Genome Sequence and Characteristics of Cluster AS3 Arthrobacter globiformis Phages Atlantica, Babushka, DanHam62, and Glotell [0.03%]
集群AS3微小噬菌体Atlantica、Babushka、DanHam62和Glotell的基因组序列及其特征
Sarah Bakayoko,Justin Chen,Yu-Chuan Chen et al.
Sarah Bakayoko et al.
We report the discovery and characterization of four phages infecting Arthrobacter globiformis B-2979 that are all assigned to actinobacteriophage subcluster AS3 based on gene content similarity. These phages have genomes of approximately 3...
Exploring phosphoregulation of MYO3A using quantitative fluorescence image analysis in COS7 cells [0.03%]
定量荧光图像分析在COS7细胞中探索MYO3A的磷酸化修饰
Vu M N Phan,Omar Alberto Quintero-Carmona
Vu M N Phan
Myosin IIIA is an unconventional myosin that contains a kinase domain, and is involved in the formation of hair-cell stereocilia. To investigate its regulatory roles, we mimicked phosphorylation in mchr-MYO3AΔK constructs and assayed their...
Paralog-specific miRNA regulation uncouples ASER gene repression from the canonical die-1 / cog-1 switch [0.03%]
特异作用于旁系同源物的miRNA调节解耦ASER基因抑制与经典的die-1 / cog-1开关
Lara C Khalaf,Dylan L Castro,Sayeda R Qubadi et al.
Lara C Khalaf et al.
The Pristionchus pacificus ASER-specific Ppa-gcy-22 .3 and Ppa-gcy-22 .5 paralogs differ in their regulatory dependencies despite sharing an upstream terminal selector machinery. P. pacificus gcy-22.3 expression is sensitive to Ppa-die-1 an...
Short-term L1 arrest duration does not significantly alter organismal phenotypes in synchronized Caenorhabditis elegans populations [0.03%]
短暂停育时间不会显著改变同步化秀丽隐杆线虫种群的生物表型
Sourabh Behra,Sambhav Dadsena,Kamesh R Babu
Sourabh Behra
Synchronized L1 larvae are commonly maintained under starvation for varying durations prior to experimental use in Caenorhabditis elegans research. However, the effects of short-term L1 arrest duration on downstream phenotypes remain unclea...
Quantification of cki-1 promoter activity during PHso1-to-PHD remodeling in Caenorhabditis elegans [0.03%]
定量分析Caenorhabditis elegans中cki-1启动子活性在PHso1至PHD重塑过程中的变化
Nathazsha Gande,Nicholas Palmisano,Aram Stump
Nathazsha Gande
Cyclin-dependent kinase inhibitor ( cki-1 ) is associated with cell cycle arrest and cellular quiescence. In Caenorhabditis elegans , glia-to-neuron transdifferentiation of the phasmid socket 1 (PHso1) glia into the phasmid D (PHD) neuron h...
Triglyceride Storage is Upregulated in Different Mouse Non-Melanoma Skin Cancer Cell Lines [0.03%]
小鼠不同非黑色素皮肤癌细胞系中的甘油三酯蓄积上调现象
Shannon Nowotarski,Ryan Cunnane,Marissa Catteau et al.
Shannon Nowotarski et al.
Links between tumorigenesis and lipid metabolism have been observed in various cancers, but whether lipid metabolism is altered in skin cancers is not well understood. Here we show that two different mouse skin cancer cell lines accumulate ...
In silico protein structure analysis of nine deleterious NIT1 missense mutations identified in human cancers [0.03%]
人类癌症中鉴定到的九种有害NIT1错义突变的蛋白质结构的计算机分析
Anup Parajuli,Hung Phan,Susan Walsh
Anup Parajuli
NIT1 is a tumor suppressor which functions as a metabolite repair enzyme to process deaminated glutathione (dGSH). Missense variants in NIT1 were analyzed from the COSMIC database to assess their structural and functional consequences. Of 5...
Interspecies distribution and processing stability of ergothioneine and histidine in commercially available mushrooms [0.03%]
商业化蘑菇子实体中麦角硫宁和组氨酸的种间分布及加工稳定性研究
Caden Guthrie,Semir Hasic,Harley Gordon
Caden Guthrie
Ergothioneine is a widespread thiol metabolite present in fungal and bacterial species. Ergothioneine has been demonstrated to increase the lifespan of the model laboratory species C. elegans and M. musculus through increased protein crossl...
Distinct anthelmintic classes do not affect gut bacteria, and bacteria do not alter nematocidal efficacy in Caenorhabditis elegans [0.03%]
不同种类的驱虫药不会影响肠道细菌，细菌也不会改变秀丽隐杆线虫的驱虫效力
Laura Romanelli-Cedrez,Gustavo Salinas
Laura Romanelli-Cedrez
Soil-transmitted helminth infections are widespread and can impair children's nutrition and development. Anthelmintics may interact with the intestinal microbiota; however, they should not disrupt microbes, and microbial metabolism should n...
Will Scott,Nimo Abdullah,Ragnheiður Guðjónsdóttir et al.
Will Scott et al.
Expansion microscopy is a powerful technique for achieving nanoscale resolution, but labelling and detection using fluorescent proteins (FPs) have been hampered by signal degradation during expansion. Current approaches therefore rely heavi...