Clinical validation of an HPV whole genome sequencing assay for molecular residual disease detection in HPV-associated head and neck cancer patients treated with surgery [0.03%]
用于HPV相关头颈部癌症手术治疗患者的分子残留病检测的HPV全基因组测序检测试剂盒的临床验证
Shun Hirayama,Yana Al-Inaya,Michael E Bryan et al.
Shun Hirayama et al.
Background: Surgery is a common treatment for early-stage HPV-associated head and neck squamous cell carcinoma (HPV+HNC). Selection of patients who require adjuvant treatment is based on clinicopathologic risk factors, wh...
Minimizing Chemoradiation Using a Surgical Algorithm for HPV-Associated Cancer of Unknown Primary [0.03%]
使用手术算法最小化人乳头瘤病毒相关未知原发灶癌症的化学放射治疗
Georges E Daoud,Andre J Burnham,Nikhil T Vettikattu et al.
Georges E Daoud et al.
Background: The majority of lesions originally diagnosed as cancer of unknown primary (CUP) are eventually identified as HPV-associated oropharyngeal squamous cell carcinoma. Accurate primary tumor localization can facili...
Blinded comparative evaluation of GPT-generated, online search-derived, and guideline-based answers for HPV-associated oropharyngeal cancer [0.03%]
针对人乳头瘤病毒相关口咽癌的GPT生成答案、在线搜索派生答案和指南制定答案的盲法比较评估
Sholem Hack,Rebecca Attal,Karin Geva et al.
Sholem Hack et al.
Objective: To compare the quality of online information about human papillomavirus (HPV)-associated oropharyngeal cancer generated by a large language model with content retrieved from conventional web search and authorit...
Disparities in Proton Radiation Utilization for HPV-Associated Oropharyngeal Cancer Following TORS [0.03%]
经TORS术后人乳头瘤病毒相关型口咽癌患者质子射线利用差异性分析研究报告摘要
Jane Y Tong,Vera Bzhilyanskaya,Jason K Molitoris et al.
Jane Y Tong et al.
Introduction: Racial, socioeconomic, and geographic disparities in receipt of proton radiation have been reported. Whether disparities exist for oropharyngeal squamous cell carcinoma (OPSCC) is not well studied. ...
Incidence of HPV-independent second primary malignancies following treatment of HPV-associated malignancy [0.03%]
治疗人乳头瘤病毒相关恶性肿瘤后发生独立的人乳头瘤病毒第二原发性恶性肿瘤的发病率
Sarah C Nyirjesy,Yana Al-Inaya,Selena Zhang et al.
Sarah C Nyirjesy et al.
Second primary tumors after HPV-associated oropharyngeal squamous cell carcinoma (HPV + OPSCCa) are generally assumed to share the same HPV status as the index lesion, and current pathology guidelines discourage repeat HPV testing in recurr...
Real-world multicenter study of immune checkpoint inhibitors in advanced cervical cancer across HPV-associated and HPV-independent subtypes [0.03%]
基于HPV相关和非HPV依赖型晚期宫颈癌的免疫检查点抑制剂真实世界多中心研究
Kazuhiro Ko,Mayu Fukuda,Koji Yamanoi et al.
Kazuhiro Ko et al.
Background: Cervical cancer remains a major health problem, and HPV-independent subtypes such as gastric-type adenocarcinoma carry dismal outcomes. Although immune checkpoint inhibitors (ICIs) have improved survival in la...
Complete response to nivolumab in a patient with HPV-associated squamous cell carcinoma of the anus: the predictive value of tumour-infiltrating CD8+PD-1+ T cells [0.03%]
人乳头瘤病毒相关肛门鳞状细胞癌患者接受纳武单抗治疗的完全应答：肿瘤浸润CD8+PD-1+T细胞的预测价值
Tomoki Murooka,Ken Okamura,Takanobu Kabasawa et al.
Tomoki Murooka et al.
Surgical resection outperforms chemoradiation in HPV-associated mucinous adenocarcinoma of the cervix: a SEER-based survival analysis [0.03%]
基于SEER的生存分析提示手术切除可优于放化疗成为HPV相关宫颈粘液腺癌的主要治疗手段
Jiamei Lu,Lin Lin,Xinru Li et al.
Jiamei Lu et al.
Objective: Given the rarity of human papillomavirus-associated mucinous adenocarcinoma (HPVAM) of the cervix and the lack of established clinical treatment guidelines, there is uncertainty regarding optimal clinical manag...
Trends in the burden of HPV-associated cancers in Mexico: An analysis from 2011 to 2019 [0.03%]
2011年至2019年墨西哥HPV相关癌症负担趋势分析
Juan Carlos Orengo,Ana Luiza Bierrenbach,Carlos Eduardo Aranda Flores et al.
Juan Carlos Orengo et al.
Human papillomavirus (HPV) is a major public health concern, responsible for multiple types of cancer. This study aimed to provide an overview of the burden and temporal trends of HPV-associated cancers in Mexico using national hospital dis...
When Immunity Backfires: Pembrolizumab-Induced Bilateral Pneumothorax in a Patient with Metastatic HPV-Associated Oropharyngeal Carcinoma [0.03%]
免疫功能过度所致的派姆单抗致双侧气胸：一例转移性HPV相关型口咽癌患者的病例报告
Shahzeb Saeed,Daniyal Khan,Saman Hamid et al.
Shahzeb Saeed et al.
Background: Immune checkpoint inhibitors (ICIs) are standard therapy for recurrent or metastatic head and neck squamous cell carcinoma, but unleashing antitumour immunity can trigger immune-related adverse events (irAEs)....
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