Workflow for the Isolation and Characterisation of Human Milk Extracellular Vesicles (HMEVs) and Their Inflammatory Biomarker Profile [0.03%]
人乳细胞外囊泡（HMEVs）的分离和表征及其炎性生物标志物谱系的工作流程
Jose Luis Moreno-Casillas,Laura Ripoll-Seguer,Isabel Ten-Doménech et al.
Jose Luis Moreno-Casillas et al.
Human milk extracellular vesicles (HMEVs), secreted by mammary epithelial cells, are enriched in bioactive molecules that support intestinal epithelial integrity. Among these, oxylipins, that is, lipid mediators derived from polyunsaturated...
Angiogenic Potential of Small Extracellular Vesicles Produced by Stimulated Mesenchymal Stromal Cells Under Hypoxic Conditions [0.03%]
低氧条件下激活的间充质基质细胞产生的小细胞外囊泡的血管生成潜能
Nada Serhal,Bertrand Brassart,Lise Nannan et al.
Nada Serhal et al.
Regenerative vascular medicine research has positioned mesenchymal stromal cells (MSCs) as a leading candidate to treat ischemic diseases. Recent studies have highlighted the emerging role of small extracellular vesicles (sEVs) produced by ...
Isolation Strategy Matters: How Tissue Processing Shapes the Composition of Placental Extracellular Vesicles [0.03%]
隔离策略很重要：组织处理如何影响胎盘细胞外囊泡的组成
Parinaz Kazemi,Elaine Lee,Daniel Dufort
Parinaz Kazemi
The placenta is a vital mediator of maternal-foetal communication, and extracellular vesicles (EVs) derived from placental tissue have gained attention as promising biomarkers of pregnancy health. Accurate molecular profiling of placental E...
Mahsa Salehi,Shukoofeh Torabi,Homeyra Seydi et al.
Mahsa Salehi et al.
Extracellular vesicles (EVs) have gained significant attention as emerging tools in diagnostics and therapeutics. Using the Gartner Hype Cycle framework, this commentary examines the current trajectory of EV research, from initial enthusias...
Immune-Related Protein and Non-Coding RNA Cargo of Extracellular Vesicles Participate in the Chronic Inflammation Induced by HIV Infection [0.03%]
与HIV感染引起的慢性炎症相关的免疫相关蛋白及非编码RNA外泌体递送机制研究
Humberto Doriguêtto Gravina,Ricardo Cardoso Castro,Ana Margarida Gonçalves et al.
Humberto Doriguêtto Gravina et al.
Extracellular vesicles (EVs) promote intercellular communication, playing a key role in the secondary immune-related pathologies driven by chronic inflammation in people living with HIV (PLWH). To identify molecular components within large ...
Expanding Horizons: Next-Generation and Interdisciplinary Advances in the Applications of Extracellular Vesicles [0.03%]
horizon：外泌体下一代及交叉学科应用进展
Esperanza González,Juan Manuel Falcón-Pérez
Esperanza González
Extracellular vesicles (EVs) are increasingly recognized as universal mediators of communication in nature across all domains of life and as versatile tools with roles spanning a wide range of industries. Although EVs have been extensively ...
Correction to Quantitative Fluorescent Nanoparticle Tracking Analysis and Nano-Flow Cytometry Enable Advanced Characterization of Single Extracellular Vesicles [0.03%]
定量荧光纳米颗粒追踪分析及nano-flow cytometry技术的修正使单个细胞外囊泡的高级表征成为可能
[This corrects the article DOI: 10.1002/jex2.70031.]. © 2025 The Author(s). Journal of Extracellular Biology published by Wiley Periodicals LLC on behal...
Published Erratum
Journal of extracellular biology. 2025 Dec 8;4(12):e70103. DOI:10.1002/jex2.70103 2025
Oral Delivery of Semaglutide and Tirzepatide Using Milk-Derived Small Extracellular Vesicles [0.03%]
利用牛奶源小细胞外囊泡口服递送司美格鲁肽和 tirzepatide
Yuefei Zhang,Jianyi Han,Wei Wu et al.
Yuefei Zhang et al.
Therapeutic proteins and peptides have revolutionized modern biomedicine, but their oral delivery is limited by gastrointestinal degradation and barriers. Small extracellular vesicles (sEVs), which are resistant to biochemical degradation a...
Single-Cell Analysis of L-Myc Expressing Neural Stem Cells and Their Extracellular Vesicles Revealed Distinct Progenitor Populations With Neurogenic Potential [0.03%]
单细胞分析L-Myc表达神经干细胞及其外泌体发现了具有神经生成潜能的不同祖细胞群
Patrick Pirrotte,Yate-Ching Yuan,Nathaniel P Hansen et al.
Patrick Pirrotte et al.
Neural stem cell (NSC)-based therapies offer a promising strategy to promote brain repair by delivering neurotrophic factors, supporting cell replacement, and stimulating endogenous neurogenesis following injury. While numerous studies have...
Characterization of HIV-1 Particles Co-Purified With Three Extracellular Vesicle Subtypes From the Raji CD4 DCIR Cell Line, a Hybrid Model of CD4 T Cells and Dendritic Cells [0.03%]
来自Raji CD4 DCIR细胞系的三种胞外囊泡亚型共纯化的HIV-1颗粒的表征，一个CD4 T细胞和树突状细胞杂交模型
Julien Boucher,Alyssa Rousseau,Caroline Gilbert
Julien Boucher
HIV-1 proteins and RNA are incorporated into extracellular vesicles (EVs) via the EV biogenesis machinery. Due to their similar size and content, EVs and HIV-1 particles are hard to separate, and current purification methods often overlook ...