Medical, Genomic, and Evolutionary Aspects of the Peptide Sharing between Pathogens, Primates, and Humans [0.03%]
病原体，灵长类和人类之间多肽分享的医学，基因组学和进化方面的研究
Darja Kanduc,Yehuda Shoenfeld
Darja Kanduc
Comparing mammalian proteomes for molecular mimicry with infectious pathogens highlights the highest levels of heptapeptide sharing between pathogens and human, murine, and rat proteomes, while the peptide sharing level is minimal (or absen...
From Anti-EBV Immune Responses to the EBV Diseasome via Cross-reactivity [0.03%]
从抗EB病毒免疫反应到通过交叉免疫的EB病毒感染疾病组
Darja Kanduc,Yehuda Shoenfeld
Darja Kanduc
Sequence analyses highlight a massive peptide sharing between immunoreactive Epstein-Barr virus (EBV) epitopes and human proteins that-when mutated, deficient or improperly functioning-associate with tumorigenesis, diabetes, lupus, multiple...
Methylenetetrahydrofolate Reductase (MTHFR) C677T and A1298C Polymorphisms in Georgian Females with Hypothyroidism [0.03%]
格鲁吉亚女性甲状腺功能减退患者的亚甲基四氢叶酸还原酶(MTHFR) C677T和A1298C多态性研究
Tamar Kvaratskhelia,Elene Abzianidze,Ketevan Asatiani et al.
Tamar Kvaratskhelia et al.
The aim of this study was to investigate the frequency of methylenetetrahydrofolate reductase ( MTHFR) gene polymorphisms in Georgian females with hypothyroidism. Thirty-four patients and 29 healthy individuals were recruited in this study....
The Role of PON1 Variants in Disease Susceptibility in a Turkish Population [0.03%]
土耳其人群中PON1变异体在疾病易感性中的作用
Mahmoud Abudayyak,Tuğçe Boran,Rumeysa Tukel et al.
Mahmoud Abudayyak et al.
Paraoxonase 1 (PON1) enzyme plays a major role in antioxidant defense and protects the cells against reactive species. The most common PON1 Q192R and L55M polymorphisms are responsible for a wide variation of PON1 activity, which showed an ...
Utility of KRAS Gene and Clinicopathological Features in the Assessment of the Risk of Type 2 Diabetes in the Etiology of Colon Cancer [0.03%]
KRAS基因和临床病理特征在评估结肠癌发病机制中2型糖尿病风险的应用
Wedad Saeed Al-Qahtani,Ebtesam Al-Olayan,Fatimah Gh Albani et al.
Wedad Saeed Al-Qahtani et al.
Background Cancer and diabetes have a tremendous impact on health globally. This study aimed to evaluate the KRAS gene in colon cancer tissues obtained from patients with type 2 diabetes mellitus (T2DM). Materials and Methods Data from 315 ...
Xiaojuan Wang,Na Li,Wei Li et al.
Xiaojuan Wang et al.
Adverse stress influences the normal growth and development of plants. With the development of molecular biology technology, understanding the molecular mechanism of plants in response to adverse stress has gradually become an important top...
CRISPLD2 Gene Polymorphisms with Nonsyndromic Cleft Lip Palate in Indian Population [0.03%]
CRISPLD2基因多态性与印度人群中非综合征型唇裂 palate的关系
Praveen Kumar Neela,Srinivas Reddy Gosla,Akhter Husain et al.
Praveen Kumar Neela et al.
Cleft lip palate (CLP) is one of the common congenital anomalies with multifactorial etiology. Many genes are associated with its etiology. In one of the studies CRISPLD2 gene polymorphisms rs1546124, rs4783099, and rs16974880 were reported...
The Clinical Effectiveness of Preimplantation Genetic Diagnosis for Chromosomal Translocation Carriers: A Meta-analysis [0.03%]
移植前遗传学诊断在染色体易位携带者中的临床效果：一项荟萃分析
Manijeh Mahdavi,Seyedeh M Sharafi,Seyede S Daniali et al.
Manijeh Mahdavi et al.
Published data on the relationship between pregnancy outcomes of preimplantation genetic diagnosis (PGD) in translocation carriers have implicated inconclusive results. To identify potentially eligible reports, an electronic search was cond...
Meta-Analysis on the Association of C-Reactive Protein Polymorphisms with Metabolic Syndrome [0.03%]
C反应蛋白基因多态性与代谢综合征关系的meta分析
Seyedeh Maryam Sharafi,Manijeh Mahdavi,Roya Riahi et al.
Seyedeh Maryam Sharafi et al.
Polymorphisms in the C-reactive protein (CRP) genes might have crucial role in the development of metabolic syndrome (MetS). In the current comprehensive meta-analyses, we aim to provide a quantitative assessment of the association between ...