Alzheimer's disease in the Plasticene era: a clinicopathological update on the dual sequestration of amyloid and tau as hijacked innate immune responses
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Background: The defining neuropathological hallmarks of Alzheimer's disease (AD)-amyloid-β (Aβ) plaques and tau neurofibrillary tangles (NFTs)-are now understood to exist along a continuum with brain aging, yet their fundamental trigger in sporadic disease ... ...
