune-dysfunctional background [0.03%]
免疫功能障碍背景下同步发生却又互不相同的HPV相关的鼻腔和副鼻窦癌
Jerin Thomas,Peter Giannaris,Kelly Lee et al.
Jerin Thomas et al.
Human papillomavirus (HPV)-associated multiphenotypic sinonasal carcinoma (HMSC) is a relatively new classification of head and neck carcinomas that displays histological combinations of multiple different neoplasms. Despite their high-grad...
Call for Increased Community Education Regarding Common HPV-Associated Cancers Within the Urban Safety-Net Hospital Population [0.03%]
呼吁加强对城市安全医院人群中与HPV相关的常见癌症的社区教育
Ishita Rai,Ekta Karkala,Ruchita Borgaonkar et al.
Ishita Rai et al.
While oropharyngeal and cervical cancer rates declined in the 1980s, incidence and mortality rates from both cancers have increased annually in the last two decades. The incidence of oropharyngeal cancer has now surpassed that of cervical c...
EdgeNeXt-SEDP for cervical adenocarcinoma HPV-associated and non-HPV-associated diagnosis and decision support [0.03%]
用于宫颈腺癌HPV相关和非HPV相关诊断和支持的EdgeNeXt-SEDP模型
Qi Chen,Hao Wang,Hao Zhang et al.
Qi Chen et al.
Aims: Adenocarcinoma of the uterine cervix exhibits substantial biological and histological heterogeneity, with subtype-specific differences in prognosis and therapeutic response. Conventional classification-based on hist...
Emerging nanotherapeutics for HPV-associated cancers: current advances, challenges, and future directions [0.03%]
人乳头瘤病毒相关癌症纳米药物疗法的最新进展、挑战及未来方向
Ujjawal Sharma,Himanshu Shekhar,Bunty Sharma et al.
Ujjawal Sharma et al.
Human Papillomavirus or HPV are viruses belonging to the family Papillomaviridae, these have double-stranded circular DNA. HPV is among the most common sexually transmitted infections which affect over 50% of the adult population. It is als...
Elevated Risk of HPV-Associated Oropharyngeal Cancers in Husbands of Women With Anogenital Cancer [0.03%]
女性患生殖器癌症丈夫的口腔癌发病风险升高
Tuomas Lehtinen,Luayo Zhang,Kristina Sundquist et al.
Tuomas Lehtinen et al.
Introduction: Human papillomavirus (HPV) infection is associated with tonsillar and base-of-tongue squamous cell carcinomas (TSCC/BOTSCC). We evaluated the relative risk (RR) of TSCC/BOTSCC in the husbands of women with a...
Tumor Upstaging With MRI for HPV-Associated Oropharynx Cancer: Implications for De-Escalation Trials [0.03%]
人乳头瘤病毒相关性口咽癌的磁共振肿瘤重分期与治疗减量化临床试验的意义
Steven D Wren,Linda Chen,Yao Yu et al.
Steven D Wren et al.
Objectives: Human papillomavirus (HPV)-associated oropharynx cancer (OPC) requires accurate staging to guide treatment and de-escalation clinical trial enrollment. MRI provides superior soft tissue contrast and assessment...
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