Neuroprotective properties of Linzia gerberiformis aqueous leaves extract against aluminium chloride (AlCl3) -induced cognitive impairment: Involvement of cholinergic, GABAergic, and antioxidant mechanisms [0.03%]
Linzia gerberiformis叶提取物的神经保护特性对抗铝氯化物(AlCl3)引起的认知障碍:胆碱能,GABA能和抗氧化机制的参与
Jospin Chirac Noubouwo,Gwladys Temkou Ngoupaye,Steve Brunel Kenfack Ngoufack et al.
Jospin Chirac Noubouwo et al.
Neurodegenerative diseases, such as Alzheimer's disease (AD), are characterized by oxidative imbalance, leading to memory deficits and cognitive impairments. Aluminium chloride (AlCl3), a neurotoxin found in certain foods and medications, d...
Exploring the mechanism of analogy and explicit instructions on self-efficacy, performance, and learning of golf putting task: Analysis of mental representation [0.03%]
类比机制及自我效能明确指令对高尔夫推球任务学习中心理表征的分析
Saeed Nazari Kakvandi,Morteza Homayounnia Firouzjah,Wing-Kai Lam et al.
Saeed Nazari Kakvandi et al.
Previous research has shown the structure of mental representation of learners modifies and develops during motor learning. However, few studies have examined the development of mental representation during various organization of practice....
Therapeutic effectiveness of conditioned medium derived from adipose tissue mesenchymal stem cells and dehydroepiandrosterone in a rat model of spinal cord injury [0.03%]
来自脊髓损伤大鼠模型的脂肪组织间充质干细胞和脱氢表雄酮衍生的条件培养基的治疗效果
Farrokh Modarresi,Gholam Reza Kaka,Mehdi Raei et al.
Farrokh Modarresi et al.
Background and objective: Spinal cord injury (SCI) is a severe neurological disorder that leads to significant complications, including loss of bladder/bowel control and increased infection risk. The current standard trea...
Frankincense improves motor symptoms and attenuates the progression of Paraquat (PQ)-induced Parkinson's disease in mice by attenuating oxidative stress, inflammation, and apoptotic cell death and improving nerve growth factor gene expression [0.03%]
乳香改善甲草胺(PQ)诱导的小鼠帕金森病患者的运动症状并减缓病情进展通过减轻氧化应激,炎症和凋亡细胞死亡以及改善神经生长因子基因表达
Sakine Shalikar,Mohammad Amin Mashayekhpour,Soheila Ebrahimi Vosta-Kalaee et al.
Sakine Shalikar et al.
The purpose of the present investigation is to examine the neuroprotective impact of frankincense at different concentrations (10, 20, and 50 mg/kg/day) and discover its potential mechanisms associated with oxidative stress and apoptosis. T...
Shared genetic architecture of psychiatric disorders and ocular diseases: Evidence from genome-wide analyses [0.03%]
精神疾病和眼科疾病的共享遗传结构:来自全基因组分析的证据
Zhao-Yang Zhang,Huan-Xi Liu,Xiao-Jia Ma et al.
Zhao-Yang Zhang et al.
Objective: Psychiatric disorders are frequently comorbid with ocular diseases, yet the shared genetic basis and potential causal links remain unclear. This study aimed to systematically investigate the shared genetic arch...
Elevated serum trimethylamine N-oxide (TMAO) and trimethyllysine in patients with amyotrophic lateral sclerosis (ALS): An exploratory case-control study [0.03%]
肌萎缩侧索硬化患者中升高的血清三甲胺N-氧化物(TMAO)和三甲基赖氨酸:一项探索性病例对照研究
Salvatore Sotgia,Angelo Zinellu,Stefano Zoroddu et al.
Salvatore Sotgia et al.
Trimethylamine N-oxide (TMAO) is a gut microbiota-derived metabolite implicated in protein homeostasis, inflammation, and chronic disease, but its relevance in amyotrophic lateral sclerosis (ALS) remains poorly characterized. In this explor...
Association between dietary magnesium intake and epilepsy: The mediating role of composite dietary antioxidant index based on a cross-sectional study [0.03%]
基于横断面研究的饮食镁摄入与癫痫的关系及总膳食抗氧化指数的中介作用分析
Yali Lai,Yi Zhou,Le Yang et al.
Yali Lai et al.
Background: Epilepsy affects 1.2 % of the US population, with one-third of cases being drug-resistant. Magnesium modulates neuronal excitability, and dietary insufficiency may elevate seizure risk. Systemic inflammation, ...
Lewen Zhao,Xingyuan Liu,De-Hua Wu et al.
Lewen Zhao et al.
The functional architecture of the primary visual cortex (V1)-manifesting as orientation selectivity maps (OS maps) in higher mammals and modular tuning clusters in rodents-provides a window into the rules governing cortical circuit organiz...
Physical exercise as a non-pharmacological strategy to enhance glymphatic function [0.03%]
运动作为一种非药物策略增强glymphatic功能
Arman Ghayourvahdat,Hannaneh Azimizonuzi,Moslem Ahmed
Arman Ghayourvahdat
The glymphatic system plays a critical role in clearing metabolic waste and neurotoxic proteins from the brain, and its dysfunction is implicated in neurodegenerative diseases such as Alzheimer's disease (AD). Emerging evidence indicates th...
Prefrontal TDCS does not improve working memory performance in individuals with chronic alcohol and tobacco use [0.03%]
经前额叶TDCS不能改善慢性酒精和烟草使用者的工作记忆性能
Franziska Göttgens,Ute Habel,Paul Wallheinke et al.
Franziska Göttgens et al.
Working memory (WM) deficits are common in psychiatric disorders that are associated with decreased prefrontal cortex activity. As WM is essential for cognitive functions, deficits interfere with daily life and treatment. The lateralization...