Functional Connectivity in the Social Perception Pathway at Birth Is Linked to Attention to Faces at Four Months [0.03%]
出生时的社会感知通路的功能连接与四个月时的面部注意力有关
Katarzyna Chawarska,Angelina Vernetti,Huili Sun et al.
Katarzyna Chawarska et al.
Background: The right-lateralized social perception pathway, including the superior temporal sulcus, supports processing of dynamic, multimodal facial cues, while the right-lateralized ventral pathway, including the fusif...
Differences in High-Frequency Connectivity Among Large-Scale Functional Networks Linked to Major Depressive Disorder and Treatment-Resistant Depression [0.03%]
与重度抑郁症和难治性抑郁相关的大型功能网络之间的高频连接差异
Ty Lees,Sarah E Woronko,Mohan Li et al.
Ty Lees et al.
Background: Major depressive disorder (MDD) and treatment-resistant depression (TRD) have each been characterized by altered neural connectivity largely associated with the triple model of the default mode (DMN), frontopa...
Longitudinal Relationship of Early Postnatal Testosterone and Harsh Parenting at 1-3 Months of Age to Physical Aggression at 12 Months of Age in Boys and Girls [0.03%]
婴儿期睾酮水平和严厉养育对幼儿攻击性行为的预测作用：一项纵向研究
Karson T F Kung,Rachel L C Li,Eddy C H Tam et al.
Karson T F Kung et al.
Background: It has been postulated that the early postnatal period, 1 to 3 months of age, is a critical period when early androgen exposure exerts long-lasting influences on aspects of behavioral development that show sex...
Exploration of a DDX3X Gene Supplementation Therapy Including Expanded Characterization and Novel Findings of Sleep Disturbances in Ddx3x Haploinsufficient Mice [0.03%]
DDX3X基因补充治疗的探索及其单倍体不足小鼠睡眠障碍的扩展特征和新发现
Andrea Boitnott,Anjala Jiji,Erik J Plautz et al.
Andrea Boitnott et al.
Background: DDX3X syndrome is a neurodevelopmental disorder caused by mutations in the DDX3X gene. It is one of many rare diseases for which there is no adequate treatment, but it has characteristics that make it potentia...
Effects of Shared and Nonshared Schizophrenia and Bipolar Disorder Alleles on Cognition and Educational Attainment in the UK Biobank [0.03%]
英国生物样本库中精神分裂症和双相情感障碍共享与非共享易感基因对认知功能和教育水平的影响
Alexander L Richards,Eilidh Fenner,Nicholas E Clifton et al.
Alexander L Richards et al.
Background: Cognitive impairment is typically more severe in schizophrenia (SZ) than bipolar disorder (BD). We explored the underlying genetics and biology of this difference and its relationship to educational attainment...
Increasing SOX10 Expression Overcomes Schizophrenia-Associated Early Oligodendrocyte Growth Deficits In Vitro [0.03%]
SOX10表达增强可克服 schizophrenia引起的早期少突胶质细胞增殖缺陷
Donna L McPhie,Juan Antonio García-León,Catherine M Verfaillie et al.
Donna L McPhie et al.
Background: Individuals with schizophrenia (SZ) tend to have lower than average brain myelin content. Gene-set analyses suggest that aberrant oligodendrocyte (OL) development is an underlying cause of this abnormality. Pr...
The Clinical Relevance of Immunopsychiatric Treatment: Lessons From a Transdiagnostic Case Series on Young People [0.03%]
免疫精神病学治疗的临床意义：关于年轻人跨诊断病例系列的经验教训
Luca Sforzini,Carmine M Pariante
Luca Sforzini
Transcriptomic Architecture of Weak Versus Strong Contextual Fear Extinction Learning Uncovers Extinction-Suppressive Role of TIA1 [0.03%]
弱上下文恐惧消除学习与强上下文恐惧消除学习的转录组架构差异揭示TIA1对消除的抑制作用
Maria I Bonilla,Hae-Lim Lee,Stephen Foster et al.
Maria I Bonilla et al.
Background: Extinction, the capacity for an individual to inhibit or diminish fear memories, is a critical aspect of fear processing. In humans, weak extinction learning is often observed in anxiety and fear-related disor...
Decreased Mitochondrial DNA Integrity and Elevated Inflammatory Markers in Late-Life Depression: A Longitudinal Study [0.03%]
老年人抑郁症中线粒体DNA完整性和炎症标志物的纵向研究
Ana Paula Mendes-Silva,Perla El-Ahmad,Ana Paula Costa et al.
Ana Paula Mendes-Silva et al.
Background: Late-life depression (LLD) is a prevalent and severe mental disorder. The biological mechanisms underlying LLD are not fully understood, but increasing evidence suggests that mitochondria play a significant ro...