Form follows function: morphology as a map of mechanisms in neurodegenerative disease pathology [0.03%]
形式服从功能:神经退行性疾病病理机制的形态学地图
Edward B Lee
Edward B Lee
Across neurodegenerative diseases, the shape and spatial organization of pathology carry rich mechanistic information. Vacuoles, spongiosis, oligodendroglial coiled bodies, dendritic dystrophic neurites, amyloid plaque compactness, and phas...
The shapes of brain waste: Mysteries of cellular remnant morphology in neurodegeneration [0.03%]
脑垃圾的形状:神经退行性病变中细胞残体形态之谜
David V Forrest
David V Forrest
This meditation with apologies by a psychiatrist who is not a neuropathologist but attends CPCs of movement disorder patients speculates about how microscopic mechanical processes produce the variety of cellular neuropathological forms, whi...
Trends in neuropathology training in Sub-Saharan Africa - current curricula, resource gaps, and the potential of virtual microscopy and telemedicine [0.03%]
东非神经病理学培训趋势-现行课程、资源差距及虚拟显微镜和远程医学的潜力
Habiblah Jagunmolu,Emmanuel Oyetola,Kamil Ajagbe et al.
Habiblah Jagunmolu et al.
Introduction: Neuropathology is important in the diagnosis of neurologic and neuro-oncologic diseases. But despite its immense importance, it remains underrepresented in medical training across different parts of Sub-Saharan Africa. Trainin...
Central nervous system schwannoma, VGLL-fused (EWSR1::VGLL1 fusion) with neuroblastoma-like cell dense areas in the frontal lobe of a young man with schwannomatosis due to a germline LZTR1 mutation [0.03%]
由于LZTR1种系突变的施万细胞瘤病患者的中枢神经系统的施万细胞瘤(EWSR1::VGLL1融合), frontal lobe 中出现类似神经母细胞瘤密集细胞区域(发生在一位年轻男性身上)
David G Munoz,Sunit Das,Ju-Yoon Yoon et al.
David G Munoz et al.
We report a central nervous system schwannoma, VGLL-fused in a young man's frontal lobe. Somatic abnormalities included an EWSR1::VGLL1 fusion, which incorporated the entire translated region of VGLL1, but excluded most domains of EWSR1. Th...
Georg Haase,Marta Margeta,Ralf Mersmann et al.
Georg Haase et al.
Histologic and molecular characterization of a MAZ::NCOA2 fusion-positive intracranial neoplasm [0.03%]
MAZ::NCOA2融合阳性颅内肿瘤的组织病理学和分子特征分析
Elliot Stalter,Claire Voyles,Leonardo F Freitas et al.
Elliot Stalter et al.
Mechanical perfusion in brain banking: methods of assessment and relationship to the postmortem interval [0.03%]
脑库机械灌注的评估方法及与死亡后间隔的关系
Gabriel A Taylor,Emma L Thorn,Claudia De Sanctis et al.
Gabriel A Taylor et al.
The mechanical perfusion of solutions through the cerebrovascular system is critical for several types of postmortem research. However, achieving consistently high-quality perfusion in this setting is challenging. Several previous studies h...
ACOX1 gain-of-function post-mortem neuropathology is distinct from ACOX1 loss-of-function: case report and literature review [0.03%]
乙酰辅酶A氧化酶1功能获得性死后神经病理改变与该酶功能缺失型的不同:病例报告和文献综述
Zita Hubler,Kaleigh Filisa Roberts,Nima Sharifai et al.
Zita Hubler et al.
A malignant choroid plexus tumor with heterologous differentiation and BAP1 deletion suggesting choroid plexus blastoma [0.03%]
具有异质性分化的恶性脉络丛肿瘤伴有BAP1基因缺失提示脉络膜皮质母细胞瘤
Arnault Tauziède-Espariat,Alice Métais,Léa Guerrini-Rousseau et al.
Arnault Tauziède-Espariat et al.