ITGB2 is a central hub-gene associated with inflammation and early fibro-atheroma development in a swine model of atherosclerosis [0.03%]
ITGB2是猪动脉粥样硬化模型中与炎症和早期纤维斑块形成相关的中心骨架基因
Hadjer Namous,Maria Giuseppina Strillacci,Camila Urbano Braz et al.
Hadjer Namous et al.
Background and aim: The complex dynamic interplay between different biological pathways involved in atherosclerosis development has rendered the identification of specific therapeutic targets a challenging quest. We aimed...
Fetuin-A levels in association with calcific aortic valve disease: A meta-analysis [0.03%]
与主动脉瓣钙化相关的 Fetuin-A 水平：一项荟萃分析
Muhammad Omar Larik
Muhammad Omar Larik
Background and aims: Calcific aortic valve disease (CAVD) is a common valvular disease, prevalent particularly within the older age groups. The potential use of biomarkers in diagnosing and assessing the severity of CAVD,...
The LIPL study: Postprandial lipid profile, inflammation, and platelet activity in patients with chronic coronary syndrome [0.03%]
LIPL研究：慢性冠状动脉综合征患者的餐后血脂、炎症和血小板活性
Edita Pogran,Paul M Haller,Claudia Wegberger et al.
Edita Pogran et al.
Background and aims: It is suggested that the changes in atherosclerosis happen mainly under the influence of non-fasting lipids. To date, the studies in the postprandial state were primarily performed on healthy subjects...
Prediabetes is an incremental risk factor for adverse cardiac events: A nationwide analysis [0.03%]
糖尿病前期是不良心脏事件的增量危险因素：全国范围内的分析研究
Dhairya Nanavaty,Rhea Green,Ankushi Sanghvi et al.
Dhairya Nanavaty et al.
Background and aims: Prediabetes is defined as a state of impaired glucose metabolism with hemoglobin A1c (HbA1c) levels that precede those of a diabetic state. There is increasing evidence that suggests that hyperglycemi...
High-density lipoprotein cholesterol and multiple myeloma: A systematic review and meta-analysis [0.03%]
高密度脂蛋白胆固醇与多发性骨髓瘤的关联：系统评价和Meta分析
Anastasios Makris,Antonia Pagkali,Emmanouil Nikolousis et al.
Anastasios Makris et al.
Background and aims: To systematically investigate all relevant evidence on the association between high-density lipoprotein cholesterol (HDL-C) and multiple myeloma (MM). ...
Lipoprotein(a), Interleukin-6 inhibitors, and atherosclerotic cardiovascular disease: Is there an association? [0.03%]
脂蛋白(a)、白细胞介素-6抑制剂与动脉粥样硬化性心血管疾病之间的关系？
Anastasios Makris,Fotios Barkas,Petros P Sfikakis et al.
Anastasios Makris et al.
Background and aims: Lipoprotein(a) [Lp(a)] and interleuking-6 (IL-6), an inflammation biomarker, have been established as distinct targets of the residual atherosclerotic cardiovascular disease (ASCVD) risk. We aimed to ...
Menno Hoekstra,Miranda Van Eck
Menno Hoekstra
Background and aims: Non-alcoholic fatty liver disease (NAFLD), a high incidence liver pathology, is associated with a ∼1.5-fold higher cardiovascular disease risk. This phenomenon is generally attributed to the NAFLD-as...
Increased extracellular vesicles (EVs) related to T cell-mediated inflammation and vascular function in familial hypercholesterolemia [0.03%]
在家族性高胆固醇血症中T细胞介导的炎症和血管功能相关的细胞外囊泡(EVs)增多
Morten Hjuler Nielsen,Rikke Bæk,Malene Moller Jorgensen et al.
Morten Hjuler Nielsen et al.
Background and aims: OxLDL modulates innate and adaptive immunity, and extracellular vesicles (EVs) released from both non-immune and immune cells are proposed key players in atherosclerosis development. In the present st...
The effect of hydroxychloroquine on cholesterol metabolism in statin treated patients after myocardial infarction [0.03%]
他汀治疗的心梗患者使用羟氯喹对胆固醇代谢的影响研究
Lotta Ulander,Piia Simonen,Heli Tolppanen et al.
Lotta Ulander et al.
Background and aims: To evaluate the effect of hydroxychloroquine (HCQ) on serum and lipoprotein lipids and serum biomarkers of cholesterol synthesis and absorption in myocardial infarction patients with a high-dose stati...
The German CaRe high registry for familial hypercholesterolemia - Sex differences, treatment strategies, and target value attainment [0.03%]
德国CaRe办公室高胆固醇血症家系注册研究：性别差异、治疗策略及目标实现状况
Winfried März,Nina Schmidt,Ira An Haack et al.
Winfried März et al.
Background and aims: Familial hypercholesterolemia (FH) is among the most common genetic disorders in primary care. However, only 15% or less of patients are diagnosed, and few achieve the goals for low-density lipoprotei...