Frozen section analysis in HPV-associated squamous cell carcinoma of unknown primary: Clinical and pathological considerations [0.03%]
与HPV相关的原发不明鳞状细胞癌的冷冻切片分析：临床和病理学考虑因素
Carlos M Ardila,Anny Marcela Vivares-Builes,Eliana Pineda-Vélez
Carlos M Ardila
Genomic enrichment and functional impact of TP53 and CYLD alterations in recurrent and metastatic HPV-associated head and neck cancer [0.03%]
TP53和CYLD改变在复发性及转移性HPV相关头颈部鳞癌中的基因组富集及其对功能的影响
Manu Prasad,Alex T Cheng,Marcel Mayer et al.
Manu Prasad et al.
Purpose: Recurrent and metastatic human papillomavirus-associated head and neck squamous cell carcinoma (R/M HPV+ HNSCC) remains largely incurable, with genetic drivers incompletely defined. We profiled the genetic landsc...
In Silico Design and Characterization of a Rationally Engineered Cas12j2 Gene Editing System for the Treatment of HPV-Associated Cancers [0.03%]
一种用于治疗HPV相关癌症的理性工程Cas12j2基因编辑系统的计算机设计与表征
Caleb Boren,Rahul Kumar,Lauren Gollahon
Caleb Boren
CRISPR-Cas9 systems have enabled unprecedented advances in genome engineering, particularly in developing treatments for human diseases, like cancer. Despite potential applications, limitations of Cas9 include its relatively large size and ...
Case Report: An incidentally discovered HPV-associated endocervical adenocarcinoma presenting as pseudomyxoma peritonei [0.03%]
个案报告：偶然发现与HPV有关的宫颈部腺癌并以假性腹膜瘤表现出现
Lijun Chen,Lin Sun
Lijun Chen
This case report describes a 48-year-old woman with occult HPV-associated endocervical adenocarcinoma (Silva pattern B) presenting as bilateral ovarian metastases and pseudomyxoma peritonei-like gelatinous ascites, despite normal cervical m...
Trends in the incidence of HPV-associated anal cancer by risk group, 1990-2019: A population-based cohort study in British Columbia, Canada [0.03%]
基于人群的队列研究：1990年至2019年期间，加拿大不列颠哥伦比亚省各风险群体中HPV相关肛癌发病率的变化趋势（1990至2019年的HPV关联性肛癌发病变化趋势的人群为基础的队列研究）
Amit K Gupta,Aidan Ablona,Theodora B Consolacion et al.
Amit K Gupta et al.
Background: Anal squamous cell carcinoma, caused by human papillomavirus disproportionately affects people living with HIV (PLWH), particularly gay, bisexual, and other men who have sex with men (GBM). New guidelines reco...
[Adjuvant de-escalation versus standard treatment in HPV-associated oropharyngeal carcinoma: the phase III MC1675 trial demonstrates a reduction of long-term toxicity and defines the limits of uniform dose deintensification] [0.03%]
HPV相关型口咽癌序贯放化疗降级治疗与标准治疗的多中心Ⅲ期临床研究：降低远期毒性及统一减量方案的局限性
Philipp Schröter,Florian Stritzke,Thomas Held
Philipp Schröter
Accuracy of frozen section for HPV-Associated squamous cell carcinoma of unknown primary [0.03%]
HPV相关未知原发灶头颈部鳞癌冰冻切片的准确性分析
Sindhura Sridhar,Annie Moroco,Shravan Gowrishankar et al.
Sindhura Sridhar et al.
Introduction: Current guidelines for the management of metastatic squamous cell carcinoma of unknown primary (SCCUP) recommend submission of suspicious primary sites for frozen section analysis (FSA). This study aims to i...
Circulating tumor DNA in HPV-associated head and neck cancers - a novel clinical tool in the era of precision oncology [0.03%]
人乳头瘤病毒相关头颈癌的循环肿瘤DNA——精准肿瘤学时代的新型临床工具
M Lacek,R Lohynská
M Lacek
Background: Head and neck squamous cell carcinoma (HNSCC) represents a significant global oncological challenge with a rising incidence, particularly due to HPV-associated oropharyngeal squamous cell carcinomas (OPSCC). T...
Oncologic Outcomes of Transoral Robotic Surgery in HPV-Associated OPSCC: A Systematic Review and Meta-Analysis [0.03%]
基于HPV的口咽癌经口机器人手术的肿瘤学预后：系统回顾和Meta分析
Matthew H Cheung,Cory Hyun-Su Kim,Shaun A Nguyen et al.
Matthew H Cheung et al.
Objective: To define survival and recurrence outcomes of HPV associated oropharyngeal squamous cell carcinoma (OPSCC) following transoral robotic surgery (TORS). ...
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