Peroxiredoxin 5 overexpression decreases oxidative stress and dopaminergic cell death mediated by paraquat
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Peroxiredoxins (Prdxs) are thiol-dependent enzymes that scavenge peroxides. Previously, we found that Prdxs were hyperoxidized in a Parkinson's disease model induced by paraquat (PQ), which led to their inactivation, perpetuating reactive oxygen species (ROS) ... ...