The pro-atherogenic enzyme PAPP-A is active in eluates from human carotid and femoral atherosclerotic plaques
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Background: Pregnancy-associated plasma protein-A (PAPP-A) regulates bioavailability of insulin-like growth factor 1 (IGF1) in various tissues by proteolytic cleavage of a subset of IGF-binding proteins (IGFBPs). Pre-clinical stu... ...
