Cedar virus biology and its applications as a surrogate for highly pathogenic henipaviruses [0.03%]
雪松病毒的生物学及其作为高度病原性亨尼帕病毒替代物的应用
Ahmad Jawad Sabir,Lijun Rong,Christopher C Broder et al.
Ahmad Jawad Sabir et al.
Nipah Virus (NiV) and Hendra Virus (HeV), are the prototype species of the genus Henipavirus and are highly pathogenic agents capable of causing fatal diseases in both animals and humans. Both NiV and HeV are classified as biosafety level-4...
The role of colonic microbiota amino acid metabolism in gut health regulation [0.03%]
结肠菌群氨基酸代谢在肠道健康调节中的作用
Youli Chen,Jing-Yuan Fang
Youli Chen
The human gut microbiota plays a critical role in maintaining host homeostasis through metabolic activities. Among these, amino acid (AA) metabolism by the microbiota in the large intestine is highly heterogeneous and relevant to host healt...
Rui-Jin Ji,Mu-Yao Wang,Ying Zhang
Rui-Jin Ji
The ability to recognize antigen epitope is crucial for generating an effective immune response. By engineering these epitopes, researchers can reduce on-target/off-tumor toxicity associated with targeted immunotherapy. Recent studies indic...
Inflammatory signatures of microglia in hypercortisolemia-related depression [0.03%]
高皮质醇血症相关抑郁小胶质细胞炎症表型及功能重塑机制研究
Yanxiang Zhao,Yingying Huang,Zhangyuzi Deng et al.
Yanxiang Zhao et al.
[This corrects the article DOI: 10.1016/j.cellin.2022.100030.][This corrects the article DOI: 10.1016/j.cellin.2023.100089.][This corrects the article DOI: 10.1016/j.cellin.2022.100016.][This corrects the article DOI: 10.1016/j.cellin.2022....
Published Erratum
Cell insight. 2025 Jan 11;4(2):100225. DOI:10.1016/j.cellin.2024.100225 2025
Progress in photoreceptor replacement therapy for retinal degenerative diseases [0.03%]
视网膜退行性疾病光受体替代治疗研究进展
Yuxin Du,Yin Shen
Yuxin Du
Retinal degenerative diseases encompass a diverse range of eye conditions that result in blindness, many due to photoreceptor dysfunction and loss. Regrettably, current clinical treatments are frequently not overly effective. However, photo...
The cell autonomous and non-autonomous roles of itaconate in immune response [0.03%]
衣康酸在免疫反应中的自主和非自主作用
Chao Chen,Xinjian Li
Chao Chen
Itaconate which is discovered as a mammalian metabolite possessing antimicrobial and immunoregulatory activity has attracted much attention in the field of immunometabolism. Itaconate is synthesized by myeloid cells under conditions of path...
APC orchestrates microtubule dynamics by acting as a positive regulator of KIF2A and a negative regulator of CLASPs [0.03%]
APC通过正向调节KIF2A和负向调节CLASP调控微管动力学
Yong Wang,Xinping Liu,Zheng Liu et al.
Yong Wang et al.
Tumor suppressor protein Adenomatous polyposis coli protein (APC) is an EB-binding and microtubule (MT) plus end-tracking protein; however, how exactly APC regulates MT dynamics remains elusive. Here, we show that in LLC-PK1 cells, APC and ...
Ke-Jing Li,Lei Qi,Ying-Xuan Zhu et al.
Ke-Jing Li et al.
While genomic alterations are fundamental to biological evolution, enabling adaptation and diversity, they can also result in detrimental outcomes, such as the development of genetic diseases including cancer. The budding yeast Saccharomyce...
Transcripts derived from the neocortical enhancer of Ctnnb1 promote the enhancer-promoter interaction and maintain Ctnnb1 transcription [0.03%]
由Ctnnb1的新皮层增强子衍生的转录本促进增强子-启动子相互作用并维持Ctnnb1转录
Chen Zhao,Liang Wang,Junbao Wang et al.
Chen Zhao et al.