A Novel Polygenic Risk Score Indexing Somatostatin-Expressing Inhibitory Neurons Predicts Somatostatin-Expressing Cell Proportions and Severity of Symptoms in Late-Life Depression
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Background: Postmortem studies suggest that somatostatin-expressing (SST+) interneurons are selectively vulnerable in aging and depression. We developed a novel polygenic risk score (PRS) as an in vivo index of interindividual va... ...
