Jie Shen,Mengyu Zhang,Meiyu Peng
Jie Shen
Systemic lupus erythematosus (SLE) is a global chronic autoimmune disease that invades most organs of the body, with kidney injury being the most prominent feature. Exosomes are extracellular vesicles that carry a variety of proteins, lipid...
Plasminogen activator inhibitor-1 mediate downregulation of adiponectin in type 2 diabetes patients with metabolic syndrome [0.03%]
PAI-1介导的代谢综合征2型糖尿病患者脂联素下调的作用
Shaik Sarfaraz Nawaz,Khalid Siddiqui
Shaik Sarfaraz Nawaz
Introduction: Metabolic syndrome (MetS) is a multifactorial disease characterized by metabolic abnormalities. Plasminogen activator inhibitor-1(PAI-1) is a key factor of the fibrinolysis its expression is elevated in insu...
An exploratory study of circulating cytokines and chemokines in patients with muscle disorders proposes CD40L and CCL5 represent general disease markers while CXCL10 differentiates between patients with an autoimmune myositis [0.03%]
循环细胞因子和化学趋化因子的探索性研究提出了CD40L和CCL5代表一般疾病标志物而CXCL10可区分自身免疫性肌炎患者
Boel De Paepe,Ken R Bracke,Jan L De Bleecker
Boel De Paepe
Discriminating an autoimmune myositis from other disorders and subtyping of patient groups within this heterogeneous group of conditions remain diagnostic challenges. In our study we explored the potential of cytokine and chemokine typing i...
TNFAIP8 modulates the survival and immune activity of Th17 cells via p53/ p21/ MDM2 pathway after acute insult [0.03%]
TNFAIP8通过p53/p21/MDM2途径调节急性损伤后Th17细胞的存活和免疫活性
Xiaobin Cheng,Xiaocheng Shen,Min Wang et al.
Xiaobin Cheng et al.
Th17 cells induced immunosuppression plays a vital role in sepsis. As a member of the tumor necrosis factor α induced protein 8 (TNFAIP8) family, TNFAIP8 is associated with different physiopathological conditions with immunological respons...
Exclusive inhibition of IL-6 trans-signaling by soluble gp130FlyRFc [0.03%]
可溶性gp130FlyRFc特异性抑制白细胞介素-6旁路信号转导
Anna F Berg,Julia Ettich,Hendrik T Weitz et al.
Anna F Berg et al.
gp130 is the signal-transducing receptor for the Interleukin (IL)-6 type cytokines IL-6 and IL-11. To induce signaling, IL-6 forms a complex with IL-6 receptor (IL-6R) and IL-11 with IL-11 receptor (IL-11R). Membrane-bound IL-6R and IL-11R ...
Interferon-gamma impairs phagocytosis of Escherichia coli by primary murine peritoneal macrophages stimulated with LPS and differentially modulates proinflammatory cytokine release [0.03%]
干扰素-γ损害LPS刺激的小鼠腹膜巨噬细胞对大肠杆菌的吞噬，并差异调节促炎细胞因子的释放
Sandra Schütze,Annika Kaufmann,Stephanie Bunkowski et al.
Sandra Schütze et al.
Introduction: Interferon-γ levels are increased upon viral infections and during inflamm-aging. Resistance to infections due to Escherichia coli (E. coli), a major cause of bacteriaemia and sepsis, is impaired in aged in...
Interferon stimulated binding of ISRE is cell type specific and is predicted by homeostatic chromatin state [0.03%]
干扰素刺激的ISRE结合具有细胞类型特异性，并且可以由稳态染色质状态预测
Sivan Leviyang
Sivan Leviyang
The type I interferon (IFN) signaling pathway involves binding of the transcription factor ISGF3 to IFN-stimulated response elements, ISREs. Gene expression under IFN stimulation is known to vary across cell types, but variation in ISGF3 bi...
Disruption of type I interferon signaling causes sexually dimorphic dysregulation of anti-viral cytokines [0.03%]
I型干扰素信号紊乱导致抗病毒细胞因子失调
Maedeh Darzianiazizi,Katrina E Allison,Raveendra R Kulkarni et al.
Maedeh Darzianiazizi et al.
Type I interferons (IFNs) play a crucial role in the establishment of an antiviral state via signaling through their cognate type I IFN receptor (IFNAR). In this study, a replication-competent but highly attenuated strain of VSV (rVSVΔm51)...
Resistin in pregnancy: Analysis of determinants in pairs of umbilical cord blood and maternal serum [0.03%]
抵抗素在妊娠中的作用：脐带血和母体血清中决定因素的分析
Anne Floeck,Nina Ferrari,Christine Joisten et al.
Anne Floeck et al.
Objective: Despite intensive research on the cytokine resistin only few studies investigated mother-newborn-pairs during healthy pregnancy and reported about interactions with clinical obstetric variables or other cytokin...
Erratum to "Macrophage migration inhibitory factor (MIF) and pregnancy may impact the balance of intestinal cytokines and the development of intestinal pathology caused by Toxoplasma gondii infection" [Cytokine: X 2 (2020) 100034] [0.03%]
关于“巨噬细胞迁移抑制因子(MIF)和妊娠可通过影响肠道细胞因子平衡来影响由弓形虫感染引起的肠病的发展”一文的勘误通知
Camila Ferreira Marcon,Paula Tatiana Mutão Ferreira,Priscila Silva Franco et al.
Camila Ferreira Marcon et al.
[This corrects the article DOI: 10.1016/j.cytox.2020.100034.]. © 2020 The Author(s).
Published Erratum
Cytokine: X. 2020 Sep 21;2(3):100040. DOI:10.1016/j.cytox.2020.100040 2020