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Disruption of type I interferon signaling causes sexually dimorphic dysregulation of anti-viral cytokines

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Type I interferons (IFNs) play a crucial role in the establishment of an antiviral state via signaling through their cognate type I IFN receptor (IFNAR). In this study, a replication-competent but highly attenuated strain of VSV (rVSVΔm51) carrying a deletion... ...