Identification and analysis of key transcription factors in esophageal squamous cell carcinoma [0.03%]
食管鳞状细胞癌中的关键转录因子鉴定及分析
Zhe-Ran Chen,Zhi-Yuan Cheng,Si-Wei Zhou et al.
Zhe-Ran Chen et al.
Background and Objective: Over the past decade, transcription factors (TFs) have emerged as key players in various diseases. Immunotherapy has gained traction as an effective treatment, despite resistance to immune checkp...
LncRNA VIM-AS1 is a potential prognostic biomarker and effects on tumor cellular behaviors in breast cancer via impairing miR-29a-3p [0.03%]
长链非编码RNA VIM-AS1通过损害miR-29a-3p在乳腺癌预后生物标志物及对肿瘤细胞行为的影响方面具有潜在作用
Yang Yuan,Meng Wei,Linna Kong et al.
Yang Yuan et al.
Objective: The purpose of our research was to investigate the clinical significance of lncRNA VIM anti-sense 1 (VIM-AS1) and to elucidate its cellular functions in breast cancer patients. ...
Overlapping risk factors and pathogenic mechanisms in lung cancer and cardiovascular disease [0.03%]
肺癌与心血管疾病的风险因素及发病机制的相互作用
Yan Liu,Yifei Li,Haiyang Ning et al.
Yan Liu et al.
Lung cancer and cardiovascular diseases (CVDs) are leading global causes of mortality, with growing evidence suggesting a complex interplay between the two. While traditionally viewed as distinct conditions, shared risk factors and intrinsi...
Qiang Su,Yi Hu,Bin Dai
Qiang Su
Background: The pathogenesis of prostate cancer (PCa) is strongly influenced by metabolism. Thus, we explored candidate genes with metabolism-related functions that can be used to predict PCa prognosis. ...
Pu Shen,Meng Yang
Pu Shen
Breast cancer (BC), a leading cause of cancer mortality in women, involves complex molecular mechanisms including post-translational modifications (PTMs). While common PTMs are well-studied, lactylation-a novel PTM linking metabolism to epi...
Clinical performance of GAAD score, alpha-fetoprotein, and PIVKA-II in diagnosing hepatocellular carcinoma in the Vietnamese cohort [0.03%]
GAAD评分、甲胎蛋白和PIVKA-II在越南人群肝细胞癌诊断中的临床效能分析
Thuy Thi Thu Pham,Dat Tan Ho,Toan Bao Nguyen et al.
Thuy Thi Thu Pham et al.
Objective: Alpha-fetoprotein (AFP), PIVKA-II, and GAAD have been studied effectively for the early diagnosis of hepatocellular carcinoma (HCC), creating an opportunity for effective treatment, thereby improving the surviv...
Disulfidptosis mechanisms and therapeutic implications in cancer metabolic reprogramming and future perspectives [0.03%]
二硫化抑制的机制、在癌症代谢重组中的治疗意义及其未来展望
Ronghui Chen,Jianhang You,Suxia Weng et al.
Ronghui Chen et al.
Regulatory cell death exhibits distinctive advantages in cancer therapy. Among such mechanisms, disulfidptosis effectively inhibits tumor growth by inducing disulfide bond stress and subsequent rupture under particular conditions, thus demo...
Gut microbiota and urological cancers: from microecological imbalance to potential for precision therapy [0.03%]
肠道微生物群和泌尿系统癌症：从微生态失衡到精准治疗的潜力
Junfeng Cui,Hong Chen,Fengming Dong et al.
Junfeng Cui et al.
In recent years, the gut microbiota plays an important role in the occurrence and development of a variety of diseases, especially in the field of oncology, where research progress has become increasingly significant. The complex relationsh...
Multi-omics-based molecular classification of adrenocortical carcinoma predicts response to immunotherapy and targeted treatments [0.03%]
基于多组学的肾上腺皮质癌分子分型可预测免疫治疗和靶向治疗的反应性
Xingwei Jin,Xianjin Wang,Zhiyuan Wang et al.
Xingwei Jin et al.
Adrenal cortical carcinoma (ACC) is a rare and highly aggressive malignant tumor with dismal outcomes. Once metastasis occurs, the 5-year survival rate falls below 15%. Current treatment options offer LIMited benefit for advanced disease, L...
Comparing the diagnostic accuracy of pre-operative genetic testing for thyroid cancer on fine needle aspiration cytology specimens: a systematic review and meta-analysis of diagnostic accuracy [0.03%]
术前遗传检测与细针抽吸细胞学诊断甲状腺癌准确度的比较：系统综述和诊断准确性Meta分析
Xin Liao,Klaas Van Den Heede,Bruno Lapauw et al.
Xin Liao et al.