Unravelling lipid heterogeneity: Advances in single-cell lipidomics in cellular metabolism and disease [0.03%]
解开脂质异质性之谜：单细胞脂质组学在细胞代谢和疾病研究中的进展
Sutanu Sarkar,Rajgourab Ghosh
Sutanu Sarkar
Recent advancements in single-cell analysis have revolutionized our understanding of cellular heterogeneity, particularly in lipid metabolism. Single-cell lipidomics, enabled by ultra-sensitive mass spectrometry techniques such as Orbitrap ...
F-type lectins: Structural and functional aspects, and potential biomedical applications [0.03%]
F型凝集素：结构和功能及潜在的生物医学应用
Gerardo R Vasta,Mario A Bianchet
Gerardo R Vasta
Among the multiple animal lectin families recognized to date, F-type lectins (FTLs), fucose-binding lectins characterized by an FTL domain (FTLD), constitute the most recent lectin family to be identified and structurally characterized. The...
Best evidence linking the extracellular factor TGF-β to cancer-associated alternative splicing programs [0.03%]
最佳证据揭示细胞因子TGF-β与癌症相关可变剪接程序的关联
Opeoluwa Alli-Oke,Jean-Philippe Brosseau
Opeoluwa Alli-Oke
Alternative splicing is a mechanism by which several RNA transcripts can be created from one gene. Splicing factors are RNA binding proteins recognizing cis-acting sequences that positively or negatively influence the splicing decision base...
MALDI O-antigen glycotyping of Y. pseudotuberculosis using DAN/DHB/K matrix [0.03%]
使用DAN/DHB/K矩阵对Y. pseudotuberculosis进行MALDI O抗原糖型分析
Shogo Urakami,Hiroshi Hinou
Shogo Urakami
Yersinia pseudotuberculosis is a zoonotic gram-negative bacterium with a wide range of hosts. Twenty-one classifications of O-antigens of Y. pseudotuberculosis, including their glyco-subtypes, have been reported and used as epidemiological ...
Phosphorylation of the fission protein Drp1 contributes to the impact of the curcuminoid 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one on mitochondrial and cellular processes [0.03%]
分裂蛋白Drp1的磷酸化有助于类姜黄素1,7-二（4-羟基苯基）-1,4,6-庚三烯-3-酮对线粒体和细胞过程的影响
Navyamol Chakkalaparambil Dileep,Chi-Wei Chiu,Ching-Tse Wu et al.
Navyamol Chakkalaparambil Dileep et al.
Curcumin and its curcuminoid derivatives extracted from turmeric have been investigated for their potential therapeutic benefits in cancer treatment. Curcuminoids 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one and bisdemethoxycurcumin can ...
Vishakha Sherawat,Deepika Sharma
Vishakha Sherawat
Netrin-1, a secreted laminin-related protein, was first characterized for its pivotal role in guiding axonal growth during nervous system development. However, recent research has revealed its involvement in cancer progression and metastasi...
Masaaki Matsubara,Mayumi Ishihara,Michael Tiemeyer et al.
Masaaki Matsubara et al.
Glycosphingolipids are essential components of all eukaryotic cells and play a major role in a broad range of cellular and biological processes, including growth, cell signaling, survival, differentiation, and disease. Glycosphingolipid str...
Richard Liangchen Wang
Richard Liangchen Wang
In contemporary biology, the predominant paradigm is that life is chemistry. This means that all biological processes could be reduced to physicochemical processes. Some scientists have argued that life is chemistry plus information, but th...
Claudin-11, a hypomyelinating leukodystrophy 22 (HLD22)-responsible protein, uniquely interacts with shroom-2 to change cell phenotypes [0.03%]
Claudin-11通过与shroom-2的特异相互作用来改变细胞表型以影响脱髓鞘病变的发展
Sakurako Kobayashi,Takanori Yokoi,Takeru Omata et al.
Sakurako Kobayashi et al.
Oligodendroglial cells are a type of glial cell in the central nervous system (CNS) that wrap neuronal axons with differentiated plasma membranes known as myelin sheaths. While the physiological functions of oligodendrocytes, such as genera...
An enhanced dual detection of DMB-labeled sialic acids using high-resolution accurate mass spectrometry and fluorescence detection [0.03%]
结合高分辨质谱和荧光检测增强DMB标记唾液酸的双模式分析法
Takayuki Omoto,Nao Yamakawa,Di Wu et al.
Takayuki Omoto et al.
Sialic acids are important glycan components not only in the conformation of the structure but also in functions of many biological activities. Detection methods for sialic acid have been developed, and fluorescent labeling of sialic acids ...