Intratumoral spatiotemporal heterogeneity of HPV DNA status in HPV-associated oropharyngeal squamous cell carcinoma with clinical record [0.03%]
具有临床记录的与HPV相关的口咽鳞癌中HPV DNA状态的时空异质性
Bokyung Ahn,Chae Won Park,Joon Seon Song et al.
Bokyung Ahn et al.
Molecular heterogeneity of HPV-associated cancers and strategies to overcome treatment resistance [0.03%]
与HPV相关的癌症的分子异质性以及克服治疗抵抗性的策略
Sara Rasouli,Weiyi Gong,Raegan Wood et al.
Sara Rasouli et al.
Human papillomavirus (HPV) is a major driver of global cancer incidence, responsible for nearly all cervical cancers and a significant proportion of oropharyngeal, anal, and other anogenital cancers. Despite the availability of effective va...
Development of a Clinical Assay to Guide Patient Therapy in HPV-Associated Head and Neck Cancer [0.03%]
开发指导HPV相关头颈癌患者治疗的临床检测方法
Sri Vemulamanda,Aditi Kothari,Loris De Cecco et al.
Sri Vemulamanda et al.
Purpose: Patients with HPV+ HNSCC have relatively favorable outcomes, standard treatments like radiation or chemoradiation frequently result in long-term toxic side effects. Appropriate patient selection has been a barrie...
Human Papillomavirus (HPV) Infected Epithelial Cells and FBLN1+ Fibroreticular Cells Govern the Immunogenic Tumor Microenvironment in HPV-Associated Oropharyngeal Squamous Cell Carcinoma [0.03%]
人乳头瘤病毒（HPV）感染的上皮细胞和FBLN1+纤维网状细胞在HPV相关性口咽鳞癌免疫原性肿瘤微环境中的作用
Doeon Gu,Joonho Shim,Soo Yoon Kim et al.
Doeon Gu et al.
Objective.: Oropharyngeal squamous cell carcinoma (OPSCC) demonstrates distinct clinical behaviors depending on human papillomavirus (HPV) status. HPV-associated OPSCC typically shows a better prognosis and response to th...
HPV-Associated Oropharyngeal Squamous Cell Carcinoma - Key Updates to the AJCC/UICC TNM9 Staging System [0.03%]
人类乳头瘤病毒相关的口咽部鳞状细胞癌-美国癌症联合委员会/国际抗癌联盟TNM9分期系统的关键更新
Mererid Evans,Shao Hui Huang,Allen S Ho et al.
Mererid Evans et al.
Assessing the burden of HPV-associated cancers in Brazil: Hospitalization and mortality trends from 2011 to 2019 [0.03%]
2011至2019年巴西HPV相关癌症的疾病负担：住院和死亡趋势分析
Cintia Irene Parellada,Ana Luiza Bierrenbach,Adriana Bittencourt Campaner et al.
Cintia Irene Parellada et al.
Human papillomavirus (HPV)-associated cancers represent a substantial public health burden. This study analyzed the national burden of hospitalization and mortality from HPV-associated cancers in Brazil between 2011 and 2019. Outcomes inclu...
Yaping Ju,Brittney K DeClerck,Saloni Walia
Yaping Ju
We report a rare case of a vulvar trichoblastoma arising synchronously with HPV-associated high-grade vulvar intraepithelial neoplasia (VIN3) in a 35-yr-old woman. Histology showed a deep dermal tumor with basaloid nests demonstrating perip...
Primary Vaginal Neuroendocrine Carcinoma: Case Report and Literature Review [0.03%]
原发性阴道神经内分泌癌的病例报道和文献复习
Yanina Nikolaus,Saroj Sigdel
Yanina Nikolaus
Keywords: atezolizumab; case report; extrapulmonary small cell carcinoma; high-grade neuroendocrine tumor; hpv-associated gynecologic malignancy; immunotherapy; insm1 immunohistochemistry; platinum–etoposide chemotherapy; primary small cell carcinoma of the vagina; vaginal neuroendocrine
Case Reports
Cureus. 2026 Jan 27;18(1):e102419. DOI:10.7759/cureus.102419 2026
Therapeutic Landscape of HPV-Associated Cancers: From Mechanisms and Conventional Approaches to Future Innovations [0.03%]
人乳头瘤病毒相关癌症的治疗格局：从机制和传统方法到未来创新疗法
Muneera Anwer,Krupa Bhaliya,Memoona Zahra et al.
Muneera Anwer et al.
Cancer remains the second leading cause of mortality worldwide. Human papillomavirus is a widespread DNA virus with well-established oncogenic potential, particularly among high-risk genotypes such as HPV16 and HPV18. Persistent infection w...
A Novel HPV-associated Mixed Neuroendocrine-Nonneuroendocrine Neoplasm of the Rectum [0.03%]
一种与HPV相关的结肠混合神经内分泌肿瘤
Ari Kassardjian,Nafis Shafizadeh,Wenjing Shi
Ari Kassardjian
High-risk human papillomavirus (HPV) is an established oncogenic driver, most commonly associated with oropharyngeal and anogenital squamous cell carcinomas. Although HPV has recently been implicated in a small subset of adenocarcinomas and...
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