Detection of Human Papillomavirus (HPV) in HPV-Associated Oropharyngeal Squamous Cell Carcinoma: A Review of Diagnostic Approach and Its Importance for the Head and Neck Oncologist [0.03%]
人乳头瘤病毒(HPV)在与HPV相关的口咽鳞状细胞癌中的检测:诊断方法及其对头颈肿瘤医生的重要性综述
Amanda J Bastien,Daniel Manzoor,Evan S Walgama et al.
Amanda J Bastien et al.
Introduction: Histopathologic assessment of surgical specimens imparts crucial information that is essential for diagnosis, treatment planning and prognostication for patients with Oropharyngeal Squamous Cell Carcinoma (O...
NSD2 upregulation is driven by high-risk HPV E6/E7 and disrupts epithelial differentiation in HPV-associated head and neck cancer [0.03%]
高危HPV E6/E7驱动的NSD2上调会干扰与HPV相关的头颈部癌症上皮分化
Lavinia Ghiani,Simona Citro,Alessandro Medda et al.
Lavinia Ghiani et al.
Galectin-1-Targeted Type-I/II Photosensitizers Activate the NF-κB Pathway to Enhance Immunity and Treat High-Risk HPV-Associated Cervical Lesions [0.03%]
靶向糖链蛋白-1的I/II型光敏剂激活NF-κB通路以增强免疫并治疗高危HPV相关宫颈病变
Qianjun Su,Hui Duan,Qiyan Li et al.
Qianjun Su et al.
Persistent infection with high-risk HPV in women can progress to cervical intraepithelial neoplasia and even cervical cancer. This study investigated the cytotoxic and immunomodulatory effects of the TBTCN-TDG photodynamic therapy (PDT) pro...
Prognostic heterogeneity of HPV-associated oropharyngeal cancer in a Taiwanese population [0.03%]
台湾人口中与HPV相关的扁桃体癌的预后异质性
Peng-Tzu Liu,Chun-Ju Chiang,Ya-Wen Yang et al.
Peng-Tzu Liu et al.
Background: Oropharyngeal squamous cell carcinoma (OPSCC) is increasing worldwide, with a well-established link to human papillomavirus (HPV). However, evidence on how lifestyle risk factors-particularly smoking, alcohol ...
Retraction and republication-De-escalation of adjuvant radiotherapy in HPV-associated oropharyngeal cancer [0.03%]
撤稿和重发:人乳头瘤病毒相关型口咽癌的辅助放疗降级疗法
The Lancet Oncology Editors
The Lancet Oncology Editors
Published Erratum
The Lancet. Oncology. 2026 Jan;27(1):e2. DOI:10.1016/S1470-2045(25)00725-9 2026
Claudin-18 expression in gastric type adenocarcinoma and HPV-associated adenocarcinoma of the uterine cervix [0.03%]
Claudin-18在胃型腺癌和HPV相关宫颈腺癌中的表达
Nobuko Yasutake,Yuki Yokawa,Takehiro Tanaka et al.
Nobuko Yasutake et al.
Aims: Claudin-18 (CLDN18) is both a marker for the gastric phenotype and a therapeutic target. However, little is known about its immunoexpression in endocervical adenocarcinomas (ECAs), particularly as detected using the...
Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer [0.03%]
HPV相关子宫恶性肿瘤发病的延迟:与宫颈癌相比的七个病理致病因素
Anda Lorena Dijmărescu,Ioana Victoria Camen,Maria Magdalena Manolea et al.
Anda Lorena Dijmărescu et al.
Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explai...
A B cell-IgA-epithelial axis enhances antitumor immunity and improves outcome in HPV-associated penile squamous cell carcinoma [0.03%]
B细胞-IgA-上皮轴增强HPV相关阴茎鳞状细胞癌抗肿瘤免疫并改善预后
Tao Tao,Lianbang Zhu,Deyun Shen et al.
Tao Tao et al.
Penile squamous cell carcinoma (PSCC) is a rare, aggressive malignancy, with HPV driving approximately 50% of cases and correlating with improved outcomes. In this study, we perform single-cell RNA sequencing on tumor microenvironment (TME)...
Spatial analysis of HPV-associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression [0.03%]
空间分析表明与宫颈癌进展相关的HPV相关宫颈上皮内瘤样组织具有不同的免疫特征
Gianna Pavilion,Hani Vu,Zherui Xiong et al.
Gianna Pavilion et al.
Cervical cancer remains the fourth most common cancer affecting women worldwide, and incidences of other HPV-related cancers continue to rise. For the development of effective prevention strategies in high-risk patients, we aimed to better ...
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