Hao Wu,Ling-Ling Chen
Hao Wu
Fucheng Dong,Wei Li
Fucheng Dong
Temporal patterns of energy intake and cognitive function and its decline: a community-based cohort study in China [0.03%]
能量摄入的时间模式与认知功能及其衰退的社区纵向队列研究
Hui Chen,Yang Tao,Min-Dian Li et al.
Hui Chen et al.
Peixue Xia,Liankui Zhou,Jialiang Guan et al.
Peixue Xia et al.
Animals respond to mitochondrial perturbation by activating the mitochondrial unfolded protein response (UPRmt) to induce the transcription of mitochondrial stress response genes. In Caenorhabditis elegans, activation of UPRmt allows the an...
Impaired SERCA2a phosphorylation causes diabetic cardiomyopathy through impinging on cardiac contractility and precursor protein processing [0.03%]
钙 ATP 酶 2 抗磷导致糖尿病心肌病：影响心脏收缩和前体蛋白的加工
Chao Quan,Sangsang Zhu,Ruizhen Wang et al.
Chao Quan et al.
Diabetic cardiomyopathy (DCM) is currently a progressive and nonstoppable complication in type 2 diabetic patients. Metabolic insults and insulin resistance are involved in its pathogenesis; however, the underlying mechanisms are still not ...
Smooth muscle AKG/OXGR1 signaling regulates epididymal fluid acid-base balance and sperm maturation [0.03%]
平滑肌AKG / OXGR1信号传导调节附睾液酸碱平衡和精子成熟
Chang Xu,Yexian Yuan,Cha Zhang et al.
Chang Xu et al.
Infertility is a global concern attributed to genetic defects, lifestyle, nutrition, and any other factors that affect the local metabolism and niche microenvironment of the reproductive system. 2-Oxoglutarate receptor 1 (OXGR1) is abundant...
Alessio Bevilacqua,Ping-Chih Ho,Fabien Franco
Alessio Bevilacqua
Aging represents an emerging challenge for public health due to the declined immune responses against pathogens, weakened vaccination efficacy, and disturbed tissue homeostasis. Metabolic alterations in cellular and systemic levels are also...
Jonas T Treebak
Jonas T Treebak
Light phase-restricted feeding in mice enhances exercise endurance in sedentary mice through a mechanism involving BMAL1-induced inhibition of Plin5 expression (created with BioRender.com). ...
Gregory J Anderson,David M Frazer
Gregory J Anderson
Changhong Li,Yi Zhang,Li Chen et al.
Changhong Li et al.
Glucokinase (GK) plays a pivotal role in glucose homeostasis as the glucose sensor in the pancreas and liver. Loss of function of GK results in hyperglycemia, and gain of function causes congenital hyperinsulinemic hypoglycemia. We speculat...