Navigating Opportunities and Challenges in Large-Scale Longitudinal Electroencephalography Studies [0.03%]
大规模纵向脑电研究的机会与挑战
Ingmar H A Franken,Olga D Boer,Hanan El Marroun
Ingmar H A Franken
A Novel Polygenic Risk Score Indexing Somatostatin-Expressing Inhibitory Neurons Predicts Somatostatin-Expressing Cell Proportions and Severity of Symptoms in Late-Life Depression [0.03%]
一种新型多基因风险评分可索引生长抑素表达的抑制性神经元，预测晚发抑郁症中生长抑素细胞比例及症状严重程度
Fernanda C Dos Santos,Xiaolin Zhou,Kevan P Clifford et al.
Fernanda C Dos Santos et al.
Background: Postmortem studies suggest that somatostatin-expressing (SST+) interneurons are selectively vulnerable in aging and depression. We developed a novel polygenic risk score (PRS) as an in vivo index of interindiv...
Ketamine Improves Anhedonic Phenotypes Across Species: Translational Evidence From the Probabilistic Reward Task [0.03%]
氯胺酮改善跨物种快感缺失表型：来自概率奖励任务的实证证据
Mario Bogdanov,Jason N Scott Jr,Shiba M Esfand et al.
Mario Bogdanov et al.
Background: Ketamine is increasingly used as a therapeutic option for treatment-resistant depression (TRD) due to its rapid antidepressant properties; however, the mechanisms underlying these effects remain elusive. Precl...
[This corrects the article DOI: 10.1016/j.bpsgos.2025.100578.]. © 2025 The Authors.
Has Deep Brain Stimulation Shown Its Full Potential in Treatment-Resistant Depression? A Scoping Review [0.03%]
深脑刺激在难治性抑郁治疗中潜力几何？系统综述来揭秘
Liene Puke,Joelle Rosselet Amoussou,Armin von Gunten et al.
Liene Puke et al.
Major depressive disorder is increasingly conceptualized as a networkopathy involving dysfunction across brain networks rather than isolated regions. This perspective has supported the use of deep brain stimulation (DBS) in treatment-resist...
Phenome-Wide Associations of Polygenic Scores for Schizophrenia and Major Depression in 100,000 Chinese Adults [0.03%]
基于中国成年人的性状全尺度关联分析精神分裂症和抑郁症多基因风险评分的影响
Baihan Wang,Sam Morris,Hannah Fry et al.
Baihan Wang et al.
Background: China faces significant mental health challenges, with unique associations between mental disorders and other traits observed in its population. ...
The Occipital-Fronto-Limbic Circuit of Body Dysmorphic Disorder: A Systematic Review and Meta-Analysis of Neuroimaging Studies [0.03%]
身体变形障碍的 occipito-fronto-limbic 环路：神经影像学研究的系统性回顾和元分析
Yihui Cheng,Emalee Burrows,Ludvic Zrinzo et al.
Yihui Cheng et al.
Background: Body dysmorphic disorder (BDD) is a severe psychiatric disorder characterized by excessive preoccupation with perceived flaws in appearance. In this review, we aim to synthesize the latest findings on the neur...
Lower Gyrification of the Ventromedial Prefrontal Cortex in Posttraumatic Stress Disorder: An ENIGMA-PTSD Study [0.03%]
创伤后应激障碍患者腹内侧前额叶皮层折叠度降低：ENIGMA- PTSD研究结果
Ahmed Hussain,C Lexi Baird,Ashley A Huggins et al.
Ahmed Hussain et al.
Background: Cortical gyrification involves the formation of folds in the cerebral cortex, coinciding with key neurodevelopmental processes. Its strong correlation with increased cortical surface area and decreased cortica...