CTLA-4 (+49A/G) Polymorphism in Type 1 Diabetes Children of Sudanese Population
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Background Type 1 diabetes mellitus (T1DM) is an organ-specific T cell-mediated autoimmune disease, characterized by destruction of pancreatic islets. Cytotoxic lymphocyte antigen-4 ( CTLA-4 ) is a negative regulator of T cell proliferation, thus conferring su... ...
