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Durable response to trametinib in a neurofibromatosis type 1 associated adult glioma-a case report

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Neurofibromatosis type I (NF1) is a heritable disease that may lead to the occurrence of primary central nervous system tumors, including gliomas. Treatment of NF1-associated diffuse gliomas is cumbersome due to the limited evidence and the risk of radio-induc... ...