Evaluating CTLA-4 Antibody-Antigen Binding as a Model for Targeted Immunosuppressant Delivery in Hashimoto's Thyroiditis [0.03%]
评估CTLA-4抗体-抗原结合作为Hashimoto甲状腺炎靶向免疫抑制剂递送模型的方法
Vinayan Tiruvellore,Mike Koegle
Vinayan Tiruvellore
Autoimmune disorders such as Hashimoto's thyroiditis lack curative treatments, only therapeutic agents that treat symptoms very broadly and dampen the entire immune system, including healthy cells. Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) ...
Genome Sequences of Bacteriophages Natasha and RustyBoy, Isolated on Arthrobacter globiformis , and Fazel, Isolated on Gordonia rubripertincta in Southwestern New Mexico [0.03%]
新墨西哥州南部分离的棒状噬菌体Natasha和RustyBoy以及红色分枝杆菌Fazel的基因组序列
Rebecca Merchant,Violet Kirk,Isabella McClish et al.
Rebecca Merchant et al.
We report the discovery and genome sequence of three phages with siphovirus morphology isolated from soil collected in Socorro, New Mexico. Phages Natasha and RustyBoy, which were isolated using Arthrobacter globiformis B-2979, are both ass...
S. mutans induces developmental and morphological defects in C. elegans despite prior L. casei exposure [0.03%]
乳酸菌暴露仍会导致链球菌诱导的小鼠秀丽隐杆线虫发育和形态缺陷
Ana M Cedeno Escobar,Katherine M Walstrom
Ana M Cedeno Escobar
Imbalances between pathogenic and commensal bacteria cause microbial dysbiosis that disrupts host development. Streptococcus mutans ' virulence factors promote human oral cell colonization, leading to dysbiosis if unchecked. When grown with...
Long term exposure to dietary cannabinoids inhibits rapid functional tolerance to ethanol in Drosophila melanogaster adults [0.03%]
大麻素抑制果蝇成虫快速饮酒耐受性
Alyssa Vidal,Sandra Illescas,Vivian Le et al.
Alyssa Vidal et al.
In rodents, exposure to cannabidiol (CBD) was shown to alter responses to alcohol, primarily via CB1/CB2 signaling. However, CBD also targets non-canonical receptors whose potential roles in modulating CBD-alcohol interactions remain unknow...
Seizure Susceptibility in Drosophila melanogaster is Reduced with CBD and Z. jujube treatment [0.03%]
大麻二酚和酸枣仁对果蝇癫痫的防治作用
Zakary Kubitz,Jonathan Goedken,Brylee O&#x;Neill et al.
Zakary Kubitz et al.
Seizures have a bidirectional relationship to sleep deprivation; sleep loss increases seizure susceptibility and duration, while seizures disrupt sleep (Mituzaite et al., 2021; Konduru et al., 2021). This study tested whether two treatments...
Arion vulgaris pedal epithelium displays fluorescence patterns consistent with uptake of Nicotiana tabacum extracellular dye-labeled vesicles ex vivo [0.03%]
乳状隐花鱼足部上皮的荧光图案与从活烟草植株中吸收含标记染料的胞外囊泡一致
Michaela Liegertová,Monika Iljučoková,Jiří Smejkal et al.
Michaela Liegertová et al.
Cross-kingdom trafficking of extracellular vesicles (EVs) is documented between plants and fungal pathogens, yet evidence for plant-herbivore exchange remains scarce. Here we show that EVs isolated from Nicotiana tabacum suspension cultures...
Complete genome sequence of bacteriophage Byron23 targeting Microbacterium foliorum [0.03%]
针对Microbacterium foliorum的菌噬菌体Byron23完整基因组序列
Francisco J Moro,M Victoria Vallejos,Gina Cervesato et al.
Francisco J Moro et al.
In this paper, we report the discovery and characterization of Byron23, a bacteriophage isolated from a soil sample collected approximately 30 cm beneath the surface of a stream bank in Rosario, Santa Fe, Argentina. Byron23 infected the hos...
Erratum: Corrigendum: Schwann cell deletion of Tumor Susceptibility Gene 101 ( Tsg101 ) in mice results in severe peripheral neuropathy [0.03%]
Correction: 神经鞘瘤细胞中TSG101基因缺失致小鼠外周神经病严重化
[This corrects the article DOI: 10.17912/micropub.biology.001406.]. Copyright: © 2025 by the authors.
Erin Frank,Iris Pardue,Ifti Rahman et al.
Erin Frank et al.
Some organisms can regrow severed body parts. In vertebrates, the anabolic pentose phosphate pathway (PPP) aids regeneration, but we do not know if invertebrates require the PPP for regeneration. To test this, we attempted to inhibit the PP...
Jazmine Aftabi,Shivani Gangireddy,Uttej Kollu et al.
Jazmine Aftabi et al.
Bacteriophage Ichiang is a siphovirus capable of infecting Arthrobacter globiformis B2979. The genome has a length of 41,984 base pairs with 64.8 % GC content and contains 64 predicted protein-coding genes and 1 tRNA gene. Based on gene con...