Tunable Skeletal Editing of Benzothiazole and Benzisothiazole Via Carbene Transfer Reactions [0.03%]
通过卡宾转移反应调控苯并噻唑和苯并异噻唑的骨架编辑
Bao-Gui Cai,Xinyu Tan,Ningjie Xu et al.
Bao-Gui Cai et al.
Understanding how carbene reactivity is modulated by both the heteroarene scaffold and activation mode is critical for advancing selective functionalization strategies. Herein, we report a comparative study revealing the divergent reactivit...
Jingjing Xiong,Guanwu Lian,Kangshu Li et al.
Jingjing Xiong et al.
The chemical industry is electrifying toward a net-zero emission future. Unfortunately, the catalyst manufacturing process remains almost untouched in the transition to electrification due to challenges in size controllability and powder ha...
Machine Learned Fock Matrix [0.03%]
机器学习福克矩阵
Hongcai Liu,Shuai Guan,Zhuofan Wang et al.
Hongcai Liu et al.
This work introduces a novel machine learning integral-based self-consistent field method, called miSCF, designed for the efficient prediction of molecular electronic structures. By incorporating detailed information from the atomic informa...
Chunhai Fan,Hongzhou Gu
Chunhai Fan
Editorial
JACS Au. 2025 Nov 24;5(11):5236. DOI:10.1021/jacsau.5c01467 2025
RNA-Mediated Inhibition Mechanism of Liquid-Liquid Phase Separation and Subsequent Aggregation Revealed by Raman Microscopy [0.03%]
拉曼显微镜揭示的RNA介导的液-液相分离及后续聚集抑制机制
Taisei Ogura,Uchu Matsuura,Masato Machida et al.
Taisei Ogura et al.
Liquid-liquid phase separation (LLPS) is a phenomenon where homogeneous solutions of biomacromolecules separate into two liquid phases and generate liquid droplets enriched in specific biomolecules. LLPS of neurodegeneration-related protein...
Spatially Resolved Ion Sensing by Voltammetric Ion Transfer Microscopy [0.03%]
基于伏安法的离子转移显微镜技术用于空间分辨离子检测
Gabriel J Mattos,Justine A Rothen,Thomas J Cherubini et al.
Gabriel J Mattos et al.
The visualization and mapping of ionic species in solution and near surfaces are important to understand chemical gradients and spatially resolved dynamic processes in various fields. Available label-free approaches are either slow or restr...
Understanding the NIR Emission of Metal Nanoclusters Through a Ligand-Shell-Kernel Triad Picture [0.03%]
通过配体-壳层-核模型理解金属纳米团簇的近红外发光性质
Rui Zhao,Linlin Zeng,Fangming Zhao et al.
Rui Zhao et al.
Near-infrared (NIR)-emitting noble metal nanoclusters have received significant research interest due to their low toxicity and feasible tunability, yet their practical applications remain constrained because of low photoluminescence quantu...
1,3-Dideazaguanosine in Atomic Mutagenesis Provides Unprecedented Insight Into Hydrogen Bonding and Stacking Interactions in Folded RNA [0.03%]
1,3-二氮杂鸟苷在原子诱变中提供了关于折叠RNA中氢键和堆积相互作用的前所未有的见解
Marco Oberlechner,Ronald Micura
Marco Oberlechner
The central goal of RNA atomic mutagenesis is to evaluate the presumed contacts between individual atoms and their interaction partners with regard to function. This is made possible, for instance, by deaza-modified nucleobases, which are i...
A Water-Based and Continuous-Flow-Usable Cascade: Sustainable Synthesis of Tetrazolo-Fused Heterocycles [0.03%]
一种水相连续流可用的串联反应体系：并四唑稠合杂环化合物的合成
Yaxi Wang,Suxian Fu,Deshu Kong et al.
Yaxi Wang et al.
The innovation of energetic materials is frequently hampered by economic inefficiency and safety concerns. Emerging cascade reactions could overcome existing bottlenecks and accelerate next-generation energetic materials with enhanced scala...
Multiscale Simulation of Primary Charge Separation Mechanisms in an LH1-RC Complex [0.03%]
LH1-RC复合体初级电荷分离机制的多尺度模拟研究
Sayan Maity,Ulrich Kleinekathöfer
Sayan Maity
The light-harvesting complex II (LH2) of purple bacteria captures solar energy using bacteriochlorophyll (BChl) pigments. This energy is then transferred to the LH1 complex and subsequently to the embedded reaction center (RC). The initial ...