Masaaki Matsubara,Mayumi Ishihara,Michael Tiemeyer et al.
Masaaki Matsubara et al.
Glycosphingolipids are essential components of all eukaryotic cells and play a major role in a broad range of cellular and biological processes, including growth, cell signaling, survival, differentiation, and disease. Glycosphingolipid str...
Richard Liangchen Wang
Richard Liangchen Wang
In contemporary biology, the predominant paradigm is that life is chemistry. This means that all biological processes could be reduced to physicochemical processes. Some scientists have argued that life is chemistry plus information, but th...
Claudin-11, a hypomyelinating leukodystrophy 22 (HLD22)-responsible protein, uniquely interacts with shroom-2 to change cell phenotypes [0.03%]
Claudin-11通过与shroom-2的特异相互作用来改变细胞表型以影响脱髓鞘病变的发展
Sakurako Kobayashi,Takanori Yokoi,Takeru Omata et al.
Sakurako Kobayashi et al.
Oligodendroglial cells are a type of glial cell in the central nervous system (CNS) that wrap neuronal axons with differentiated plasma membranes known as myelin sheaths. While the physiological functions of oligodendrocytes, such as genera...
An enhanced dual detection of DMB-labeled sialic acids using high-resolution accurate mass spectrometry and fluorescence detection [0.03%]
结合高分辨质谱和荧光检测增强DMB标记唾液酸的双模式分析法
Takayuki Omoto,Nao Yamakawa,Di Wu et al.
Takayuki Omoto et al.
Sialic acids are important glycan components not only in the conformation of the structure but also in functions of many biological activities. Detection methods for sialic acid have been developed, and fluorescent labeling of sialic acids ...
Evolution and function of galectins in Xenopus laevis: Comparison with mammals and new perspectives [0.03%]
非洲爪蟾半乳糖凝集素的进化与功能及其与哺乳动物的比较和新的研究视角
Takashi Ogawa,Yasuhiro Nonaka,Hiroki Shoji et al.
Takashi Ogawa et al.
Galectins are metal-independent sugar-binding proteins that recognize galactose (the β-galactoside structure) and regulate the cross-linking of sugar chains between cells and the extracellular matrix. Their specificity for galactose is att...
Current issues of tandem mass spectrum (MS2)-based glycoproteomics and efforts to complement them [0.03%]
基于串联质谱的糖蛋白质组学当前问题及补充分析的努力
Hiroyuki Kaji
Hiroyuki Kaji
With the development of liquid chromatography/mass spectrometers that support proteomics and the associated development of analytical methods and data analysis software, the number of proteins that can be identified and quantified in a sing...
Characterization of HOL-30: a novel tandem-repeat galectin from the marine sponge Halichondria okadai [0.03%]
HOL-30的特征研究：来源于海洋海绵Okada's halichondria的新颖串联重复半乳糖凝集素
Mayuka Ohkawa,Kenichi Kamata,Sarkar M A Kawsar et al.
Mayuka Ohkawa et al.
We here report the novel primary structure of a new member in the galectin family, the β-galactoside-binding lectin HOL-30, from the marine sponge Halichondria okadai, whose full-length sequence was determined thanks to the combination bet...
Clara Dessenne,Christophe Mariller,Olivier Vidal et al.
Clara Dessenne et al.
Bacterial adhesins play a central role in host-pathogen interactions, with many specifically targeting glycans to mediate bacterial colonization, influence infection dynamics, and evade host immune responses. In this review, we focus on bac...
Frédérique Lisacek,Boris Schnider,Anne Imberty
Frédérique Lisacek
Lectins are ubiquitous proteins that interact with glycans in a variety of molecular processes and as such, also play a role in diseases, whether infectious, chronic or cancer-related. The systematic study of lectins is therefore essential,...
Development of a permethylation-based detection method for oligo/polysialic acid structures via tandem MALDI-TOF mass spectrometry [0.03%]
基于串聯MALDI-TOF質譜的寡/聚唾液酸結構的全甲基化檢測方法的建立
Kai Suzuki,Di Wu,Ken Kitajima et al.
Kai Suzuki et al.
Oligo/polysialic acid (oligo/polySia) refers to a class of linear polymers composed of Sias, found extensively at the non-reducing ends of glycans across various organisms, from bacteria to vertebrates. Different types of oligo/polySia have...