A signature constructed with circadian rhythm-related genes to predict the prognosis and therapy response for low-grade gliomas [0.03%]
一个由与昼夜节律相关的基因构成的低级别胶质瘤预后和治疗反应预测标志物签名模型
Yiqiang Zhou,Ruwei Ke,Ziliang Hu et al.
Yiqiang Zhou et al.
Recent studies suggest circadian rhythm-related genes are crucial for immune balance and potential therapeutic targets, but their role in low-grade gliomas (LGG) is not well understood. We analyzed their prognostic significance in glioma pr...
Novel common target genes for breast cancer and colorectal cancer: a Mendelian randomization and spatial transcriptomics study [0.03%]
乳腺癌和结直肠癌的新共同靶基因的孟德尔随机化与空间转录组学研究
Pengyu Miao,Zhaokai Zhou,Ling Zhang et al.
Pengyu Miao et al.
Introduction: Breast and colorectal cancer are a major global public health problem. Breast cancer is one of the most common cancers worldwide. Colorectal cancer is the third most common cancer and the second most common ...
Targeting the osteosarcoma immune microenvironment for improved immunotherapy and translational applications [0.03%]
靶向骨肉瘤免疫微环境以改进免疫治疗和转化应用
Jinlin Cai,Shijie Qiu,Biao Sun et al.
Jinlin Cai et al.
Comparative efficacy of Palbociclib and Everolimus with aromatase inhibitors in second line treatment of HR and HER2 negative metastatic breast cancer [0.03%]
帕博西尼与依维莫司联用芳香化酶抑制剂治疗HR和HER2阴性的二线转移性乳腺癌患者的疗效比较研究
Nadia Najafizade,Shadi Zarei,Mohammadreza Elhaie et al.
Nadia Najafizade et al.
Decoding SDCBP's role in tumor progression and immune cells infiltration: from databases to macrophage validation [0.03%]
利用数据库和巨噬细胞验证SDCBP在肿瘤进展及免疫细胞浸润中的作用机制研究
Chanyuan Zhao,Chenli Zhang,Xiaoyu Zhang et al.
Chanyuan Zhao et al.
The search for highly sensitive and specific tumor biomarkers is essential for the evaluation of prognosis and new therapeutic targets. Immune cells in the tumor microenvironment (TME) have dual roles in promoting and suppressing tumor grow...
HOMER3 and its correlation with immune-infiltrating M2 macrophages in colorectal cancer [0.03%]
HOMER3及其与结直肠癌免疫浸润M2型巨噬细胞的相关性研究
Ruirui Luan,Changjiang Yang,Xianglian Niu
Ruirui Luan
Mendelian randomization study explores the peripheral immunological characteristics of colorectal cancer [0.03%]
孟德尔随机化研究探索结直肠癌的外周免疫学特征
Chendong Yuan,Xufeng Shu,Xiaoqiang Wang et al.
Chendong Yuan et al.
Background: Colorectal cancer (CRC) is one of the most common malignancies worldwide. However, the immunological mechanisms underlying CRC pathogenesis remain unclear. This study aims to elucidate the causal relationships...
Evaluating the survival benefit of adjuvant chemotherapy based on tumor deposit status in stage II colon cancer patients from SEER database [0.03%]
基于SEER数据库II期结肠癌患者肿瘤沉积状态评估辅助化疗的生存收益
Jiabin Ye,Zhifeng Lin,Rongrong Dai et al.
Jiabin Ye et al.
Blastic plasmacytoid dendritic cell neoplasm (BPDCN): international, multi-center collaboration and global registry program [0.03%]
具髓浆细胞样树突状细胞肿瘤（BPDCN）的国际多中心合作和全球注册项目
Astghik Voskanyan,Maria Badikyan,Marina Konopleva et al.
Astghik Voskanyan et al.
Background: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare and aggressive hematologic malignancy originating from plasmacytoid dendritic cell precursors. BPDCN shares common diagnostic and clinical feature...
Single-cell transcriptomic profiling and machine learning identify S-nitrosylation-associated LAMC2 as a key prognostic driver in pancreatic cancer [0.03%]
单细胞转录组学和机器学习鉴定出一种与S-亚硝基化相关的LAMC2，并确定其为胰腺癌预后驱动因子
Chenchen Yang,Hengfa Ge,Yunfan Yin et al.
Chenchen Yang et al.
Background: Pancreatic cancer (PC) remains one of the deadliest malignancies worldwide, characterized by late diagnosis, limited therapeutic options, and dismal prognosis. Post-translational modifications (PTMs) are incre...