Electroconvulsive Treatment for Depression Alters Mitochondrial Serum Metabolites [0.03%]
电休克治疗可改变抑郁症患者外周血线粒体代谢物水平
Erik Pålsson,Robert Sigström,Alireza Salehi et al.
Erik Pålsson et al.
Background: Electroconvulsive therapy (ECT) is the most effective treatment for severe and treatment-resistant depression, but its biological mechanisms remain poorly understood. Given the pivotal role of mitochondria in ...
Adolescent Hormonal Contraceptive Use in the Context of Brain Development and Depression Risk: A Review and Considerations for Future Research [0.03%]
青春期激素避孕的脑发育和抑郁风险研究综述及未来研究展望
Niamh MacSweeney,Taleah Dumoulin,Eira R Aksnes et al.
Niamh MacSweeney et al.
Hormonal contraceptives (HCs) contain synthetic gonadal hormones that act on receptors widely distributed throughout the brain, thereby altering the body's endogenous hormonal milieu in ways that may influence brain and behavior. Although H...
Cannabis and Psychosis: Genomic Methods Shed Light on Pathophysiological Processes [0.03%]
大麻和精神病：基因组方法揭示发病生理过程
Jack F G Underwood,Jeremy Hall
Jack F G Underwood
Epigenetic Aging and Cognitive Performance in General and Psychiatric Populations: A Systematic Review and Narrative Synthesis [0.03%]
表观遗传衰老与认知表现：一般人群和精神病患者中的系统性综述及叙述综合
Natan Yusupov,Julia Fietz,Vera N Karlbauer et al.
Natan Yusupov et al.
Epigenetic aging and age-related cognitive decline both show substantial variability across individuals. While a potential link between the two is increasingly being studied in both general and psychiatric populations, a systematic review h...
Neuroimaging-Based Subgroups in Schizophrenia: A Critical Appraisal of Clustering Studies [0.03%]
基于神经影像的精神分裂症亚组：聚类研究的批判性评估
Yuetong Yu,Ruiyang Ge,Sophia Frangou
Yuetong Yu
Efforts to define biologically grounded subtypes of schizophrenia have increasingly leveraged neuroimaging data and clustering algorithms. Such approaches aim to capture patient-level heterogeneity with potential clinical and mechanistic re...
Reimagining the Biopsychosocial Model: Transdiagnostic Factors to Precision Psychiatry [0.03%]
重塑生物心理社会模型：从跨诊断因素到精准精神病学
Maja Nikolic,Charlotte B Caswell,Nicole Palacio Prada et al.
Maja Nikolic et al.
Background: We recently reported evidence that a biopsychosocial model predicts lifetime histories of commonly comorbid early-onset psychiatric disorders. This transdiagnostic model was produced when incorporating either ...
Anhedonia and Anxious Arousal Are Associated With Distinct Expectations About the Statistics of a Volatile Environment [0.03%]
无乐症和焦虑唤醒与对多变环境统计特征的不同预期有关
Jessica M Duda,Tyrone D Cannon,Samuel Paskewitz et al.
Jessica M Duda et al.
Background: The brain is believed to construct a generative model of the environment, updated via differences between predictions and incoming sensory evidence (i.e., prediction errors). Uncertainty can arise at multiple ...
A Distinct Subpopulation of Extended Amygdala Neurons Drives Food Intake [0.03%]
下丘脑室旁核路易克斯小体通路在应激促进暴食中的作用
Isaac F Kandil,Ethan T Rogers,Allison R Morningstar et al.
Isaac F Kandil et al.
Background: Neurons in the oval subnucleus of the bed nucleus of the stria terminalis (ovBNST) integrate stress and reward signals to regulate motivated behaviors, including food consumption. However, the contribution of ...
Understanding Sex and Gender Effects on Autism Spectrum Disorder and Obsessive-Compulsive Disorder: Clinical Presentation and Risk Factors [0.03%]
理解性别对自闭症谱系障碍和强迫症的临床表现和风险因素的影响
Allison Pearlman,Amelia Abell,Pia Jauhar et al.
Allison Pearlman et al.
Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) exhibit significant sex and gender differences in prevalence, clinical presentation, and risk factors. Males are diagnosed with ASD 4 times more frequently than females,...