Ablation of Mea6/cTAGE5 in oligodendrocytes significantly impairs white matter structure and lipid content [0.03%]
MEA6/cTAGE5缺失影响少突胶质细胞的脂质含量和髓鞘形成
Tiantian Ma,Wei Mao,Shaohua Zhang et al.
Tiantian Ma et al.
Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons. Abnormal myelin sheath is associated with many neurological diseases. Meningioma-expressed antigen 6 (Mea6)/cutaneous T cell lymphoma-associated an...
Camille Allard,Daniela Cota
Camille Allard
A new journal for a new age [0.03%]
一个新时代的新期刊
Peng Li,John R Speakman
Peng Li
Xu Wang,Shen-Ying Liu,Guo-Sheng Hu et al.
Xu Wang et al.
Brown adipose tissue (BAT) plays a key role in thermogenesis during acute cold exposure. However, it remains unclear how BAT is prepared to rapidly turn on thermogenic genes. Here, we show that damage-specific DNA binding protein 1 (DDB1) m...
Hao Wu,Ling-Ling Chen
Hao Wu
Fucheng Dong,Wei Li
Fucheng Dong
Temporal patterns of energy intake and cognitive function and its decline: a community-based cohort study in China [0.03%]
能量摄入的时间模式与认知功能及其衰退的社区纵向队列研究
Hui Chen,Yang Tao,Min-Dian Li et al.
Hui Chen et al.
Peixue Xia,Liankui Zhou,Jialiang Guan et al.
Peixue Xia et al.
Animals respond to mitochondrial perturbation by activating the mitochondrial unfolded protein response (UPRmt) to induce the transcription of mitochondrial stress response genes. In Caenorhabditis elegans, activation of UPRmt allows the an...
Impaired SERCA2a phosphorylation causes diabetic cardiomyopathy through impinging on cardiac contractility and precursor protein processing [0.03%]
钙 ATP 酶 2 抗磷导致糖尿病心肌病：影响心脏收缩和前体蛋白的加工
Chao Quan,Sangsang Zhu,Ruizhen Wang et al.
Chao Quan et al.
Diabetic cardiomyopathy (DCM) is currently a progressive and nonstoppable complication in type 2 diabetic patients. Metabolic insults and insulin resistance are involved in its pathogenesis; however, the underlying mechanisms are still not ...
Smooth muscle AKG/OXGR1 signaling regulates epididymal fluid acid-base balance and sperm maturation [0.03%]
平滑肌AKG / OXGR1信号传导调节附睾液酸碱平衡和精子成熟
Chang Xu,Yexian Yuan,Cha Zhang et al.
Chang Xu et al.
Infertility is a global concern attributed to genetic defects, lifestyle, nutrition, and any other factors that affect the local metabolism and niche microenvironment of the reproductive system. 2-Oxoglutarate receptor 1 (OXGR1) is abundant...