Hesperidin mitigates cognitive and anxiety-like deficits by enhancing hippocampal antioxidant defenses, reducing neuroinflammation, and preventing neuronal apoptosis in a third-trimester-equivalent rat model of developmental ethanol neurotoxicity [0.03%]
苦橙素通过增强海马抗氧化防御、减少神经炎症和防止发育性酒精神经毒性第三 trimester 相当大鼠模型中的神经元凋亡来缓解认知和类似焦虑的缺陷
Zhaleh Jamali,Fahimeh Mohseni,Ahmad Salimi et al.
Zhaleh Jamali et al.
Ethanol exposure during brain development has been associated with hippocampal oxidative stress, neuroinflammation, and apoptosis, resulting in lasting cognitive and emotional deficits characteristic of fetal alcohol spectrum disorders (FAS...
Metabolic profile association with white matter hyperintensity in patients with mild cognitive impairment [0.03%]
轻度认知障碍患者白质高信号与代谢谱特征的相关性研究
Armin Ariaei,Raziyeh Zamiri,Amirabbas Ghasemi et al.
Armin Ariaei et al.
Brain vasculopathy, including cerebral white matter hyperintensity (WMH), is highly associated with mild cognitive impairment (MCI) and Alzheimer's disease (AD) pathology. Metabolite levels provide clues to illuminate the mechanism of WMH i...
Establishment of a novel rat model of chronic subdural hematoma: Recapitulating human pathological features through triple-component induction [0.03%]
建立新型慢性硬膜下血肿大鼠模型：通过三因素诱导再现病理特征
Qiuyu Lu,Renkun Zhang,Yuhao Tan et al.
Qiuyu Lu et al.
Objectives: This study aimed to develop a novel rat model of Chronic subdural hematoma (CSDH) that better recapitulates human pathophysiological mechanisms, enhancing clinical relevance for translational research. ...
Exploring the mechanisms of biofield therapy through joint electrophysiological recordings in humans and mice [0.03%]
通过人类和小鼠的联合电生理记录探索生物场疗法的作用机制
Arnaud Delorme,Andrew Cusimano,Megan Tran et al.
Arnaud Delorme et al.
In this case study, a self-described biofield therapy (BT) therapist and a sham therapist participated in multiple (n = 24) treatment and control (non-treatment) sessions under double-blind conditions. During the treatment phases, BT and sh...
Unraveling seizure interruptions: Excitability dynamics in spike-wave activity [0.03%]
解开癫痫发作中断之谜：尖峰波活动中的兴奋性动力学
Gilles van Luijtelaar,Bob de Ruijter
Gilles van Luijtelaar
Neuronal activity during a spike-wave complex (SWC) consists of highly synchronized firing of neuronal populations followed by a period of neuronal silence. It may manifest as an interictal spike or repetitive. Cortical excitability during ...
The functional role of opioidergic system within the ventral tegmental area and the dentate gyrus of hippocampus in modulation of the persistent inflammatory pain in the rats [0.03%]
伏隔核和海马齿状回阿片系统在大鼠持续性炎症痛调节中的功能作用
Mohammad Saghafi,Ronak Azizbeigi,Abbas Haghparast
Mohammad Saghafi
The ventral tegmental area (VTA) and hippocampus are implicated in various brain functions, including pain modulation. However, the precise involvement of their opioidergic system in this process has not yet been fully elucidated. The curre...
Cortical transcriptomic dysregulation in Autism spectrum disorder: A conceptual synthesis [0.03%]
自闭症谱系障碍中皮层转录调控异常的概念整合
Ruslan Kurmashev
Ruslan Kurmashev
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition in which human post-mortem cortical transcriptomic studies have identified recurrent but context-sensitive molecular abnormalities. This narrative review synthes...
Anticipatory slow potentials before auditory feedback show posterior predominance but limited condition effects in speech-in-noise [0.03%]
语音噪声环境中听觉反馈诱发的预期性负波主要位于后部且不同类型噪声中的变化有限
Kazuhiro Okamoto,Kengo Hoyano,Tomomi Nomura et al.
Kazuhiro Okamoto et al.
It remains unclear whether noisy listening reliably modulates anticipatory EEG activity before feedback and whether such activity explains interindividual differences in speech-in-noise performance. We examined these questions in an indepen...
Antiepileptic and antiepileptogenic effects of Lagenaria siceraria aqueous extract (Curcubitaceae) in PTZ-induced kindling in rats [0.03%]
Lagenaria siceraria 水提物对PTZ诱导的大鼠癫癎发作的抗癫癎和抗癫癎生成作用研究
King-Ghislain Kenne Gnoupa,Gwladys Temkou Ngoupaye,Aurelien Fossueh Foutsop et al.
King-Ghislain Kenne Gnoupa et al.
Lagenaria siceraria (Curcubitaceae) is a plant traditionally used in Cameroon to treat epilepsy and other central nervous system disorders. The present study investigated the antiepileptogenic and antiepileptic effects of Lagenaria sicerari...
Context-dependent modulation of LTP and BDNF/TrkB signaling in the dentate gyrus following combined progressive aerobic and rotarod training in male wistar rats [0.03%]
有氧运动和旋转杆训练对Wistar大鼠海马齿状回长时程增强和BDNF/TrkB信号转导的调节作用
Mojtaba Sadeghi,Alireza Komaki,Farzad Nazem
Mojtaba Sadeghi
Background: Aerobic exercise and motor skill training independently influence hippocampal plasticity; however, their interaction when motor learning occurs under conditions of exercise-induced exhaustion remains incomplet...