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Joubert syndrome gene fam149b1 homolog, xbx-4 , is required for multiple sensory behaviors

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Many cells require cilia to receive environmental signals. Mutations in the ciliary gene fam149b1 result in the ciliopathy Joubert syndrome. The C. elegans homolog of fam149b1 , xbx-4 , is required for normal cilium structure. We found that loss of XBX-4 hinde... ...