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CaF2 nanoparticles deliver siRNA targeting STAT6 and PPAR- [Formula: see text] to depolarise tumour-associated macrophages

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Breast cancer is a leading cause of death in women, partly due to challenges posed by constituents of the tumour-microenvironment, such as tumour-associated macrophages (TAMs). Polarisation of macrophages to a pro-tumour phenotype usually involves STAT6 and PP... ...