Time to pregnancy in women with rheumatoid arthritis who want to conceive treated according to a treat-to-target approach: a comparison of an observational cohort with a historical reference cohort [0.03%]
风湿性关节炎患者的妊娠时机:治疗达标策略的观察队列与历史参考队列间的对比研究
Cornelia H Quaak,Esther Röder,Hetty M Wintjes et al.
Cornelia H Quaak et al.
Background: Time to pregnancy is prolonged in women with rheumatoid arthritis. Rheumatoid arthritis-related factors that influence time to pregnancy include high disease activity, high daily prednisone intake (exceeding 7...
Vincenzo Venerito,Giuseppe Lopalco,Florenzo Iannone et al.
Vincenzo Venerito et al.
Large language models have generated intense interest in clinical artificial intelligence (AI), yet their evolution from passive chatbots into agentic systems capable of autonomous planning, tool use, and multistep execution represents a di...
Towards standardised endpoints: disease activity criteria in adult-onset Still's disease [0.03%]
朝向标准化的终点:成人Still病的疾病活动标准
Stefan Vordenbäumen
Stefan Vordenbäumen
Development and validation of clinical criteria for the definition of disease activity in adult-onset Still's disease: a cohort study [0.03%]
成人斯蒂尔病临床活性定义标准的制定和验证:队列研究
Piero Ruscitti,Tanja Stamm,Valentin Ritschl et al.
Piero Ruscitti et al.
Background: The use of heterogeneous empirical definitions to assess disease activity in adult-onset Still's disease limits evidence on the efficacy of immunosuppressive agents. Thus, we aimed to specifically develop and ...
Certolizumab pegol, abatacept, tocilizumab or active conventional therapy in early rheumatoid arthritis: 48-week patient-reported outcomes from the NORD-STAR trial [0.03%]
早期类风湿性关节炎的 Certolizumab Pegol、Abatacept、Tocilizumab 或积极常规治疗:NORD-STAR试验中为期48周的患者报告结果
Jon Lampa,Dan Nordström,Ronald van Vollenhoven et al.
Jon Lampa et al.
Background: Pain, fatigue, and impaired health-related quality of life are common manifestations of rheumatoid arthritis. The aim of this study was to compare the effects of active conventional treatment with three differ...
Randomized Controlled Trial
The Lancet. Rheumatology. 2026 Apr;8(4):e285-e294. DOI:10.1016/S2665-9913(26)00007-X 2026
Development of patient-initiated follow-up resources for UK rheumatology departments: a co-design study with patient and clinician collaboration [0.03%]
患者和临床医生合作设计英国风湿病学部门的以患者为中心的随访资源配置方案研究
Alice E Jennings,Ailsa Bosworth,Mel Brooke et al.
Alice E Jennings et al.
Background: Patient-initiated follow-up (PIFU) is designed to give patients more control over their follow-up care in rheumatology and relies on patients coming forward to schedule appointments and understand how and when...
LupusGPT: an AI-driven information model for patients with systemic lupus erythematosus [0.03%]
狼疮GPT:一种针对系统性红斑狼疮患者的AI驱动信息模型
Zoe Karakikla-Mitsakou,Alain Cornet,Jeanette Andersen et al.
Zoe Karakikla-Mitsakou et al.
Marie Falahee
Marie Falahee
The Lancet Rheumatology
The Lancet Rheumatology
A treat-to-target strategy versus symptom-driven management of gout in the Netherlands (GO TEST Overture): a multicentre, open-label, pragmatic, superiority, randomised controlled trial [0.03%]
荷兰的痛风治疗目标与症状驱动管理比较研究(GO TEST Overture):多中心、开放标签、实际可行的非劣性随机对照试验
Anusha Moses,Martijn A H Oude Voshaar,Eva H van Geel et al.
Anusha Moses et al.
Background: A treat-to-target approach is recommended for gout management, which involves titrating urate-lowering therapy to reach a serum urate target of less than 0·36 mmol/L, but evidence from pragmatic, head-to-head...