Trends in mortality due to haemophagocytic lymphohistiocytosis across 29 European countries from 2011 to 2021: a retrospective, international, population-based study [0.03%]
2011年至2021年欧洲29个国家噬血细胞性淋巴组织细胞增多症死亡率趋势的回顾性、国际性和基于人群的研究
Leher Gumber,Reza Omidvar,Francesca Gonnelli et al.
Leher Gumber et al.
Background: Previous research has suggested that the incidence of haemophagocytic lymphohistiocytosis is increasing in Europe. We aimed to examine rates of mortality due to haemophagocytic lymphohistiocytosis across 29 Eu...
Cornelia Lachmann,Gunnar Lachmann
Cornelia Lachmann
Time to lift the moratorium on IL-23 inhibitors for axial psoriatic arthritis [0.03%]
解除IL-23抑制剂治疗轴性银屑病关节炎禁令的时候到了
Antonio Tonutti,Kerem Abacar,Tom Macleod et al.
Antonio Tonutti et al.
The disappointment stemming from IL-23 inhibition failure in axial spondyloarthritis has resulted in expert panels extrapolating these results to axial psoriatic arthritis, with recommendations against the use of IL-23 inhibitors in this se...
Farzana Shumy,Kotaro Matsumoto
Farzana Shumy
Intensive biological DMARD-first strategy versus standard step-up care in psoriatic arthritis (STAMP): 1-year results from a multicentre, open-label, randomised controlled trial comparing two treat-to-target strategies [0.03%]
针对银屑病关节炎的强化初始生物改善病情抗风湿药治疗与标准序贯治疗方法的多中心开放标签随机对照试验(STAMP):为期一年的结果比较两种治疗至目标策略的有效性
Gonul Hazal Koc,Marc R Kok,Fazira R Kasiem et al.
Gonul Hazal Koc et al.
Background: Treat-to-target strategies have previously been shown to improve outcomes in psoriatic arthritis. We aimed to evaluate whether a treat-to-target strategy using early intensive treatment with the IL-17A inhibit...
Clinical phenotypes, classification, and long-term outcomes of childhood-onset Sjögren's disease into adulthood: a single-centre cohort study [0.03%]
儿童原发性干燥综合征的临床表型、分类及长期预后:单中心队列研究
Coziana Ciurtin,Junjie Peng,Ruby Taylor-Gotch et al.
Coziana Ciurtin et al.
Background: Childhood-onset Sjögren's disease is a rare and under-investigated rheumatic condition. The natural course of childhood-onset Sjögren's disease in adulthood in not known. This study aimed to evaluate long-te...
Cardiovascular risk factor control in antiphospholipid syndrome, and differences between primary and systemic lupus erythematosus-related antiphospholipid syndrome (SURF-SLE and APS project): a cross-sectional study of 1003 individuals from 11 countries [0.03%]
抗磷脂综合征心血管危险因素的控制及其与原发性抗磷脂综合征和系统性红斑狼疮相关性抗磷脂综合征之间差异的研究(SURF-SLE和APS项目):一项针对来自11个国家/地区的1003名个体的横断面研究
Eleana Bolla,Anne Grete Semb,Michelle Petri et al.
Eleana Bolla et al.
Background: The European Alliance of Associations for Rheumatology recommendations for cardiovascular risk management highlighted the importance of traditional cardiovascular risk factor control in antiphospholipid syndro...
Torsten Diekhoff,Denis Poddubnyy
Torsten Diekhoff
Assessing clinical and cost effectiveness of total versus partial knee replacement (TOPKAT): 10-year follow-up of a multicentre, randomised controlled trial [0.03%]
全膝关节置换术与半膝关节置换术的临床和经济效益评估(TOPKAT):一项多中心随机对照试验的十年随访结果
David J Beard,Loretta J Davies,Jonathan A Cook et al.
David J Beard et al.
Background: The Total or Partial Knee Arthroplasty Trial (TOPKAT) aimed to evaluate the difference between total knee replacement (TKR) and partial (unicompartmental) replacement (PKR) for treatment of late-stage medial c...