From initiation to maturation: Mesenchymal stem cells as key facilitators in organoid development [0.03%]
从启动到成熟：间充质干细胞在类器官发育中的关键作用
Shihao Yi,Juan Wen,Tianshun Wang et al.
Shihao Yi et al.
Organoids are three-dimensional cellular structures formed through the self-organization of stem cells that mimic the structure and function of in vivo organs, offering broad applications in biomedical research. Mesenchymal stem cells (MSCs...
Transient versican expression is required for β1-integrin accumulation during podocyte layer morphogenesis in amphibian developing kidney [0.03%]
蛙类发育肾脏过程中足细胞层形态发生期间β1-整联蛋白积累所需的瞬时血管素表达
Isabelle Buisson,Jean-François Riou,Muriel Umbhauer et al.
Isabelle Buisson et al.
The functional organization of the vertebrate nephron is remarkably conserved, yet the morphogenetic processes underlying nephrogenesis vary across species and kidney types. The Xenopus larval kidney, the pronephros, is a non-integrated nep...
A novel role of Mef2a in mitochondrial homeostasis and muscle regeneration during sarcopenia [0.03%]
Mef2a在肌少症肌肉再生中维持线粒体稳态的新作用
Xin Tao,Suhong Zhang,Yue Li et al.
Xin Tao et al.
Sarcopenia, characterized by an age-related decline in skeletal muscle mass and function, is closely associated with mitochondrial dysfunction. This study aimed to explore the role of myocyte enhancer factor 2A (MEF2A) in alleviating sarcop...
Celebrating a century of the Spemann-mangold experiment: Self-organisation in biology [0.03%]
庆祝斯佩曼-孟加德实验一百周年：生物学中的自组织现象
Roberto Mayor
Roberto Mayor
Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes [0.03%]
头索动物活细胞排挤现象在原神经板形成过程中的机械条件研究
Santiago A Bosch-Roascio,Julio A Hernández,Flavio R Zolessi
Santiago A Bosch-Roascio
During primary neurulation in amniote embryos, the neural plate gives rise to the neural tube in a process requiring the coordination of forces at different scales throughout a geometrically complex tissue. The ways in which this process fa...
Sialoglycoproteins and sialyltransferases: Key regulators of blastocyst formation [0.03%]
糖蛋白和唾液酸转移酶：调控桑椹胚形成的關鍵因素
Pélagie Douchez,Ingrid Fliniaux,Yoshiko Takeda-Uchimura et al.
Pélagie Douchez et al.
Following fertilization, there is an initial period of rapid cell division that leads to the formation of a multicellular structure known as the blastula, or blastocyst. Within this structure, sialic acids play a key role in influencing cel...
Wnt and BMP signaling pathways pattern the anterior neuroectoderm of the indirect-developing hemichordate Ptychodera flava [0.03%]
Wnt和BMP信号通路塑造间接发育环节足动物Ptychodera flava的前神经外胚层图案
Yann Le Petillon,Tzu-Pei Fan,Yi-Chih Chen et al.
Yann Le Petillon et al.
The chordate gastrula organizer establishes Wnt and BMP signaling gradients that are essential for generating the chordate body plan. In non-chordate deuterostomes, including echinoderms and hemichordates, these two signals also contribute ...
LSM14A, an LSM family protein, is dispensable for spermatogenesis and male fertility in mice [0.03%]
LSM家族成员蛋白LSM14A在小鼠雄性生殖力中可有可无
Xu Fan,Ling Yang,Xiao Wang et al.
Xu Fan et al.
The LSM (Like-Smith) family comprises RNA-binding proteins (RBPs) that are key regulators of RNA metabolism. LSM14A, a member of this family (designated Lsm14a in mice), participates in RNA processing within cytoplasmic processing bodies (P...
Extracellular vesicles: A complex array of particles involved in cell-to-cell communication for tissue homeostasis [0.03%]
细胞外囊泡：一种参与组织稳态细胞间通讯的颗粒数组
Natayme Rocha Tartaglia,Lorena Martin-Jaular,Alain Joliot et al.
Natayme Rocha Tartaglia et al.
Communication between cells is an inescapable feature of every multicellular organism, from the coordination of development during embryogenesis to the maintenance of homeostasis throughout adulthood. Extracellular vesicles (EVs) are new an...
Tissue-resident macrophages contribute to ear hole regeneration of early postnatal mice [0.03%]
组织驻留巨噬细胞参与新生小鼠耳孔再生
René Fernando Abarca-Buis,Blanca Alicia Barredo-Prieto,David Garciadiego-Cázares et al.
René Fernando Abarca-Buis et al.
Healing of ear holes made in early postnatal mice represents an accessible model for the study of the regeneration of multiple tissues in mammals. This regenerative process involves three phases: wound healing, blastema formation, and re-di...