CXCL4 and CXCL4L1 activate human macrophage via TLR4 signaling to modulate inflammatory responses
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The chemokine CXCL4 activates human monocytes/macrophages and contributes to the pathogenesis of inflammatory and fibrotic diseases. However, the receptor of CXCL4, CXCR3, is not expressed in human monocytes/macrophages. Thus, signaling pathways and receptors ... ...
