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Ablation of Mea6/cTAGE5 in oligodendrocytes significantly impairs white matter structure and lipid content

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Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons. Abnormal myelin sheath is associated with many neurological diseases. Meningioma-expressed antigen 6 (Mea6)/cutaneous T cell lymphoma-associated antigen 5C (cTAGE5C) p... ...