Disrupted neurogenesis, gliogenesis, and ependymogenesis in the Ccdc85c knockout rat for hydrocephalus model [0.03%]
用于脑积水模型的Ccdc85c基因敲除大鼠神经发生、少突胶质细胞发生和室管膜发生的紊乱
Md Mehedi Hasan,Shizuka Konishi,Miyuu Tanaka et al.
Md Mehedi Hasan et al.
Coil-coiled domain containing 85c (Ccdc85c) is a causative gene for congenital hydrocephalus and subcortical heterotopia with frequent brain hemorrhage. We established Ccdc85c knockout (KO) rats and investigated the roles of CCDC85C and int...
Cell starvation regulates ceramide-induced autophagy in mouse preimplantation embryo development [0.03%]
细胞饥饿调节鞘氨醇诱导的早期着床前胚胎自噬作用
Seung-Eun Lee,Eun-Seo Lim,Jae-Wook Yoon et al.
Seung-Eun Lee et al.
Ceramide induces autophagy upon starvation via downregulation of nutrient transporters. To elucidate the mechanism by which starvation regulates autophagy in mouse embryos, the present study investigated nutrient transporter expression and ...
Jun Zhou,Michael Boutros
Jun Zhou
Tissues such as the intestine harbor stem cells that have remarkable functional plasticity in response to a dynamic environment. To adapt to the environment, stem cells constantly receive information from their surrounding microenvironment ...
Peroxiredoxin 5 overexpression decreases oxidative stress and dopaminergic cell death mediated by paraquat [0.03%]
过表达过氧化氢酶素5可降低百草枯导致的氧化压力和多巴胺神经元死亡
Ana Patricia Duarte-Jurado,Maria de Jesus Loera-Arias,Odila Saucedo-Cardenas et al.
Ana Patricia Duarte-Jurado et al.
Peroxiredoxins (Prdxs) are thiol-dependent enzymes that scavenge peroxides. Previously, we found that Prdxs were hyperoxidized in a Parkinson's disease model induced by paraquat (PQ), which led to their inactivation, perpetuating reactive o...
Human pluripotent stem cell-based models of heart development and disease [0.03%]
基于人类多能干细胞的心脏发育和疾病模型
Gabriel Velichkova,Gergana Dobreva
Gabriel Velichkova
The heart is a complex organ composed of distinct cell types, such as cardiomyocytes, cardiac fibroblasts, endothelial cells, smooth muscle cells, neuronal cells and immune cells. All these cell types contribute to the structural, electrica...
Christian Wenzl,Jan U Lohmann
Christian Wenzl
Plant growth is driven by apical meristems at the shoot and root growth points, which comprise continuously active stem cell populations. While many of the key factors involved in homeostasis of the shoot apical meristem (SAM) have been ext...
Diana-Patricia Danciu,Jooa Hooli,Ana Martin-Villalba et al.
Diana-Patricia Danciu et al.
Adult stem cells are described as a discrete population of cells that stand at the top of a hierarchy of progressively differentiating cells. Through their unique ability to self-renew and differentiate, they regulate the number of end-diff...
Unravelling the link between embryogenesis and adult stem cell potential in the ciliary marginal zone: A comparative study between mammals and teleost fish [0.03%]
揭示哺乳动物和硬骨鱼视网膜睫状边缘区干细胞潜能与胚胎发育的联系：一种比较研究方法
Natalia Sokolova,Lucie Zilova,Joachim Wittbrodt
Natalia Sokolova
The discovery and study of adult stem cells have revolutionized regenerative medicine by offering new opportunities for treating various medical conditions. Anamniote stem cells, which retain their full proliferative capacity and full diffe...
Single-cell RNA sequencing of mouse lower respiratory tract epithelial cells: A meta-analysis [0.03%]
小鼠下呼吸道上皮细胞单细胞RNA测序的元分析
Leila R Martins,Hanno Glimm,Claudia Scholl
Leila R Martins
The respiratory system is a vital component of our body, essential for both oxygen uptake and immune defense. Knowledge of cellular composition and function in different parts of the respiratory tract provides the basis for a better underst...
Meta-Analysis
Cells & development. 2023 Jun:174:203847. DOI:10.1016/j.cdev.2023.203847 2023
Thomas W Holstein
Thomas W Holstein
Cnidarians are >600 million years old and are considered the sister group of Bilateria based on numerous molecular phylogenetic studies. Apart from Hydra, the genomes of all major clades of Cnidaria have been uncovered (e.g. Aurelia, Clytia...