The persistence of changes in insulin sensitivity and metabolic gene expression after acute exercise in male and female mice [0.03%]
短暂运动后小鼠胰岛素敏感性及代谢基因表达的持久变化
Jack H Thompson,Alexa M Fooskas,Erica J Locke et al.
Jack H Thompson et al.
Background: Acute exercise has been suggested to increase insulin sensitivity, although the duration of the improvement may last anywhere from 4 to 72 h. In addition, changes in gene expression in response to exercise is ...
Carnosine ameliorates dexamethasone-induced muscle atrophy with associated modulation of ubiquitin ligases and oxidative stress in C57BL/6J female mice [0.03%]
卡那辛改善脱氧皮质醇诱导的小鼠肌肉萎缩及相关的泛素连接酶和氧化应激调节作用（C57BL/6J雌性小鼠模型）
Md Mizanur Rahman,Anayt Ulla,Honomi Ogura et al.
Md Mizanur Rahman et al.
Muscle atrophy, characterized by a decline in muscle mass and function, has limited treatment options, highlighting the need for further research. In this study, we investigated the effect of carnosine, a dipeptide with well-established ant...
The senescent synapse: A look at autophagy, calcium handling, and mitochondrial bioenergetics at the synapse in ageing and Parkinson's disease [0.03%]
衰老的突触：老化和帕金森病中突触自噬、钙离子稳态及线粒体生物能学研究一瞥
Shahzabe Mukhtar,Shikha Kataria,Gloria Cimaglia et al.
Shahzabe Mukhtar et al.
The synapse is a vitally important physiological structure fundamental to electrochemical communication between neurones, and is required for basic and important functions we perform daily. Underpinning the normal physiological function of ...
Mechanisms involved in aminoacidurias: impacts of genetic and environmental factors [0.03%]
氨基酸尿的发病机制：遗传和环境因素的影响
Joseph Abayomi Ajayi,Evelyn Nnashiru Ananias,Muneerah Issa-Lawal et al.
Joseph Abayomi Ajayi et al.
Background: Amino acids play vital roles in protein synthesis, energy metabolism, and cellular function. Aminoacidurias are metabolic disorders characterized by excessive urinary excretion of amino acids resulting from de...
The beneficial effect of propolis during an eight-weeks of resistance training on TNF-α and IL-6 genes expression in the kidney tissue of female Wistar rats undergoing testosterone enanthate consumption [0.03%]
八周阻抗训练联合使用巴西蜂胶和庚酸睾酮对雌性威斯特大鼠肾脏组织中TNF-α和IL-6基因表达的影响研究
Khadijeh Molaei,Sanaz Mirzayan Shanjani,Ali Gorzi et al.
Khadijeh Molaei et al.
This study investigated the potential benefits of propolis in mitigating the adverse effects of testosterone enanthate on the gene expression levels of pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-...
Vascular adaptation in elite female and male rowers across a competitive season [0.03%]
精英男女赛艇运动员在一个竞赛赛季中的血管适应性变化
Sarah R Henley-Martin,Carly J Brade,Hugh Riddell et al.
Sarah R Henley-Martin et al.
The 'athlete's artery' phenotype describes exercise-induced vascular adaptation whereby athletes have enlarged conduit arteries resulting from chronic endurance exercise. However, studies remain limited to males, with few evaluating changes...
Using digital escape rooms to enhance data analysis skills and student experience in a higher education human physiology module [0.03%]
使用数字密室逃脱游戏提高高等教育人机生理学模块中的数据分析技能和学生体验
Nicola Morgan,Marriam Yaqoob,Matthew Allan Jones
Nicola Morgan
Active and gamified teaching methods have garnered significant interest, with an increased demand for higher education institutions to enhance student engagement. One popular example of active learning is the escape room. Escape rooms are p...
Sex and dose differences in morphine administration on renal function, inflammatory and apoptotic markers in male and female Wistar rats [0.03%]
吗啡对雄性和雌性Wistar大鼠肾功能、炎症和凋亡标志物的影响及剂量反应关系研究
Olaoluwa Sesan Olukiran,Oluwadare Joshua Ogundipe,Stephen Taiye Adelodun et al.
Olaoluwa Sesan Olukiran et al.
This study examined the impact of morphine on renal function, antioxidant enzymes, and inflammatory and apoptotic markers in male and female Wistar rats, considering both sex- and dose-dependent effects. 40 Wistar rats (20 male, 20 female),...
High-intensity training and irisin response: A possible molecular cross-talk for irisin response [0.03%]
高强度训练与irisin反应：irisin反应的可能分子串话
Ping Li,Ligang Tong,Xuecui Bi
Ping Li
Physical exercise is widely recognized for its positive effect on health through alterations in genetic, molecular, or tissue-level pleiotropic effects. The extent of these advantages hinges on the intensity that elicits optimal threshold a...
Serena Y Kuang,Xiaoqi Yang,Xiaonan Li
Serena Y Kuang
Tonicity is the most confusing concept in teaching about osmosis in physiology, biology, and many clinical disciplines. A total of seven causes (four superficial and three deep) have led to this confusion but have never been thoroughly clar...