Generation of Nano-Antibodies Targeting the SNMP1 Membrane Receptor of Spodoptera littoralis Using Extracellular Vesicles [0.03%]
使用细胞外囊泡生成针对Spodoptera littoralis SNMP1膜受体的纳米抗体
Alexis Dogliani,Laura Fradale,Céline Valeille et al.
Alexis Dogliani et al.
Handling membrane proteins (MPs) in their native environment is crucial for ensuring proper folding and stability. Extracellular vesicles (EVs) offer a superior alternative to detergents and artificial lipid environments. Expressing recombi...
Beyond miRNA Cargo Profiles: Anti-Inflammatory Roles of Extracellular Vesicle-Enriched miRNAs Derived From Human Intervertebral Disc Cells Unveiled by Functional Testing [0.03%]
超越miRNA载荷谱型：功能性试验揭示人类椎间盘细胞衍生的外泌体富集的miRNA的抗炎作用
Li Li,Aiwei Sun,Saber Ghazizadeh et al.
Li Li et al.
Intervertebral disc (IVD) degeneration is a leading cause of chronic low back pain and a major contributor to global disability. Understanding the molecular mechanisms underlying this condition is essential for developing targeted therapies...
Glioblastoma Cells Expressing Oncogenic EGFR Release Multiple Extracellular Vesicle Subpopulations Positive or Negative for EGFR [0.03%]
表达致癌表皮生长因子受体的胶质母细胞瘤细胞释放多种带有或不带EGFR的 extracellular vesicle 子群
Elham Pishavar,Fereshteh Shojaei-Ghahrizjani,Brian Meehan et al.
Elham Pishavar et al.
Extracellular vesicle (EV) heterogeneity is well documented but poorly defined. This is especially important in cancer where EVs serve as carriers of unique oncogenic macromolecules that can be transferred to recipient cells or targeted for...
Ultracentrifugation and Ultrafiltration Differentially Alter the Composition and Functionality of the Biomolecular Corona of Extracellular Vesicles [0.03%]
超速离心与超滤技术如何改变细胞外囊泡生物分子冠的组成和功能性的研究
Frederic St-Denis-Bissonnette,Hala Halabi,Marybeth Creskey et al.
Frederic St-Denis-Bissonnette et al.
While extracellular vesicles (EVs) are increasingly recognized for their diagnostic and therapeutic potential, many unknowns remain. An emerging and important concept in EV biology is the EV biomolecular corona, a dynamic layer of absorbed ...
A One-Step Workflow for Size-Based Separation of Extracellular Vesicles With Integrated Surface Marker Detection [0.03%]
一步式 workflow 基于尺寸的分离外泌体及其表面标志物检测
Lien Lippens,Niké Guilbert,Sofie Van Dorpe et al.
Lien Lippens et al.
Extracellular vesicles (EVs) are released by diverse cell types in biofluids and are increasingly studied in liquid biopsies as diagnostic and prognostic biomarkers for various diseases, including cancer. Typically, the analysis of EV-assoc...
Proteomic Epithelial-To-Mesenchymal Transition Signature in Fetoplacental Small Extracellular Vesicles of Early-Onset Preeclampsia [0.03%]
早发子痫前期胎盘外泌体蛋白质组上皮间质转化标志物的筛选及验证研究
Michaela Stoiber,Monika Horvat Mercnik,Birgit Hirschmugl et al.
Michaela Stoiber et al.
Preeclampsia (PE), a hypertensive disorder in pregnancy, is linked to placental vascular remodelling, increasing risks of foetal growth restriction and long-term offspring health problems. The role of fetoplacental endothelial cell-derived ...
Small Extracellular Vesicles in Gestational Diabetes Mellitus: Current Landscape and Emerging Diagnostic Horizons [0.03%]
妊娠期糖尿病中小细胞外囊泡的现状和新兴诊断前景
Mai Ahmed,Dada Oluwaseyi Temilola,Mushi Matjila et al.
Mai Ahmed et al.
Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy associated with significant maternal and neonatal morbidity and mortality. Current diagnostic strategies, particularly the oral glucose tolerance test (OGTT), a...
Molecular Characterization of Extracellular Vesicles From Human B Cell Lymphomas: Methodological Comparison to Vesicles From Patient Serum [0.03%]
人B细胞淋巴瘤的外泌体分子特征及其与患者血清中外泌体的方法学比较研究
Md Nasir Uddin Badal,Tiia Koivula,Md Khirul Islam et al.
Md Nasir Uddin Badal et al.
Human B cell lymphomas represent a clinically heterogeneous disease group with lack of liquid biomarkers for specific subtype classification. Extracellular vesicles (EVs) hold promises as non-invasive biomarkers, yet their subtype-specific ...
Extracellular Vesicle Properties and Functions Are Defined by the Originating Cell's Fitness Status [0.03%]
细胞的适应状态决定其释放的细胞外囊泡的属性及功能
Stephanie Leyk,Imke Liebold,Clarissa Lanzloth et al.
Stephanie Leyk et al.
Recent studies have focused on the role of dying cells in modulating immune function and shaping the local microenvironment. Apoptotic cells release various extracellular vesicles (EVs), such as exosomes and microvesicles, and form apoptoti...
Extracellular Particles Derived From Mesenchymal Stromal Cells Reduce Pseudomonas aeruginosa Lung Infection and Inflammation in Mice [0.03%]
来源于间充质基质细胞的胞外颗粒可减轻小鼠绿脓杆菌肺部感染和炎症
Sharanya Sarkar,Roxanna Barnaby,Zachary Faber et al.
Sharanya Sarkar et al.
The World Health Organization and the U.S. Centre for Disease Control and Prevention have reported that antibiotic-resistant infections with Pseudomonas aeruginosa present a significant health risk worldwide. In the genetic disease cystic f...