Synthetic Access to Fluorinated Analogs of a Known Streptococcus pneumoniae Type 14 Glycotope [0.03%]
合成获得已知肺炎链球菌血清型14甘露糖型的氟化类似物
Maximilian Reindl,Andreas Baumann,Anja Hoffmann-Röder
Maximilian Reindl
For the first time, we present fluorinated analogs of Streptococcus pneumoniae serotype 14 (SPn14)-specific tetrasaccharide antigens originating from the repeating unit {6)-[β-d-Galp-(1→4)-]-β-d-GlcpNAc-(1→3)-β-d-Galp-(1→4)-β-d-Glcp-...
The "Missing Link", Allostery and SynergismHosting of Metal Cations by Regular and Partial Cone Calix[4]arene Isomers [0.03%]
“缺电子链”，别位相互作用和协同效应——规则型及部分锥型杯芳烃异构体对金属离子的夹持作用
Matija Modrušan,Nikola Cindro,Marija Cvetnić et al.
Matija Modrušan et al.
The influence of the tetra-O-2-oxopropyl-substituted calix-[4]-arene conformation on its binding affinity toward first- and second-group metal cations, as well as on the solvent molecule (acetonitrile or methanol) inclusion in the calixaren...
[3 + 2] Cycloadditions of Tertiary Amine N‑Oxides and Azoarenes as a Route to Substituted 1,2,4-Triazolidines [0.03%]
三级胺-N-氧化物和azoarenes的[3+2]环加成反应生成取代的1,2,4-三唑烷的新方法
Nicholas A Frankos,Malavika S Nair,Aiden M Lane et al.
Nicholas A Frankos et al.
We have developed a synthesis of 29 novel 1,2,4-triazolidines using tertiary amine N-oxides and a wide range of substituted azoarenes. Our method utilizes a base-mediated [3 + 2] cycloaddition, starting from either commercially available or...
More than Catalyst Recycling: Tuning Synthetic Photocatalytic Processes via Heterogenization on Silica and Alumina [0.03%]
不止于多相光催化剂的回收：通过负载调节硅胶和氧化铝上的催化性能
Zacharias Amara,Pierre Zimberlin,Augustin Pirenam Atakpa et al.
Zacharias Amara et al.
The heterogenization of homogeneous photocatalysts on inert supports such as silica and alumina offers more than improved recyclability. Unlike semiconducting supports such as titanium dioxide, which can alter the photocatalyst behavior thr...
Yaroslav Melnyk,Oleksandr S Liashuk,Oleksandr Horulya et al.
Yaroslav Melnyk et al.
A practical and scalable protocol for the deoxyfluorination of hydroxyalkyl-substituted aryl- and alkenylboronates was developed. The optimized conditions (combining Deoxo-Fluor with TEA·3HF as the reagents and substrate preconversion to t...
The Combined Role of Silanols and Oxidative Stress in Determining Engineered Stone Dust Toxicity [0.03%]
硅醇和氧化应激在决定人造石粉尘毒性中的联合作用
Cristina Pavan,Marianna Fimiani,Stefania Cananà et al.
Cristina Pavan et al.
Engineered stone (ES) silicosis is emerging as a global occupational health crisis, caused by exposure to respirable particles generated during the processing of ES composite materials. ES composites comprise crystalline silica (predominant...
Unusual Magnetic Order in Eu11- x Hg54+ x [0.03%]
Eu_{1-mathrm{{1}}mathrm{x} }rm {Hg_{5_{{4}mathrm{{+mathrm{x}}}}}} 的非常规磁有序状态
Rachel Nixon,Nazar Zaremba,Samuel A Adegboyega et al.
Rachel Nixon et al.
In solid-state compounds, the valence of europium can sometimes be mixed, which is especially favored in structures with several positions for the europium atoms. In this work, we study the Eu-based intermetallic noncentrosymmetric system E...
Masoud Sadeghi
Masoud Sadeghi
Silver catalysis has emerged as a versatile tool for C-(sp3)-H bond functionalization, offering unique opportunities to transform simple hydrocarbons into valuable products. Both activated and unactivated C-(sp3)-H bonds have been investiga...
Substituent Effects Govern the Efficiency of Isoxazole Photoisomerization to Carbonyl‑2 H‑Azirines [0.03%]
基团效应决定异噁唑光异构化为羰基-2H氮杂环丙烷的效率
Kyra E Jackson,Isabelle Szeto,Leah M Seebald et al.
Kyra E Jackson et al.
The photoisomerization of isoxazoles is an atom-economical route to carbonyl-2H-azirines, which are valuable in both synthetic and biological applications. However, isolation of the carbonyl-2H-azirine is challenged by reverse photoisomeriz...
Fluorinated Solvents for Chemoselective Oxidations: A Strategy toward Synthetic Ideality in Natural Product Synthesis [0.03%]
用于化学选择性氧化的氟化溶剂：天然产物合成中的理想合成策略
Victor C S Santana,Lucas D P Gonçalves,Yasmin N Salmazo et al.
Victor C S Santana et al.
Late-stage catalytic oxidations of complex natural products have been shown to exhibit dramatically improved chemoselectivity through the crucial use of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), even in the presence of oxidatively sensitive...