Naina McCann,Pratyasha Saha,Melissa Chowdhury et al.
Naina McCann et al.
The erosion of seronegative autoimmune diseases through the lens of autoantibodies [0.03%]
自身抗体视角下的自身免疫性疾病阴影范围的缩减
Carlo Selmi,Antonio Tonutti,Suraj Timilsina et al.
Carlo Selmi et al.
Autoantibodies are central to the diagnosis, classification, and stratification of many autoimmune diseases, particularly those characterised by B-cell activation and MHC class II associations. However, a substantial proportion of patients ...
Re-evaluating anti-AT1A1 for predicting fetal atrioventricular block in anti-SSA/Ro positive pregnancies [0.03%]
抗AT1A1抗体用于预测抗SSA/Ro阳性孕妇胎儿房室传导阻滞的临床价值再评价
Philip M Carlucci,Nalani Sachan,Diptendu Chatterjee et al.
Philip M Carlucci et al.
Beyond MRI positivity in axial spondyloarthritis: the ubiquity of bone marrow oedema and risk of overinterpretation [0.03%]
骶髂关节炎的MRI阳性之外:骨髓水肿的普遍性及过度解读的风险
Gaëlle Varkas,Victoria Navarro-Compán
Gaëlle Varkas
When and how chronicity develops in rheumatoid arthritis: towards a temporal and tissue-integrated perspective [0.03%]
论风湿性关节炎的慢性化发展及其时间与组织综合视角
Alper Cevirgel,Annette H M van der Helm-van Mil
Alper Cevirgel
Although the diagnosis of rheumatoid arthritis can usually be made once clinical arthritis appears, this moment does not represent the biological onset of disease. Rheumatoid arthritis develops over a period of years in preclinical phases t...
The end for avacopan [0.03%]
阿瓦西普的终结?
The Lancet Rheumatology
The Lancet Rheumatology
Gwenny M Verstappen,Zana Brkic
Gwenny M Verstappen
Interferon-α as a precision medicine tool in Sjögren's disease: a cohort and experimental medicine study [0.03%]
干扰素α作为类风湿性关节炎的精准医疗工具:队列和实验医学研究
Deborah Forbes,Ivana Jorgacevic,Jessica Tarn et al.
Deborah Forbes et al.
Background: Mechanistic heterogeneity is a major obstacle to the development of effective treatment for Sjögren's disease, and there is a pressing need to stratify Sjögren's disease according to precision medicine princ...
Long-term durability of a time-limited methotrexate intervention in patients with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative arthralgia at increased risk for rheumatoid arthritis (TREAT EARLIER): 5-year data from a double-blind, randomised, placebo-controlled trial [0.03%]
针对类风湿关节炎高危抗瓜氨酸蛋白抗体阳性和阴性关节痛患者的甲氨蝶呤限时干预长期疗效:EARLIER试验5年数据报告一项双盲随机安慰剂对照试验
Elise van Mulligen,Quirine A Dumoulin,Hanna W van Steenbergen et al.
Elise van Mulligen et al.
Background: The TREAT EARLIER trial showed that a time-limited intervention with 12 months of methotrexate in individuals with arthralgia at risk of rheumatoid arthritis improved inflammatory burden but did not prevent rh...