Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair [0.03%]
活化细胞核抗原单泛素化在促进Fanconi贫血介导的链间交联修复中的双重作用
Ronak Shah,Muhammad Assad Aslam,Aldo Spanjaard et al.
Ronak Shah et al.
The Fanconi anemia (FA) repair pathway governs repair of highly genotoxic DNA interstrand crosslinks (ICLs) and relies on translesion synthesis (TLS). TLS is facilitated by REV1 or site-specific monoubiquitination of proliferating cell nucl...
Influential individuals can promote prosocial practices in heterogeneous societies: a mathematical and agent-based model [0.03%]
有影响力的个体可以促进异质社会中的亲社会行为：数学和基于智能体的模型
Stefani A Crabtree,Colin D Wren,Avinash Dixit et al.
Stefani A Crabtree et al.
In this paper, we examine how different governance types impact prosocial behaviors in a heterogenous society. We construct a general theoretical framework to examine a game-theoretic model to assess the ease of achieving a cooperative outc...
Zhongpu Yue,Yi Li,Bin Yu et al.
Zhongpu Yue et al.
Leak potassium (K+) currents, conducted by two-pore domain K+ (K2P) channels, are critical for the stabilization of the membrane potential. The effect of K2P channels on motor rhythm remains enigmatic. We show here that the K2P TWK-40 contr...
Learning optimal integration of spatial and temporal information in noisy chemotaxis [0.03%]
学习在嘈杂的化学趋向性中优化时空信息的整合
Albert Alonso,Julius B Kirkegaard
Albert Alonso
We investigate the boundary between chemotaxis driven by spatial estimation of gradients and chemotaxis driven by temporal estimation. While it is well known that spatial chemotaxis becomes disadvantageous for small organisms at high noise ...
Large language models can infer psychological dispositions of social media users [0.03%]
大型语言模型可以推断社交媒体用户的心理倾向
Heinrich Peters,Sandra C Matz
Heinrich Peters
Large language models (LLMs) demonstrate increasingly human-like abilities across a wide variety of tasks. In this paper, we investigate whether LLMs like ChatGPT can accurately infer the psychological dispositions of social media users and...
Watching the Grand Ethiopian Renaissance Dam from a distance: Implications for sustainable water management of the Nile water [0.03%]
从远处观察大埃及复兴坝：对尼罗河水可持续管理的影响
Karem Abdelmohsen,Mohamed Sultan,Eugene Yan et al.
Karem Abdelmohsen et al.
Increased demands for sustainable water and energy resources in densely populated basins have led to the construction of dams, which impound waters in artificial reservoirs. In many cases, scarce field data led to the development of models ...
Valuations of target items are drawn towards unavailable decoy items due to prior expectations [0.03%]
目标物品的估值因先前预期而偏向不可用的诱饵物品
Liz Izakson,Minhee Yoo,Adam Hakim et al.
Liz Izakson et al.
When people make choices, the items they consider are often embedded in a context (of other items). How this context affects the valuation of the specific item is an important question. High-value context might make items appear less attrac...
Chiara Patricia Drolsbach,Kirill Solovev,Nicolas Pröllochs
Chiara Patricia Drolsbach
Community-based fact-checking is a promising approach to fact-check social media content at scale. However, an understanding of whether users trust community fact-checks is missing. Here, we presented n = 1,810 Americans with 36 misleading ...
Why do we think? The dynamics of spontaneous thought reveal its functions [0.03%]
我们为何思考？自发性思维的动态揭示了其功能
Judith N Mildner,Diana I Tamir
Judith N Mildner
Spontaneous thought-mind wandering, daydreaming, and creative ideation-makes up most of everyday cognition. Is this idle thought, or does it serve an adaptive function? We test two hypotheses about the functions of spontaneous thought: Firs...
Gradual ER calcium depletion induces a progressive and reversible UPR signaling [0.03%]
渐进式的内质网钙流失会诱导出渐进式且可逆的未折叠蛋白数信号反应
Ilaria Pontisso,Roberto Ornelas-Guevara,Eric Chevet et al.
Ilaria Pontisso et al.
The unfolded protein response (UPR) is a widespread signal transduction pathway triggered by endoplasmic reticulum (ER) stress. Because calcium (Ca2+) is a key factor in the maintenance of ER homeostasis, massive Ca2+ depletion of the ER is...