Pregnancy outcomes in patients with systemic vasculitis in the USA from 2007 to 2022: an administrative claims-based study [0.03%]
美国2007年至2022年系统性血管炎患者的妊娠结局:基于行政索赔的研究
Audra Horomanski,Amadeia Rector,Gary M Shaw et al.
Audra Horomanski et al.
Background: Systemic vasculitides are rare, heterogeneous, inflammatory disorders associated with high morbidity and mortality. Recent therapeutic advancements have improved life expectancy and reproductive opportunities ...
Revisiting safety and refining benefit of rituximab-belimumab combination for refractory SLE [0.03%]
利妥昔单抗联合贝利木单抗治疗难治性SLE的安全性再评估及疗效优化
Michael R Ehrenstein,Muhammad Shipa,Kashfia Chowdhury et al.
Michael R Ehrenstein et al.
Anti-BCMA CAR-T for the treatment of IgG4-related disease: clinical assessment and single-cell transcriptomic analysis [0.03%]
抗BCMA的CAR-T治疗IgG4相关性疾病:临床评估和单细胞转录组分析
Shaozhe Cai,Yu Chen,Cong Ye et al.
Shaozhe Cai et al.
Skeletal muscle effects of Janus kinase inhibition in rheumatoid arthritis (RAMUS): a single-arm, experimental medicine study [0.03%]
Janus激酶抑制对类风湿关节炎患者骨骼肌影响的单臂研究(RAMUS研究)
Joshua L Bennett,Kieren G Hollingsworth,Arthur G Pratt et al.
Joshua L Bennett et al.
Background: Rheumatoid arthritis increases the risk of generalised muscle wasting, with chronic inflammation contributing to the loss of muscle mass and strength. Tofacitinib, a Janus kinase (JAK) inhibitor used to treat ...
Jin Kyun Park,Eun Bong Lee
Jin Kyun Park
The relationship between clinical disease activity, synovial inflammatory profile, and treatment response in rheumatoid arthritis [0.03%]
类风湿关节炎临床疾病活动度、滑膜炎症特征与治疗反应的关系
Clément Triaille,Patrick Durez,Francesco Natalucci et al.
Clément Triaille et al.
Synovial tissue is widely considered to be a strong candidate for contributing to the development of individualised therapeutic strategies for the treatment and management of rheumatoid arthritis. Recently, several factors have enabled majo...
Exploiting a unified vascular framework to predict organ-specific complications and accomplish disease modification in systemic sclerosis [0.03%]
利用统一的血管框架预测系统性硬化症的器官特异性并发症并实现疾病修饰
John D Pauling,Yannick Allanore,Maya H Buch et al.
John D Pauling et al.
Immune-mediated vascular endothelial injury is considered one of the earliest pathological features in systemic sclerosis and is thought to occur simultaneously within a broad range of organs, although typically clinically manifesting only ...
Risk factors for interstitial lung disease in early rheumatoid arthritis and external validation of screening strategies: a cross-sectional analysis of the prospective SAIL-RA cohort in the USA [0.03%]
美国SAIL-RA前瞻性队列的横断面分析:类风湿关节炎早期特发性肺间质疾病的危险因素及筛查策略的外部验证研究
Gregory C McDermott,Ritu Gill,Suzanne Byrne et al.
Gregory C McDermott et al.
Background: Evaluation of risk factors and screening strategies for rheumatoid arthritis-associated interstitial lung disease (ILD) in patients with early rheumatoid arthritis has been scarce. We investigated the prevalen...
Synovial immunopathology in psoriatic arthritis: cellular and molecular insights [0.03%]
银屑病关节炎的滑膜免疫病理学:细胞和分子见解
Ryan Malcolm Hum,Maria Christofi,Samantha Louise Smith et al.
Ryan Malcolm Hum et al.
Although psoriatic arthritis and rheumatoid arthritis are both common types of inflammatory arthritis characterised by synovial inflammation, there are distinct molecular and cellular landscapes between these conditions. Recent advances in ...