Ting Wang,Hang Xing,Lei Huang et al.
Ting Wang et al.
Background: Brain metastases (BM) significantly affect both prognosis and quality of life in patients with metastatic non-small cell lung cancer (NSCLC), highlighting the need for innovative therapeutic strategies. In thi...
Anna G Hauswirth,Michael W Parsons,Jorg Dietrich
Anna G Hauswirth
Immunotherapies engage the individual's immune system to fight both hematologic and solid malignancies and have led to durable clinical responses for many patients. A subset of immunotherapies, including T cell engagers (TCEs) and chimeric ...
The neurobiology of survivorship: Cognitive consequences of modern oncology [0.03%]
肿瘤学的神经生物学：现代肿瘤学的认知后果
Maciej M Mrugala,Michelle Monje
Maciej M Mrugala
Executive function after childhood cancer: Insights from network neuroscience [0.03%]
网络神经科学视角下的儿童癌症幸存者的执行功能损伤机制研究
Katie Wade Alonso,Donald J Mabbott
Katie Wade Alonso
In this review, we examine the empirical literature on the cognitive late effects of childhood acute lymphoblastic leukemia (ALL) and brain tumors, with a focus on executive function and its neural underpinnings. Executive function is a cri...
Chemotherapy neurotoxicity and aging: Uncovering shared central nervous system pathologies and potential interventions [0.03%]
化疗神经毒性与衰老：揭示共有的中枢神经系统病理及潜在干预措施
Maria Sacconi Nunez,Erin M Gibson
Maria Sacconi Nunez
Advances in cancer therapies have significantly improved survival rates, but many survivors face persistent cognitive impairments collectively termed chemotherapy-related cognitive impairment (CRCI). Symptoms such as memory deficits, reduce...
Bryan J Neth,Sanne B Schagen,Jeffrey S Wefel
Bryan J Neth
There is a growing number of cancer survivors given improvement in early cancer diagnosis, therapeutics, and supportive care strategies. Cognitive impairment is among the most common and clinically significant symptoms managed by cancer sur...
A phase 1 trial of iron metabolism-targeting oral gallium maltolate in recurrent and refractory glioblastoma [0.03%]
口服半乳矿酸治疗复发和难治性胶质母细胞瘤的铁代谢靶向一期临床试验
Jennifer M Connelly,Casey J Zoss,Aniko Szabo et al.
Jennifer M Connelly et al.
Background: Gallium maltolate is an oral compound that disrupts iron-dependent glioblastoma (GBM) growth and prolongs survival in animal models. This Phase 1 trial of oral gallium maltolate in patients with recurrent GBM ...
Phase 2 study of regorafenib in patients with progressive glioblastoma after failure of bevacizumab [0.03%]
瑞戈非尼治疗贝伐珠单抗失败后病情进展的胶质母细胞瘤患者的II期研究
Alyssa Lucas,David Peereboom,Yasmeen Rauf et al.
Alyssa Lucas et al.
Background: Treatment options in progressive glioblastoma (GBM) are limited, especially in patients who have experienced disease progression while receiving bevacizumab therapy. This phase 2 study was conducted to evaluat...
Impact of infratentorial location on survival after surgical resection of brain metastases: a multicenter retrospective study [0.03%]
脑转移瘤术后颅内生存期对预后的影响：多中心回顾性研究
Artem Rafaelian,Matthias Schneider,Daniel Dubinski et al.
Artem Rafaelian et al.
Purpose: Infratentorial brain metastases (BMs) pose distinct clinical challenges, but their prognostic relevance remains unclear. This study evaluated the impact of infratentorial location on survival after surgical resec...
Konstantin Weise,Nikola Mikic,Fang Cao et al.
Konstantin Weise et al.
Background: Tumor Treating Fields (TTFields) provide a noninvasive treatment option for newly diagnosed glioblastoma. While electrode placement is considered important for treatment efficacy, current clinical planning rel...